Assessment of hypoglycaemia awareness using continuous glucose monitoring

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Thomas Kubiak
  • Norbert Hermanns
  • HJ Schreckling
  • Bernhard Kulzer
  • Thomas Haak
Sammlungen
  • metadata
ISSN
1464-5491
Ausgabe der Veröffentlichung
5
Zeitschrift
Diabetic medicine
Schlüsselwörter
  • 150 Psychologie
  • 150 Psychology
Sprache
eng
Paginierung
Seiten: 487 - 490
Datum der Veröffentlichung
2004
Herausgeber
Wiley- Blackwell
Herausgeber URL
http://dx.doi.org/10.1111/j.1464-5491.2004.1136.x
Datum der Datenerfassung
2020
Datum, an dem der Datensatz öffentlich gemacht wurde
2020
Zugang
Public
Titel
Assessment of hypoglycaemia awareness using continuous glucose monitoring
Ausgabe der Zeitschrift
21

Datenquelle: METADATA.UB

Andere Metadatenquellen:
Autoren
  • T Kubiak
  • N Hermanns
  • HJ Schreckling
  • B Kulzer
  • T Haak
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000221243700014&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1111/j.1464-5491.2004.1136.x
eISSN
1464-5491
Externe Identifier
  • Clarivate Analytics Document Solution ID: 818KJ
  • PubMed Identifier: 15089796
ISSN
0742-3071
Ausgabe der Veröffentlichung
5
Zeitschrift
DIABETIC MEDICINE
Schlüsselwörter
  • Type 1 diabetes
  • hypoglycaemia
  • hypoglycaemia awareness
  • continuous glucose monitoring
Paginierung
487 - 490
Datum der Veröffentlichung
2004
Status
Published
Titel
Assessment of hypoglycaemia awareness using continuous glucose monitoring
Sub types
  • Article
Ausgabe der Zeitschrift
21

Datenquelle: Web of Science (Lite)

Abstract
<jats:title>Abstract</jats:title><jats:p><jats:bold>Aims </jats:bold> To investigate the possibility of assessing hypoglycaemia awareness in patients with Type 1 diabetes using continuous glucose monitoring.</jats:p><jats:p><jats:bold>Methods </jats:bold> Twenty patients with Type 1 diabetes were investigated. Ten patients with Type 1 diabetes and strongly impaired hypoglycaemia awareness were compared with 10 patients with intact hypoglycaemia awareness regarding quality of hypoglycaemia perception (number of undetected hypoglycaemic episodes per 24 h, glucose level &lt; 3.3 mmol/l). Hypoglycaemia detection was assessed using the event function of the Continuous Glucose Monitoring System (CGMS™; Medtronic MiniMed®, Northridge, CA, USA). Patients were instructed to enter an event upon suspecting being hypoglycaemic.</jats:p><jats:p><jats:bold>Results </jats:bold> Satisfactory CGMS performance could be achieved [mean <jats:italic>r</jats:italic> = 0.893 between calibration measurements and CGMS data, mean absolute difference (MAD) = 20.6%], although artefacts were observable and had to be controlled. Hypoglycaemia unaware patients showed a significantly higher total number of hypoglycaemic episodes (<jats:italic>P</jats:italic> &lt; 0.05), number of undetected hypoglycaemic episodes (<jats:italic>P</jats:italic> &lt; 0.01), and mean glucose levels (<jats:italic>P</jats:italic> &lt; 0.05). Even in aware patients, undetected hypoglycaemia was observable. No significant differences regarding occurrence of nocturnal hypoglycaemia were observable.</jats:p><jats:p><jats:bold>Conclusions </jats:bold> The possibility of direct assessment of hypoglycaemia awareness using continuous glucose monitoring was demonstrated. Its application in clinical practice could be of use for assessing hypoglycaemia perception and evaluating the impact of treatment changes on hypoglycaemia awareness.</jats:p>
Autoren
  • T Kubiak
  • N Hermanns
  • HJ Schreckling
  • B Kulzer
  • T Haak
DOI
10.1111/j.1464-5491.2004.1136.x
eISSN
1464-5491
ISSN
0742-3071
Ausgabe der Veröffentlichung
5
Zeitschrift
Diabetic Medicine
Sprache
en
Online publication date
2004
Paginierung
487 - 490
Datum der Veröffentlichung
2004
Status
Published
Herausgeber
Wiley
Herausgeber URL
http://dx.doi.org/10.1111/j.1464-5491.2004.1136.x
Datum der Datenerfassung
2023
Titel
Assessment of hypoglycaemia awareness using continuous glucose monitoring
Ausgabe der Zeitschrift
21

