Pseudouridine: Still mysterious, but never a fake (uridine)!

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Felix Spenkuch
  • Yuri Motorin
  • Mark Helm
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000350568300007&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.4161/15476286.2014.992278
eISSN
1555-8584
Externe Identifier
  • Clarivate Analytics Document Solution ID: CC7SI
  • PubMed Identifier: 25616362
ISSN
1547-6286
Ausgabe der Veröffentlichung
12
Zeitschrift
RNA BIOLOGY
Schlüsselwörter
  • enzymatic mechanism
  • modified nucleoside
  • pseudouridine
  • regulation
  • rRNA
  • RNA Modification
  • tRNA
  • snRNA
Paginierung
1540 - 1554
Datum der Veröffentlichung
2014
Status
Published
Titel
Pseudouridine: Still mysterious, but never a fake (uridine)!
Sub types
  • Review
Ausgabe der Zeitschrift
11

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Autoren
  • Felix Spenkuch
  • Yuri Motorin
  • Mark Helm
DOI
10.4161/15476286.2014.992278
eISSN
1555-8584
ISSN
1547-6286
Ausgabe der Veröffentlichung
12
Zeitschrift
RNA Biology
Sprache
en
Online publication date
2015
Paginierung
1540 - 1554
Datum der Veröffentlichung
2014
Status
Published
Herausgeber
Informa UK Limited
Herausgeber URL
http://dx.doi.org/10.4161/15476286.2014.992278
Datum der Datenerfassung
2022
Titel
Pseudouridine: Still mysterious, but never a fake (uridine)!
Ausgabe der Zeitschrift
11

Datenquelle: Crossref

Abstract
Pseudouridine (Ψ) is the most abundant of >150 nucleoside modifications in RNA. Although Ψ was discovered as the first modified nucleoside more than half a century ago, neither the enzymatic mechanism of its formation, nor the function of this modification are fully elucidated. We present the consistent picture of Ψ synthases, their substrates and their substrate positions in model organisms of all domains of life as it has emerged to date and point out the challenges that remain concerning higher eukaryotes and the elucidation of the enzymatic mechanism.
Addresses
  • a Institute of Pharmacy and Biochemistry ; Johannes Gutenberg-University of Mainz ; Mainz , Germany.
Autoren
  • Felix Spenkuch
  • Yuri Motorin
  • Mark Helm
DOI
10.4161/15476286.2014.992278
eISSN
1555-8584
Externe Identifier
  • PubMed Identifier: 25616362
  • PubMed Central ID: PMC4615568
Open access
false
ISSN
1547-6286
Ausgabe der Veröffentlichung
12
Zeitschrift
RNA biology
Schlüsselwörter
  • Ribosomes
  • Humans
  • Escherichia coli
  • Saccharomyces cerevisiae
  • Isoenzymes
  • Intramolecular Transferases
  • Ribonucleoproteins, Small Nuclear
  • RNA
  • RNA, Ribosomal
  • RNA, Transfer, Amino Acid-Specific
  • Uridine
  • Pseudouridine
  • RNA Processing, Post-Transcriptional
  • Nucleic Acid Conformation
  • RNA, Mitochondrial
  • RNA, Guide, CRISPR-Cas Systems
Sprache
eng
Medium
Print
Paginierung
1540 - 1554
Datum der Veröffentlichung
2014
Status
Published
Datum der Datenerfassung
2015
Titel
Pseudouridine: still mysterious, but never a fake (uridine)!
Sub types
  • review-article
  • Review
  • Journal Article
Ausgabe der Zeitschrift
11

Files

https://www.tandfonline.com/doi/pdf/10.4161/15476286.2014.992278?needAccess=true https://europepmc.org/articles/PMC4615568?pdf=render

Datenquelle: Europe PubMed Central

Abstract
Pseudouridine (Ψ) is the most abundant of >150 nucleoside modifications in RNA. Although Ψ was discovered as the first modified nucleoside more than half a century ago, neither the enzymatic mechanism of its formation, nor the function of this modification are fully elucidated. We present the consistent picture of Ψ synthases, their substrates and their substrate positions in model organisms of all domains of life as it has emerged to date and point out the challenges that remain concerning higher eukaryotes and the elucidation of the enzymatic mechanism.
Autoren
  • Felix Spenkuch
  • Yuri Motorin
  • Mark Helm
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/25616362
DOI
10.4161/15476286.2014.992278
eISSN
1555-8584
Externe Identifier
  • PubMed Central ID: PMC4615568
Ausgabe der Veröffentlichung
12
Zeitschrift
RNA Biol
Schlüsselwörter
  • E. coli, Escherichia coli
  • H. volcanii, Haloferax volcanii and/or Halobacterium volcanii.
  • Pus, pseudouridine synthase
  • RNA Modification
  • S. cerevisiae, Saccharomyces cerevisiae
  • S. typhimurium, Salmonella typhimurium
  • enzymatic mechanism
  • modified nucleoside
  • pseudouridine
  • rRNA
  • rRNA, ribosomal RNA
  • regulation
  • snRNA
  • snRNA, small nuclear RNA
  • tRNA
  • Ψ, Psi, pseudouridine
  • Escherichia coli
  • Humans
  • Intramolecular Transferases
  • Isoenzymes
  • Nucleic Acid Conformation
  • Pseudouridine
  • RNA
  • RNA Processing, Post-Transcriptional
  • RNA, Mitochondrial
  • RNA, Ribosomal
  • RNA, Transfer, Amino Acid-Specific
  • Ribonucleoproteins, Small Nuclear
  • Ribosomes
  • Saccharomyces cerevisiae
  • Uridine
  • RNA, Guide, CRISPR-Cas Systems
Sprache
eng
Country
United States
Paginierung
1540 - 1554
Datum der Veröffentlichung
2014
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2015
Titel
Pseudouridine: still mysterious, but never a fake (uridine)!
Sub types
  • Journal Article
  • Review
Ausgabe der Zeitschrift
11

Datenquelle: PubMed

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