Effects of Aerobic-, Anaerobic- and Combined-Based Exercises on Plasma Oxidative Stress Biomarkers in Healthy Untrained Young Adults

Abstract

Currently, it is well accepted that physical exercise-induced oxidative stress may damage biological structures and impair cellular functions. However, it is still unclear which type of exercise results in the greatest oxidative stress responses among a healthy untrained population. The aim of the present study was to compare the acute oxidative stress response (i.e., 0 to 20 min) following different types of exercise (anaerobic, aerobic, and combined). Ten healthy, untrained males (19.5 ± 1.7 years) performed three randomized exercise bouts: anaerobic (30 s Wingate test), aerobic (30 min at 60% maximal aerobic power (MAP)) or combined (anaerobic and aerobic). Venous blood samples were collected before, as well as at 0 (P0), 5 (P5), 10 (P10), and 20 (P20) min after each session. Rates of malondialdehyde (MDA) and antioxidant activities (i.e., glutathione peroxidase (GPX), superoxide dismutase (SOD), glutathione reductase (GR), α-tocopherol, and total antioxidant status (TAS)) were assessed. Independent of exercise type, plasma MDA, GPX, SOD, and GR contents increased above baseline, whereas plasma α-tocopherol decreased under baseline after the test sessions (p < 0.05). Aerobic and anaerobic exercises generated faster responses (at P0) when compared to the combined exercise (P5 to P10) for the majority of the tested parameters. Plasma TAS content only increased following the aerobic exercise at P10 (p = 0.03). Five to twenty-minutes post exercise, the highest MDA response was registered in the aerobic condition, and the highest GPX and SOD responses were recorded in the anaerobic (at P5) and aerobic (at P20) conditions (p < 0.05). In conclusion, aerobic, anaerobic, or combined exercises have the potential to acutely increase oxidative stress and antioxidant activities, but with different responses magnitude. These findings confirm that oxidative stress response seems to be dependent on the intensity and the duration of the physical exercise and may help in understanding how varying exercise bouts influence the degree of oxidative stress among healthy untrained young adults.

Autoren

Achraf Ammar
Khaled Trabelsi
Omar Boukhris
Jordan Glenn
Nick Bott
Liwa Masmoudi
Ahmed Hakim
Hamdi Chtourou
Tarak Driss
Anita Hoekelmann
Kais El Abed

DOI

10.3390/ijerph17072601

eISSN

1660-4601

Ausgabe der Veröffentlichung

7

Zeitschrift

International Journal of Environmental Research and Public Health

Sprache

en

Online publication date

2020

Paginierung

2601 - 2601

Status

Published online

Herausgeber

MDPI AG

Herausgeber URL

http://dx.doi.org/10.3390/ijerph17072601

Datum der Datenerfassung

2020

Titel

Effects of Aerobic-, Anaerobic- and Combined-Based Exercises on Plasma Oxidative Stress Biomarkers in Healthy Untrained Young Adults

Ausgabe der Zeitschrift

17

Datenquelle: Crossref

Abstract

Currently, it is well accepted that physical exercise-induced oxidative stress may damage biological structures and impair cellular functions. However, it is still unclear which type of exercise results in the greatest oxidative stress responses among a healthy untrained population. The aim of the present study was to compare the acute oxidative stress response (i.e., 0 to 20 min) following different types of exercise (anaerobic, aerobic, and combined). Ten healthy, untrained males (19.5 ± 1.7 years) performed three randomized exercise bouts: anaerobic (30 s Wingate test), aerobic (30 min at 60% maximal aerobic power (MAP)) or combined (anaerobic and aerobic). Venous blood samples were collected before, as well as at 0 (P0), 5 (P5), 10 (P10), and 20 (P20) min after each session. Rates of malondialdehyde (MDA) and antioxidant activities (i.e., glutathione peroxidase (GPX), superoxide dismutase (SOD), glutathione reductase (GR), α-tocopherol, and total antioxidant status (TAS)) were assessed. Independent of exercise type, plasma MDA, GPX, SOD, and GR contents increased above baseline, whereas plasma α-tocopherol decreased under baseline after the test sessions (p < 0.05). Aerobic and anaerobic exercises generated faster responses (at P0) when compared to the combined exercise (P5 to P10) for the majority of the tested parameters. Plasma TAS content only increased following the aerobic exercise at P10 (p = 0.03). Five to twenty-minutes post exercise, the highest MDA response was registered in the aerobic condition, and the highest GPX and SOD responses were recorded in the anaerobic (at P5) and aerobic (at P20) conditions (p < 0.05). In conclusion, aerobic, anaerobic, or combined exercises have the potential to acutely increase oxidative stress and antioxidant activities, but with different responses magnitude. These findings confirm that oxidative stress response seems to be dependent on the intensity and the duration of the physical exercise and may help in understanding how varying exercise bouts influence the degree of oxidative stress among healthy untrained young adults.

Addresses

Institute of Sport Science, Otto-von-Guericke-University Magdeburg, 39106 Magdeburg, Germany.

