Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials
- Publication type:
- Journal article
- Metadata:
-
- Autoren
- Daniel Pfirrmann
- Nils Haller
- Yvonne Huber
- Patrick Jung
- Klaus Lieb
- Ines Gockel
- Krystyna Poplawska
- Joern Markus Schattenberg
- Perikles Simon
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000433883200034&DestLinkType=FullRecord&DestApp=WOS
- DOI
- 10.2196/resprot.8607
- Externe Identifier
- Clarivate Analytics Document Solution ID: GH7ZL
- PubMed Identifier: 29789277
- ISSN
- 1929-0748
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- JMIR RESEARCH PROTOCOLS
- Schlüsselwörter
- esophageal cancer
- cystic fibrosis
- depression
- nonalcoholic fatty liver disease
- exercise
- eHealth
- Artikelnummer
- ARTN e106
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Titel
- Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials
- Sub types
- Article
- Ausgabe der Zeitschrift
- 7
Data source: Web of Science (Lite)
- Other metadata sources:
-
- Autoren
- Daniel Pfirrmann
- Nils Haller
- Yvonne Huber
- Patrick Jung
- Klaus Lieb
- Ines Gockel
- Krystyna Poplawska
- Jörn Markus Schattenberg
- Perikles Simon
- DOI
- 10.2196/resprot.8607
- eISSN
- 1929-0748
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- JMIR Research Protocols
- Sprache
- en
- Online publication date
- 2018
- Paginierung
- e106 - e106
- Status
- Published online
- Herausgeber
- JMIR Publications Inc.
- Herausgeber URL
- http://dx.doi.org/10.2196/resprot.8607
- Datum der Datenerfassung
- 2018
- Titel
- Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials
- Ausgabe der Zeitschrift
- 7
Data source: Crossref
- Abstract
- <h4>Background</h4>In the primary and secondary prevention of civilization diseases, regular physical activity is recommended in international guidelines to improve disease-related symptoms, delay the progression of the disease, or to enhance postoperative outcomes. In the preoperative context, there has been a paradigm shift in favor of using preconditioning concepts before surgery. Web-based interventions seem an innovative and effective tool for delivering general information, individualized exercise recommendations, and peer support.<h4>Objective</h4>Our first objective was to assess feasibility of our Web-based interventional concept and analyze similarities and differences in a sustained exercise implementation in different diseases. The second objective was to investigate the overall participants' satisfaction with our Web-based concept.<h4>Methods</h4>A total of 4 clinical trials are still being carried out, including patients with esophageal carcinoma scheduled for oncologic esophagectomy (internet-based perioperative exercise program, iPEP, study), nonalcoholic fatty liver disease (hepatic inflammation and physical performance in patients with nonalcoholic steatohepatitis, HELP, study), depression (exercise for depression, EXDEP, study), and cystic fibrosis (cystic fibrosis online mentoring for microbiome, exercise, and diet, COMMED, study). During the intervention period, the study population had access to the website with disease-specific content and a disease-specific discussion forum. All participants received weekly, individual tailored exercise recommendations from the sports therapist. The main outcome was the using behavior, which was obtained by investigating the log-in rate and duration.<h4>Results</h4>A total of 20 participants (5 from each trial) were analyzed. During the intervention period, a regular contact and a consequent implementation of exercise prescription were easily achieved in all substudies. Across the 4 substudies, there was a significant decrease in log-in rates (P<.001) and log-in durations (P<.001) over time. A detailed view of the different studies shows a significant decrease in log-in rates and log-in durations in the HELP study (P=.004; P=.002) and iPEP study (P=.02; P=.001), whereas the EXDEP study (P=.58; P=.38) and COMMED study (P=.87; P=.56) showed no significant change over the 8-week intervention period. There was no significant change in physical activity within all studies (P=.31). Only in the HELP study, the physical activity level increased steadily over the period analyzed (P=.045). Overall, 17 participants (85%, 17/20) felt secure and were not scared of injury, with no major differences in the subtrials.<h4>Conclusions</h4>The universal use of the Web-based intervention appears to be applicable across the heterogonous collectives of our study patients with regard to age and disease. Although the development of physical activity shows only moderate improvements, flexible communication and tailored support could be easily integrated into patients' daily routine.<h4>Trial registration</h4>iPEP study: ClinicalTrials.gov NCT02478996; https://clinicaltrials.gov/ct2/show/NCT02478996 (Archived by WebCite at http://www.webcitation.org/6zL1UmHaW); HELP study: ClinicalTrials.gov NCT02526732; http://www.webcitation.org/6zJjX7d6K (Archived by WebCite at http://www.webcitation.org/6Nch4ldcL); EXDEP study: ClinicalTrials.gov NCT02874833; https://clinicaltrials.gov/ct2/show/NCT02874833 (Archived by WebCite at http://www.webcitation.org/6zJjj7FuA).
- Addresses
- Department of Sports Medicine, Disease Prevention and Rehabilitation, Institute of Sports Science, Johannes Gutenberg University, Mainz, Germany.
- Autoren
- Daniel Pfirrmann
- Nils Haller
- Yvonne Huber
- Patrick Jung
- Klaus Lieb
- Ines Gockel
- Krystyna Poplawska
- Jörn Markus Schattenberg
- Perikles Simon
- DOI
- 10.2196/resprot.8607
- eISSN
- 1929-0748
- Externe Identifier
- PubMed Identifier: 29789277
- PubMed Central ID: PMC5989063
- Open access
- true
- ISSN
- 1929-0748
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- JMIR research protocols
- Sprache
- eng
- Medium
- Electronic
- Online publication date
- 2018
- Open access status
- Open Access
- Paginierung
- e106
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Publisher licence
- CC BY
- Datum der Datenerfassung
- 2018
- Titel
- Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials.
