Myeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertension
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:p>Although essential hypertension affects a large proportion of the human population and is one of the key drivers of cardiovascular mortality worldwide, we still do not have a complete understanding of its pathophysiology. More than 50 years ago, the immune system has been identified as an important part of the pathogenesis of arterial hypertension. An exceeding variety of recent publications deals with the interplay between the numerous different components of the immune system and mechanisms of arterial hypertension and has substantially contributed to our understanding of the role of immunity and inflammation in the pathogenesis of the disease. In this review, we focus on myeloid cells and anatomical barriers as particular aspects of innate immunity in arterial hypertension. Since it represents a first line of defense protecting against pathogens and maintaining tissue homeostasis, innate immunity provides many mechanistic hinge points in the area of hypertension.</jats:p>
- Autoren
- Johannes Wild
- Philip Wenzel
- DOI
- 10.1007/s00109-020-02019-1
- eISSN
- 1432-1440
- ISSN
- 0946-2716
- Ausgabe der Veröffentlichung
- 3
- Zeitschrift
- Journal of Molecular Medicine
- Sprache
- en
- Online publication date
- 2021
- Paginierung
- 315 - 326
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1007/s00109-020-02019-1
- Datum der Datenerfassung
- 2023
- Titel
- Myeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertension
- Ausgabe der Zeitschrift
- 99
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Johannes Wild
- Philip Wenzel
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- JGU-Publikationen
- Resource version
- Published version
- DOI
- 10.1007/s00109-020-02019-1
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 1432-1440
- Zeitschrift
- Journal of molecular medicine
- Schlüsselwörter
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 315 - 326
- Datum der Veröffentlichung
- 2021
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/5879
- Herausgeber
- Springer
- Herausgeber URL
- https://doi.org/10.1007/s00109-020-02019-1
- Datum der Datenerfassung
- 2021
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2021
- Zugang
- Public
- Titel
- Myeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertension
- Ausgabe der Zeitschrift
- 99
Files
wild_johannes-myeloid_cells-20210430210756292.pdf
Data source: OPENSCIENCE.UB