Phytotoxic dioxolanone-type secondary metabolites from Guignardia bidwellii

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Iris Buckel
  • Daniel Molitor
  • Johannes Liermann
  • Louis P Sandjo
  • Beate Berkelmann-Loehnertz
  • Till Opatz
  • Eckhard Thines
Sammlungen
  • metadata
ISSN
0031-9422
Zeitschrift
Phytochemistry
Schlüsselwörter
  • 540 Chemie
  • 540 Chemistry and allied sciences
Sprache
eng
Paginierung
Seiten: 96 - 103
Datum der Veröffentlichung
2013
Herausgeber
Elsevier
Herausgeber URL
http://dx.doi.org/10.1016/j.phytochem.2013.01.004
Datum der Datenerfassung
2020
Datum, an dem der Datensatz öffentlich gemacht wurde
2020
Zugang
Public
Titel
Phytotoxic dioxolanone-type secondary metabolites from Guignardia bidwellii
Ausgabe der Zeitschrift
89

Datenquelle: METADATA.UB

Andere Metadatenquellen:
Autoren
  • Iris Buckel
  • Daniel Molitor
  • Johannes C Liermann
  • Louis P Sandjo
  • Beate Berkelmann-Loehnertz
  • Till Opatz
  • Eckhard Thines
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000318133800012&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/j.phytochem.2013.01.004
eISSN
1873-3700
Externe Identifier
  • Clarivate Analytics Document Solution ID: 133JD
  • PubMed Identifier: 23406659
ISSN
0031-9422
Zeitschrift
PHYTOCHEMISTRY
Schlüsselwörter
  • Guignardia bidwellii
  • Botryosphaeriaceae
  • Vitis vinifera (cv. Riesling)
  • Vitaceae
  • Grape black rot
  • Phytotoxins
  • Dioxolanone
  • Guignardic acid
  • Phenguignardic acid
Paginierung
96 - 103
Datum der Veröffentlichung
2013
Status
Published
Titel
Phytotoxic dioxolanone-type secondary metabolites from <i>Guignardia bidwellii</i>
Sub types
  • Article
Ausgabe der Zeitschrift
89

Datenquelle: Web of Science (Lite)

Autoren
  • Iris Buckel
  • Daniel Molitor
  • Johannes C Liermann
  • Louis P Sandjo
  • Beate Berkelmann-Löhnertz
  • Till Opatz
  • Eckhard Thines
DOI
10.1016/j.phytochem.2013.01.004
ISSN
0031-9422
Zeitschrift
Phytochemistry
Sprache
en
Paginierung
96 - 103
Datum der Veröffentlichung
2013
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/j.phytochem.2013.01.004
Datum der Datenerfassung
2020
Titel
Phytotoxic dioxolanone-type secondary metabolites from Guignardia bidwellii
Ausgabe der Zeitschrift
89

Datenquelle: Crossref

Abstract
Phenguignardic acid was recently described as a phytotoxic secondary metabolite from submerged cultures of the grape black rot fungus Guignardia bidwellii. Since the production rate of this natural product in submerged culture is very low, fermentation optimisation was carried out. The optimisation of cultivation conditions led to the identification of seven secondary metabolites, structurally related to guignardic acid, a known secondary metabolite from Guignardia species containing a dioxolanone moiety. All metabolites presented here have not been described to date and are presumably biosynthesised via deamination products of amino acids, such as phenylalanine, valine, tyrosine, and alanine. Four of the seven compounds showed phytotoxic activity. Based on the structures determined by NMR spectroscopy a preliminary structure activity relationship indicated a free carboxyl group as presumably required for the phytotoxic activity.
Addresses
  • Institute of Biotechnology and Drug Research, Erwin-Schrödinger-Strasse 56, D-67663 Kaiserslautern, Germany. buckel@ibwf.de
Autoren
  • Iris Buckel
  • Daniel Molitor
  • Johannes C Liermann
  • Louis P Sandjo
  • Beate Berkelmann-Löhnertz
  • Till Opatz
  • Eckhard Thines
DOI
10.1016/j.phytochem.2013.01.004
eISSN
1873-3700
Externe Identifier
  • PubMed Identifier: 23406659
Open access
false
ISSN
0031-9422
Zeitschrift
Phytochemistry
Schlüsselwörter
  • Ascomycota
  • Vitis
  • Dioxolanes
  • Temperature
  • Fermentation
  • Hydrogen-Ion Concentration
Sprache
eng
Medium
Print-Electronic
Online publication date
2013
Paginierung
96 - 103
Datum der Veröffentlichung
2013
Status
Published
Datum der Datenerfassung
2013
Titel
Phytotoxic dioxolanone-type secondary metabolites from Guignardia bidwellii.
Sub types
  • Research Support, Non-U.S. Gov't
  • Journal Article
Ausgabe der Zeitschrift
89

Datenquelle: Europe PubMed Central

Abstract
Phenguignardic acid was recently described as a phytotoxic secondary metabolite from submerged cultures of the grape black rot fungus Guignardia bidwellii. Since the production rate of this natural product in submerged culture is very low, fermentation optimisation was carried out. The optimisation of cultivation conditions led to the identification of seven secondary metabolites, structurally related to guignardic acid, a known secondary metabolite from Guignardia species containing a dioxolanone moiety. All metabolites presented here have not been described to date and are presumably biosynthesised via deamination products of amino acids, such as phenylalanine, valine, tyrosine, and alanine. Four of the seven compounds showed phytotoxic activity. Based on the structures determined by NMR spectroscopy a preliminary structure activity relationship indicated a free carboxyl group as presumably required for the phytotoxic activity.
Date of acceptance
2013
Autoren
  • Iris Buckel
  • Daniel Molitor
  • Johannes C Liermann
  • Louis P Sandjo
  • Beate Berkelmann-Löhnertz
  • Till Opatz
  • Eckhard Thines
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/23406659
DOI
10.1016/j.phytochem.2013.01.004
eISSN
1873-3700
Zeitschrift
Phytochemistry
Schlüsselwörter
  • Ascomycota
  • Dioxolanes
  • Fermentation
  • Hydrogen-Ion Concentration
  • Temperature
  • Vitis
Sprache
eng
Country
England
Paginierung
96 - 103
PII
S0031-9422(13)00026-5
Datum der Veröffentlichung
2013
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2013
Titel
Phytotoxic dioxolanone-type secondary metabolites from Guignardia bidwellii.
Sub types
  • Journal Article
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
89

Datenquelle: PubMed

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