- Sub types
- research-article
- Journal Article
- Ausgabe der Zeitschrift
- 7
Data source: Europe PubMed Central
- Abstract
- BACKGROUND: In the primary and secondary prevention of civilization diseases, regular physical activity is recommended in international guidelines to improve disease-related symptoms, delay the progression of the disease, or to enhance postoperative outcomes. In the preoperative context, there has been a paradigm shift in favor of using preconditioning concepts before surgery. Web-based interventions seem an innovative and effective tool for delivering general information, individualized exercise recommendations, and peer support. OBJECTIVE: Our first objective was to assess feasibility of our Web-based interventional concept and analyze similarities and differences in a sustained exercise implementation in different diseases. The second objective was to investigate the overall participants' satisfaction with our Web-based concept. METHODS: A total of 4 clinical trials are still being carried out, including patients with esophageal carcinoma scheduled for oncologic esophagectomy (internet-based perioperative exercise program, iPEP, study), nonalcoholic fatty liver disease (hepatic inflammation and physical performance in patients with nonalcoholic steatohepatitis, HELP, study), depression (exercise for depression, EXDEP, study), and cystic fibrosis (cystic fibrosis online mentoring for microbiome, exercise, and diet, COMMED, study). During the intervention period, the study population had access to the website with disease-specific content and a disease-specific discussion forum. All participants received weekly, individual tailored exercise recommendations from the sports therapist. The main outcome was the using behavior, which was obtained by investigating the log-in rate and duration. RESULTS: A total of 20 participants (5 from each trial) were analyzed. During the intervention period, a regular contact and a consequent implementation of exercise prescription were easily achieved in all substudies. Across the 4 substudies, there was a significant decrease in log-in rates (P<.001) and log-in durations (P<.001) over time. A detailed view of the different studies shows a significant decrease in log-in rates and log-in durations in the HELP study (P=.004; P=.002) and iPEP study (P=.02; P=.001), whereas the EXDEP study (P=.58; P=.38) and COMMED study (P=.87; P=.56) showed no significant change over the 8-week intervention period. There was no significant change in physical activity within all studies (P=.31). Only in the HELP study, the physical activity level increased steadily over the period analyzed (P=.045). Overall, 17 participants (85%, 17/20) felt secure and were not scared of injury, with no major differences in the subtrials. CONCLUSIONS: The universal use of the Web-based intervention appears to be applicable across the heterogonous collectives of our study patients with regard to age and disease. Although the development of physical activity shows only moderate improvements, flexible communication and tailored support could be easily integrated into patients' daily routine. TRIAL REGISTRATION: iPEP study: ClinicalTrials.gov NCT02478996; https://clinicaltrials.gov/ct2/show/NCT02478996 (Archived by WebCite at http://www.webcitation.org/6zL1UmHaW); HELP study: ClinicalTrials.gov NCT02526732; http://www.webcitation.org/6zJjX7d6K (Archived by WebCite at http://www.webcitation.org/6Nch4ldcL); EXDEP study: ClinicalTrials.gov NCT02874833; https://clinicaltrials.gov/ct2/show/NCT02874833 (Archived by WebCite at http://www.webcitation.org/6zJjj7FuA).
- Date of acceptance
- 2018
- Autoren
- Daniel Pfirrmann
- Nils Haller
- Yvonne Huber
- Patrick Jung
- Klaus Lieb
- Ines Gockel
- Krystyna Poplawska
- Jörn Markus Schattenberg
- Perikles Simon
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/29789277
- DOI
- 10.2196/resprot.8607
- Externe Identifier
- PubMed Central ID: PMC5989063
- ISSN
- 1929-0748
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- JMIR Res Protoc
- Schlüsselwörter
- cystic fibrosis
- depression
- eHealth
- esophageal cancer
- exercise
- nonalcoholic fatty liver disease
- Sprache
- eng
- Country
- Canada
- Paginierung
- e106
- PII
- v7i5e106
- Datum der Veröffentlichung
- 2018
- Status
- Published online
- Titel
- Applicability of a Web-Based, Individualized Exercise Intervention in Patients With Liver Disease, Cystic Fibrosis, Esophageal Cancer, and Psychiatric Disorders: Process Evaluation of 4 Ongoing Clinical Trials.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 7
Data source: PubMed
- Author's licence
- CC-BY
- Autoren
- Daniel Pfirrmann
- Nils Haller
- Yvonne Huber
- Patrick Jung
- Klaus Lieb
- Ines Gockel
- Krystyna Poplawska
- Jörn Schattenberg
- Perikles Simon
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- JGU-Publikationen
- Resource version
- Published version
- DOI
- 10.2196/resprot.8607
- Funding acknowledgements
- DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 1929-0748
- Ausgabe der Veröffentlichung
- 5
- Zeitschrift
- Journal of medical internet research : Research Protocols
- Schlüsselwörter
- 796 Sport
- 796 Athletic and outdoor sports and games
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- e106
- Datum der Veröffentlichung
- 2018
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/388
- Herausgeber
- s.n.
- Herausgeber URL
- http://dx.doi.org/10.2196/resprot.8607
- Datum der Datenerfassung
- 2018
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2018
- Zugang
- Public
- Titel
- Applicability of a web-based, individualized exercise intervention in patients with liver disease, cystic fibrosis, esophageal cancer, and psychiatric disorders : process evaluation of 4 ongoing clinical trials
- Ausgabe der Zeitschrift
- 7
Files
58369.pdf
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