Emotional changes during experimentally induced hypoglycaemia in type 1 diabetes

Autoren

N Hermanns
T Kubiak
B Kulzer
T Haak

Autoren-URL

https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000182789300002&DestLinkType=FullRecord&DestApp=WOS_CPL

DOI

10.1016/S0301-0511(03)00027-9

eISSN

1873-6246

Externe Identifier

Clarivate Analytics Document Solution ID: 677CL
PubMed Identifier: 12706962

ISSN

0301-0511

Ausgabe der Veröffentlichung

1

Zeitschrift

BIOLOGICAL PSYCHOLOGY

Schlüsselwörter

hypoglycaemia
emotion
mood changes
type 1 diabetes
emotional processing

Paginierung

15 - 44

Datum der Veröffentlichung

2003

Status

Published

Titel

Emotional changes during experimentally induced hypoglycaemia in type 1 diabetes

Sub types

Article

Ausgabe der Zeitschrift

63

Datenquelle: Web of Science (Lite)

Autoren

Norbert Hermanns
T Kubiak
B Kulzer
T Haak

DOI

10.1016/s0301-0511(03)00027-9

ISSN

0301-0511

Ausgabe der Veröffentlichung

1

Zeitschrift

Biological Psychology

Sprache

en

Paginierung

15 - 44

Datum der Veröffentlichung

2003

Status

Published

Herausgeber

Elsevier BV

Herausgeber URL

http://dx.doi.org/10.1016/s0301-0511(03)00027-9

Datum der Datenerfassung

2019

Titel

Emotional changes during experimentally induced hypoglycaemia in type 1 diabetes

Ausgabe der Zeitschrift

63

Datenquelle: Crossref

Abstract

Emotional changes during experimentally induced hypoglycaemia in type 1 diabetic patients were investigated using a hyperinsulinaemic glucose clamp. In the experimental group (n=11), blood glucose was stabilised at euglycaemia (5.6 mmol/l, phase 1), then lowered to 2.5 mmol/l (phase 2) and raised to 5.6 mmol/l (phase 3). In the control group (n=11), euglycaemia was maintained during all phases. Hypoglycaemia elicited the expected endocrine, symptomatic and neuroglycopenic effects. During hypoglycaemia negative mood states increased significantly, whereas positive mood states decreased. Hypoglycaemia prolonged rating time of emotional stimuli (drawn from IAPS) significantly. The arousal ratings of the slides were higher during hypoglycaemia. Valence and dominance ratings were not affected. Epinephrine and norepinephrine release correlated with a higher arousal rating and a decrease in positive mood states. Deterioration in neuropsychological tasks correlated with an increase in negative mood states. Experimental induction of hypoglycaemia can offer a new research model to study emotional processes.

Addresses

Research Institute of the Diabetes Academy Mergentheim, P.O. Box 1144, D-97961 Bad Mergentheim, Germany. hermanns@diabetes-zentrum.de

Autoren

Norbert Hermanns
T Kubiak
B Kulzer
T Haak

DOI

10.1016/s0301-0511(03)00027-9

eISSN

1873-6246

Externe Identifier

PubMed Identifier: 12706962

Open access

false

ISSN

0301-0511

Ausgabe der Veröffentlichung

1

Zeitschrift

Biological psychology

Schlüsselwörter

Autonomic Nervous System
Humans
Diabetes Mellitus, Type 1
Hypoglycemia
Epinephrine
Norepinephrine
Photic Stimulation
Cognition Disorders
Mood Disorders
Neuropsychological Tests
Adult
Female
Male

Sprache

eng

Medium

Print

Paginierung

15 - 44

Datum der Veröffentlichung

2003

Status

Published

Datum der Datenerfassung

2003

Titel

Emotional changes during experimentally induced hypoglycaemia in type 1 diabetes.

Sub types

Journal Article

Ausgabe der Zeitschrift

63

Datenquelle: Europe PubMed Central

Abstract

Emotional changes during experimentally induced hypoglycaemia in type 1 diabetic patients were investigated using a hyperinsulinaemic glucose clamp. In the experimental group (n=11), blood glucose was stabilised at euglycaemia (5.6 mmol/l, phase 1), then lowered to 2.5 mmol/l (phase 2) and raised to 5.6 mmol/l (phase 3). In the control group (n=11), euglycaemia was maintained during all phases. Hypoglycaemia elicited the expected endocrine, symptomatic and neuroglycopenic effects. During hypoglycaemia negative mood states increased significantly, whereas positive mood states decreased. Hypoglycaemia prolonged rating time of emotional stimuli (drawn from IAPS) significantly. The arousal ratings of the slides were higher during hypoglycaemia. Valence and dominance ratings were not affected. Epinephrine and norepinephrine release correlated with a higher arousal rating and a decrease in positive mood states. Deterioration in neuropsychological tasks correlated with an increase in negative mood states. Experimental induction of hypoglycaemia can offer a new research model to study emotional processes.

Autoren

Norbert Hermanns
T Kubiak
B Kulzer
T Haak

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/12706962

DOI

10.1016/s0301-0511(03)00027-9

ISSN

0301-0511

Ausgabe der Veröffentlichung

1

Zeitschrift

Biol Psychol

Schlüsselwörter

Adult
Autonomic Nervous System
Cognition Disorders
Diabetes Mellitus, Type 1
Epinephrine
Female
Humans
Hypoglycemia
Male
Mood Disorders
Neuropsychological Tests
Norepinephrine
Photic Stimulation

Sprache

eng

Country

Netherlands

Paginierung

15 - 44

PII

S0301051103000279

Datum der Veröffentlichung

2003

Status

Published

Datum, an dem der Datensatz öffentlich gemacht wurde

2003

Titel

Emotional changes during experimentally induced hypoglycaemia in type 1 diabetes.

Sub types

Journal Article

Ausgabe der Zeitschrift

63

Datenquelle: PubMed

Emotional changes during experimentally induced hypoglycaemia in type 1 diabetes

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