Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort
- Publication type:
- Journal article
- Metadata:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:p>To investigate the prevalence and new onset of depression and anxiety among subjects with age-related macular degeneration (AMD) and its association with AMD in a large European cohort with relatively good visual acuity. 11,834 participants enrolled in the German population-based Gutenberg Health Study were studied. AMD was diagnosed by grading of fundus photographs. Depression and anxiety were assessed with the Patient Health Questionnaire and the Generalized Anxiety Disorder-2 Scale, respectively. Logistic regression analyses were performed and adjusted for several parameters. 1,089 (9.2%) participants were diagnosed having AMD. Prevalence of depression in AMD and non-AMD participants was 7.2% and 8.0%, respectively and prevalence of anxiety was 4.2% and 7.0%, respectively. New onset of depression and anxiety at 5-year follow-up in AMD subjects was 2.6% and 3.6%, respectively. AMD was not associated with depression (OR 0.93; CI 95% 0.70–1.20; p = 0.62). AMD was associated with less anxiety (OR 0.67; CI 95% 0.47–0.93; p = 0.02). This is the first study analyzing both prevalence and new onset of depression and anxiety in AMD subjects. AMD- and non-AMD participants had a similar prevalence and new onset of depression in our population-based sample. Participants without AMD had a higher prevalence of anxiety. AMD was not associated with depression.</jats:p>
- Autoren
- Jasmin Rezapour
- Alexander K Schuster
- Stefan Nickels
- Christina A Korb
- Hisham Elbaz
- Tunde Peto
- Matthias Michal
- Thomas Münzel
- Philipp S Wild
- Jochem König
- Karl Lackner
- Andreas Schulz
- Norbert Pfeiffer
- Manfred E Beutel
- DOI
- 10.1038/s41598-020-61706-8
- eISSN
- 2045-2322
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- Scientific Reports
- Sprache
- en
- Artikelnummer
- 4816
- Online publication date
- 2020
- Status
- Published online
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1038/s41598-020-61706-8
- Datum der Datenerfassung
- 2022
- Titel
- Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort
- Ausgabe der Zeitschrift
- 10
Data source: Crossref
- Other metadata sources:
-
- Author's licence
- CC-BY
- Autoren
- Jasmin Rezapour
- Alexander K Schuster
- Stefan Nickels
- Christina A Korb
- Hisham Elbaz
- Tunde Peto
- Matthias Michal
- Thomas Münzel
- Philipp S Wild
- Jochem König
- Karl Lackner
- Andreas Schulz
- Norbert Pfeiffer
- Manfred E Beutel
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- JGU-Publikationen
- Resource version
- Published version
- DOI
- 10.1038/s41598-020-61706-8
- Funding acknowledgements
- DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 2045-2322
- Zeitschrift
- Scientific Reports
- Schlüsselwörter
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- Art. 4816
- Datum der Veröffentlichung
- 2020
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/5221
- Herausgeber
- Macmillan Publishers Limited, part of Springer Nature
- Herausgeber URL
- https://doi.org/10.1038/s41598-020-61706-8
- Datum der Datenerfassung
- 2020
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2020
- Zugang
- Public
- Titel
- Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort
- Ausgabe der Zeitschrift
- 10
Files
rezapour_jasmin-prevalence_and-20201016123926059.pdf
Data source: OPENSCIENCE.UB