Autoren

Achraf Ammar
Khaled Trabelsi
Omar Boukhris
Jordan M Glenn
Nick Bott
Liwa Masmoudi
Ahmed Hakim
Hamdi Chtourou
Tarak Driss
Anita Hoekelmann
Kais El Abed

DOI

10.3390/ijerph17072601

eISSN

1660-4601

Externe Identifier

PubMed Identifier: 32290148
PubMed Central ID: PMC7178085

Open access

true

ISSN

1661-7827

Ausgabe der Veröffentlichung

7

Zeitschrift

International journal of environmental research and public health

Schlüsselwörter

Humans
Malondialdehyde
Glutathione Peroxidase
Superoxide Dismutase
Antioxidants
Exercise
Anaerobiosis
Oxidative Stress
Male
Young Adult
Biomarkers

Sprache

eng

Medium

Electronic

Online publication date

2020

Open access status

Open Access

Paginierung

E2601

Datum der Veröffentlichung

2020

Status

Published

Publisher licence

CC BY

Datum der Datenerfassung

2020

Titel

Effects of Aerobic-, Anaerobic- and Combined-Based Exercises on Plasma Oxidative Stress Biomarkers in Healthy Untrained Young Adults.

Sub types

research-article
Randomized Controlled Trial
Journal Article

Ausgabe der Zeitschrift

17

Files

https://www.mdpi.com/1660-4601/17/7/2601/pdf?version=1586934575 https://europepmc.org/articles/PMC7178085?pdf=render

Datenquelle: Europe PubMed Central

Abstract

Currently, it is well accepted that physical exercise-induced oxidative stress may damage biological structures and impair cellular functions. However, it is still unclear which type of exercise results in the greatest oxidative stress responses among a healthy untrained population. The aim of the present study was to compare the acute oxidative stress response (i.e., 0 to 20 min) following different types of exercise (anaerobic, aerobic, and combined). Ten healthy, untrained males (19.5 ± 1.7 years) performed three randomized exercise bouts: anaerobic (30 s Wingate test), aerobic (30 min at 60% maximal aerobic power (MAP)) or combined (anaerobic and aerobic). Venous blood samples were collected before, as well as at 0 (P0), 5 (P5), 10 (P10), and 20 (P20) min after each session. Rates of malondialdehyde (MDA) and antioxidant activities (i.e., glutathione peroxidase (GPX), superoxide dismutase (SOD), glutathione reductase (GR), α-tocopherol, and total antioxidant status (TAS)) were assessed. Independent of exercise type, plasma MDA, GPX, SOD, and GR contents increased above baseline, whereas plasma α-tocopherol decreased under baseline after the test sessions (p < 0.05). Aerobic and anaerobic exercises generated faster responses (at P0) when compared to the combined exercise (P5 to P10) for the majority of the tested parameters. Plasma TAS content only increased following the aerobic exercise at P10 (p = 0.03). Five to twenty-minutes post exercise, the highest MDA response was registered in the aerobic condition, and the highest GPX and SOD responses were recorded in the anaerobic (at P5) and aerobic (at P20) conditions (p < 0.05). In conclusion, aerobic, anaerobic, or combined exercises have the potential to acutely increase oxidative stress and antioxidant activities, but with different responses magnitude. These findings confirm that oxidative stress response seems to be dependent on the intensity and the duration of the physical exercise and may help in understanding how varying exercise bouts influence the degree of oxidative stress among healthy untrained young adults.

Date of acceptance

2020

Autoren

Achraf Ammar
Khaled Trabelsi
Omar Boukhris
Jordan M Glenn
Nick Bott
Liwa Masmoudi
Ahmed Hakim
Hamdi Chtourou
Tarak Driss
Anita Hoekelmann
Kais El Abed

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/32290148

DOI

10.3390/ijerph17072601

eISSN

1660-4601

Externe Identifier

PubMed Central ID: PMC7178085

Ausgabe der Veröffentlichung

7

Zeitschrift

Int J Environ Res Public Health

Schlüsselwörter

anaerobic
antioxidant
physical exercise
physiological responses
redox status
untrained healthy young adults
Anaerobiosis
Antioxidants
Biomarkers
Exercise
Glutathione Peroxidase
Humans
Male
Malondialdehyde
Oxidative Stress
Superoxide Dismutase
Young Adult

Sprache

eng

Country

Switzerland

PII

ijerph17072601

Datum der Veröffentlichung

2020

Status

Published online

Datum, an dem der Datensatz öffentlich gemacht wurde

2020

Titel

Effects of Aerobic-, Anaerobic- and Combined-Based Exercises on Plasma Oxidative Stress Biomarkers in Healthy Untrained Young Adults.

Sub types

Journal Article
Randomized Controlled Trial

Ausgabe der Zeitschrift

17

Datenquelle: PubMed

Effects of Aerobic-, Anaerobic- and Combined-Based Exercises on Plasma Oxidative Stress Biomarkers in Healthy Untrained Young Adults

Files

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