Datenquelle: Crossref

Abstract
<h4>Aims</h4>To investigate the possibility of assessing hypoglycaemia awareness in patients with Type 1 diabetes using continuous glucose monitoring.<h4>Methods</h4>Twenty patients with Type 1 diabetes were investigated. Ten patients with Type 1 diabetes and strongly impaired hypoglycaemia awareness were compared with 10 patients with intact hypoglycaemia awareness regarding quality of hypoglycaemia perception (number of undetected hypoglycaemic episodes per 24 h, glucose level < 3.3 mmol/l). Hypoglycaemia detection was assessed using the event function of the Continuous Glucose Monitoring System (CGMS; Medtronic MiniMed, Northridge, CA, USA). Patients were instructed to enter an event upon suspecting being hypoglycaemic.<h4>Results</h4>Satisfactory CGMS performance could be achieved [mean r = 0.893 between calibration measurements and CGMS data, mean absolute difference (MAD) = 20.6%], although artefacts were observable and had to be controlled. Hypoglycaemia unaware patients showed a significantly higher total number of hypoglycaemic episodes (P < 0.05), number of undetected hypoglycaemic episodes (P < 0.01), and mean glucose levels (P < 0.05). Even in aware patients, undetected hypoglycaemia was observable. No significant differences regarding occurrence of nocturnal hypoglycaemia were observable.<h4>Conclusions</h4>The possibility of direct assessment of hypoglycaemia awareness using continuous glucose monitoring was demonstrated. Its application in clinical practice could be of use for assessing hypoglycaemia perception and evaluating the impact of treatment changes on hypoglycaemia awareness.
Addresses
  • Research Institute of the Diabetes Academy Mergentheim, Th-Klotzbuecher-Strasse-12, D-97980 Bad Mergentheim, Germany. kubiak@diabetes-zentrum.de
Autoren
  • T Kubiak
  • N Hermanns
  • HJ Schreckling
  • B Kulzer
  • T Haak
DOI
10.1111/j.1464-5491.2004.1136.x
eISSN
1464-5491
Externe Identifier
  • PubMed Identifier: 15089796
Open access
false
ISSN
0742-3071
Ausgabe der Veröffentlichung
5
Zeitschrift
Diabetic medicine : a journal of the British Diabetic Association
Schlüsselwörter
  • Humans
  • Diabetes Mellitus, Type 1
  • Hypoglycemia
  • Insulin
  • Hypoglycemic Agents
  • Blood Glucose Self-Monitoring
  • Pilot Projects
  • Awareness
  • Adult
  • Middle Aged
  • Female
  • Male
Sprache
eng
Medium
Print
Paginierung
487 - 490
Datum der Veröffentlichung
2004
Status
Published
Datum der Datenerfassung
2004
Titel
Assessment of hypoglycaemia awareness using continuous glucose monitoring.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
21

Datenquelle: Europe PubMed Central

Abstract
AIMS: To investigate the possibility of assessing hypoglycaemia awareness in patients with Type 1 diabetes using continuous glucose monitoring. METHODS: Twenty patients with Type 1 diabetes were investigated. Ten patients with Type 1 diabetes and strongly impaired hypoglycaemia awareness were compared with 10 patients with intact hypoglycaemia awareness regarding quality of hypoglycaemia perception (number of undetected hypoglycaemic episodes per 24 h, glucose level < 3.3 mmol/l). Hypoglycaemia detection was assessed using the event function of the Continuous Glucose Monitoring System (CGMS; Medtronic MiniMed, Northridge, CA, USA). Patients were instructed to enter an event upon suspecting being hypoglycaemic. RESULTS: Satisfactory CGMS performance could be achieved [mean r = 0.893 between calibration measurements and CGMS data, mean absolute difference (MAD) = 20.6%], although artefacts were observable and had to be controlled. Hypoglycaemia unaware patients showed a significantly higher total number of hypoglycaemic episodes (P < 0.05), number of undetected hypoglycaemic episodes (P < 0.01), and mean glucose levels (P < 0.05). Even in aware patients, undetected hypoglycaemia was observable. No significant differences regarding occurrence of nocturnal hypoglycaemia were observable. CONCLUSIONS: The possibility of direct assessment of hypoglycaemia awareness using continuous glucose monitoring was demonstrated. Its application in clinical practice could be of use for assessing hypoglycaemia perception and evaluating the impact of treatment changes on hypoglycaemia awareness.
Autoren
  • T Kubiak
  • N Hermanns
  • HJ Schreckling
  • B Kulzer
  • T Haak
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/15089796
DOI
10.1111/j.1464-5491.2004.1136.x
ISSN
0742-3071
Ausgabe der Veröffentlichung
5
Zeitschrift
Diabet Med
Schlüsselwörter
  • Adult
  • Awareness
  • Blood Glucose Self-Monitoring
  • Diabetes Mellitus, Type 1
  • Female
  • Humans
  • Hypoglycemia
  • Hypoglycemic Agents
  • Insulin
  • Male
  • Middle Aged
  • Pilot Projects
Sprache
eng
Country
England
Paginierung
487 - 490
PII
DME1136
Datum der Veröffentlichung
2004
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2004
Titel
Assessment of hypoglycaemia awareness using continuous glucose monitoring.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
21

Datenquelle: PubMed

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