Three-week sprint interval training (SIT) reduces cell-free DNA and low-frequency fatigue but does not induce VO2max improvement in older men
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Ema Juskeviciute
- Elmo Neuberger
- Nerijus Eimantas
- Tomas Venckunas
- Sigitas Kamandulis
- Perikles Simon
- Marius Brazaitis
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:001110242300001&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1007/s00421-023-05366-2
- eISSN
- 1439-6327
- Externe Identifier
- Clarivate Analytics Document Solution ID: LY9H9
- PubMed Identifier: 38015284
- ISSN
- 1439-6319
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Schlüsselwörter
- Cell-free DNA
- Sprint interval training
- Aging
- Adaptation
- Fatigue
- Paginierung
- 1297 - 1309
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Titel
- Three-week sprint interval training (SIT) reduces cell-free DNA and low-frequency fatigue but does not induce VO2max improvement in older men
- Sub types
- Article
- Ausgabe der Zeitschrift
- 124
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Ema Juškevičiūtė
- Elmo Neuberger
- Nerijus Eimantas
- Tomas Venckunas
- Sigitas Kamandulis
- Perikles Simon
- Marius Brazaitis
- DOI
- 10.1007/s00421-023-05366-2
- eISSN
- 1439-6327
- ISSN
- 1439-6319
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- European Journal of Applied Physiology
- Sprache
- en
- Online publication date
- 2023
- Paginierung
- 1297 - 1309
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1007/s00421-023-05366-2
- Datum der Datenerfassung
- 2024
- Titel
- Three-week sprint interval training (SIT) reduces cell-free DNA and low-frequency fatigue but does not induce VO2max improvement in older men
- Ausgabe der Zeitschrift
- 124
Datenquelle: Crossref
- Abstract
- <h4>Purpose</h4>This study aimed to investigate the impact of sprint interval training (SIT) on both the acute and 3-week modulations of cell-free DNA (cfDNA), as well as its association with neuromuscular fatigue and physical performance in healthy young and old men.<h4>Methods</h4>Ten young (20-25 year old) and nine elderly (63-72 year old) healthy men performed nine SIT sessions consisting of 4-to-6-all-out cycling repetitions of 30 s interspaced with 4-min rest intervals. We compared the maximal voluntary contractions torque, central activation ratio, low-frequency fatigue (LFF), and cfDNA concentrations between the groups before, immediately after, 1 h after, and 24 h after the first and ninth SIT sessions.<h4>Results</h4>The plasma cfDNA levels were increased post-exercise (from 1.4 ± 0.258 to 1.91 ± 0.278 ng/ml (P < 0.01) on a log10 scale), without significant differences between the groups. However, older individuals showed a slight decrease in the baseline cfDNA values, from 1.39 ± 0.176 to 1.29 ± 0.085 ng/ml on a log10 scale, after 3 weeks (P = 0.043). Importantly, the elevation of the post-exercise cfDNA values was correlated with an increase in LFF in both groups. Three weeks of SIT induced an improvement in the recovery of LFF (main session effect, P = 0.0029); however, only the young group showed an increase in aerobic capacity (VO<sub>2max</sub>) (from 40.8 ± 6.74 to 43.0 ± 5.80 ml/kg/min, P = 0.0039).<h4>Conclusion</h4>Three weeks of SIT diminished the baseline cfDNA values in the old group, together with an improvement in the recovery of LFF. However, VO<sub>2max</sub> was increased only in the young group.
- Addresses
- Institute of Sport Science and Innovations, Lithuanian Sports University, Kaunas, Lithuania. emajus@stud.lsu.lt.
- Autoren
- Ema Juškevičiūtė
- Elmo Neuberger
- Nerijus Eimantas
- Tomas Venckunas
- Sigitas Kamandulis
- Perikles Simon
- Marius Brazaitis
- DOI
- 10.1007/s00421-023-05366-2
- eISSN
- 1439-6327
- Externe Identifier
- PubMed Identifier: 38015284
- Open access
- false
- ISSN
- 1439-6319
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- European journal of applied physiology
- Schlüsselwörter
- Humans
- Adaptation, Physiological
- Oxygen Consumption
- Exercise Tolerance
- Adult
- Aged
- Middle Aged
- Male
- Young Adult
- High-Intensity Interval Training
- Cell-Free Nucleic Acids
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2023
- Paginierung
- 1297 - 1309
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Datum der Datenerfassung
- 2023
- Titel
- Three-week sprint interval training (SIT) reduces cell-free DNA and low-frequency fatigue but does not induce VO2max improvement in older men.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 124
Datenquelle: Europe PubMed Central
- Abstract
- PURPOSE: This study aimed to investigate the impact of sprint interval training (SIT) on both the acute and 3-week modulations of cell-free DNA (cfDNA), as well as its association with neuromuscular fatigue and physical performance in healthy young and old men. METHODS: Ten young (20-25 year old) and nine elderly (63-72 year old) healthy men performed nine SIT sessions consisting of 4-to-6-all-out cycling repetitions of 30 s interspaced with 4-min rest intervals. We compared the maximal voluntary contractions torque, central activation ratio, low-frequency fatigue (LFF), and cfDNA concentrations between the groups before, immediately after, 1 h after, and 24 h after the first and ninth SIT sessions. RESULTS: The plasma cfDNA levels were increased post-exercise (from 1.4 ± 0.258 to 1.91 ± 0.278 ng/ml (P < 0.01) on a log10 scale), without significant differences between the groups. However, older individuals showed a slight decrease in the baseline cfDNA values, from 1.39 ± 0.176 to 1.29 ± 0.085 ng/ml on a log10 scale, after 3 weeks (P = 0.043). Importantly, the elevation of the post-exercise cfDNA values was correlated with an increase in LFF in both groups. Three weeks of SIT induced an improvement in the recovery of LFF (main session effect, P = 0.0029); however, only the young group showed an increase in aerobic capacity (VO2max) (from 40.8 ± 6.74 to 43.0 ± 5.80 ml/kg/min, P = 0.0039). CONCLUSION: Three weeks of SIT diminished the baseline cfDNA values in the old group, together with an improvement in the recovery of LFF. However, VO2max was increased only in the young group.
- Date of acceptance
- 2023
- Autoren
- Ema Juškevičiūtė
- Elmo Neuberger
- Nerijus Eimantas
- Tomas Venckunas
- Sigitas Kamandulis
- Perikles Simon
- Marius Brazaitis
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/38015284
- DOI
- 10.1007/s00421-023-05366-2
- eISSN
- 1439-6327
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Eur J Appl Physiol
- Schlüsselwörter
- Adaptation
- Aging
- Cell-free DNA
- Fatigue
- Sprint interval training
- Male
- Humans
- Aged
- Young Adult
- Adult
- Middle Aged
- High-Intensity Interval Training
- Oxygen Consumption
- Adaptation, Physiological
- Exercise Tolerance
- Cell-Free Nucleic Acids
- Sprache
- eng
- Country
- Germany
- Paginierung
- 1297 - 1309
- PII
- 10.1007/s00421-023-05366-2
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2024
- Titel
- Three-week sprint interval training (SIT) reduces cell-free DNA and low-frequency fatigue but does not induce VO2max improvement in older men.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 124
Datenquelle: PubMed
- Beziehungen:
- Eigentum von