Organizational unit: Institut für Pharmazeutische und Biomedizinische Wissenschaften / Data source: PubMed and OPENSCIENCE.UB - Universitätsbibliographie Search Results

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1. Identification of a potential allosteric site of Golgi α-mannosidase II using computer-aided drug design

Autoren:: Irsheid, Lina; Wehler, Thomas; Borek, Christoph; Kiefer, Werner; Brenk, Ruth; Ortiz-Soto, Maria Elena; Seibel, Juergen; Schirmeister, Tanja
Editoren:: Silman, Israel
Veröffentlichungsdatum:: 2019
Type:: Journal article

2. A competition smFRET assay to study ligand-induced conformational changes of the dengue virus protease

Autoren:: Maus, Hannah; Hinze, Gerald; Hammerschmidt, Stefan Josef; Basche, Thomas; Schirmeister, Tanja
Veröffentlichungsdatum:: 2023
Type:: Journal article

3. Subnanomolar Cathepsin S Inhibitors with High Selectivity: Optimizing Covalent Reversible α-Fluorovinylsulfones and α-Sulfonates as Potential Immunomodulators in Cancer

Autoren:: Fuchs, Natalie; Meta, Mergim; Lantzberg, Bellinda; Bros, Matthias; Ling Kuan, Seah; Weil, Tanja; Schirmeister, Tanja
Veröffentlichungsdatum:: 2023
Type:: Journal article

4. In-Depth Immune-Oncology Studies of the Tumor Microenvironment in a Humanized Melanoma Mouse Model

Autoren:: Schupp, Jonathan; Christians, Arne; Zimmer, Niklas; Gleue, Lukas; Jonuleit, Helmut; Helm, Mark; Tuettenberg, Andrea
Veröffentlichungsdatum:: 2021
Type:: Journal article

5. Drug repurposing using transcriptome sequencing and virtual drug screening in a patient with glioblastoma

Autoren:: Saeed, Mohamed EM; Kadioglu, Onat; Greten, Henry Johannes; Yildirim, Adem; Mayr, Katharina; Wenz, Frederik; Giordano, Frank A; Efferth, Thomas
Veröffentlichungsdatum:: 2021
Type:: Journal article

6. Shikonin Inhibits Cell Growth of Sunitinib-Resistant Renal Cell Carcinoma by Activating the Necrosome Complex and Inhibiting the AKT/mTOR Signaling Pathway

Autoren:: Markowitsch, Sascha D; Vakhrusheva, Olesya; Schupp, Patricia; Akele, Yasminn; Kitanovic, Jovana; Slade, Kimberly S; Efferth, Thomas; Thomas, Anita; Tsaur, Igor; Mager, Rene; Haferkamp, Axel; Juengel, Eva
Veröffentlichungsdatum:: 2022
Type:: Journal article

7. Chemical Space Virtual Screening against Hard-to-Drug RNA Methyltransferases DNMT2 and NSUN6

Autoren:: Zimmermann, Robert A; Fischer, Tim R; Schwickert, Marvin; Nidoieva, Zarina; Schirmeister, Tanja; Kersten, Christian
Veröffentlichungsdatum:: 2023
Type:: Journal article

8. Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation

Autoren:: Kellner, Stefanie; Kollar, Laura Bettina; Ochel, Antonia; Ghate, Manjunath; Helm, Mark
Editoren:: Meijler, Michael M
Veröffentlichungsdatum:: 2013
Type:: Journal article

9. Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells

Autoren:: Abdelfatah, Sara; Nass, Janine; Knorz, Caroline; Klauck, Sabine M; Kuepper, Jan-Heiner; Efferth, Thomas
Veröffentlichungsdatum:: 2022
Type:: Journal article

10. Collateral Sensitivity of Parthenolide via NF-κB and HIF-α Inhibition and Epigenetic Changes in Drug-Resistant Cancer Cell Lines

Autoren:: Dawood, Mona; Ooko, Edna; Efferth, Thomas
Veröffentlichungsdatum:: 2019
Type:: Journal article