Acute exposure to simulated nocturnal traffic noise and cardiovascular complications and sleep disturbance—results from a pooled analysis of human field studies

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Abstract
<jats:title>Abstract</jats:title><jats:sec> <jats:title>Objectives</jats:title> <jats:p>A series of human field studies demonstrated that acute exposure to simulated nocturnal traffic noise is associated with cardiovascular complications and sleep disturbance, including endothelial dysfunction, increased blood pressure, and impaired sleep quality. A pooled analysis of these results remains to be established and is of tremendous interest to consolidate scientific knowledge.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>We analyzed data from four randomized crossover studies (published between 2013 to 2021 and conducted at the University Medical Center Mainz, Germany). A total of 275 subjects (40.4% women, mean age 43.03 years) were each exposed to one control scenario (regular background noise) and at least to one traffic noise scenario (60 aircraft or train noise events) in their homes during nighttime. After each night, the subjects visited the study center for comprehensive cardiovascular function assessment, including the measurement of endothelial function and hemodynamic and biochemical parameters, as well as sleep-related variables.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The pooled analysis revealed a significantly impaired endothelial function when comparing the two different noise sequences (0–60 vs. 60–0 simulated noise events, mean difference in flow-mediated dilation −2.00%, 95% CI −2.32; −1.68, <jats:italic>p</jats:italic> &lt; 0.0001). In concordance, mean arterial pressure was significantly increased after traffic noise exposure (mean difference 2.50 mmHg, 95% CI 0.54; 4.45, <jats:italic>p</jats:italic> = 0.013). Self-reported sleep quality, the restfulness of sleep, and feeling in the morning were significantly impaired after traffic noise exposure (all <jats:italic>p</jats:italic> &lt; 0.0001).</jats:p> </jats:sec><jats:sec> <jats:title>Discussion</jats:title> <jats:p>Acute exposure to simulated nocturnal traffic noise is associated with endothelial dysfunction, increased mean arterial pressure, and sleep disturbance.</jats:p> </jats:sec>
Autoren
  • Omar Hahad
  • Frank P Schmidt
  • Jonas Hübner
  • Patrick Foos
  • Sadeer Al-Kindi
  • Volker H Schmitt
  • Lukas Hobohm
  • Karsten Keller
  • Christina Große-Dresselhaus
  • Julian Schmeißer
  • Franziska Koppe-Schmeißer
  • Markus Vosseler
  • Donya Gilan
  • Andreas Schulz
  • Julian Chalabi
  • Philipp S Wild
  • Andreas Daiber
  • Johannes Herzog
  • Thomas Münzel
DOI
10.1007/s00392-023-02297-y
eISSN
1861-0692
ISSN
1861-0684
Ausgabe der Veröffentlichung
11
Zeitschrift
Clinical Research in Cardiology
Sprache
en
Online publication date
2023
Paginierung
1690 - 1698
Datum der Veröffentlichung
2023
Status
Published
Herausgeber
Springer Science and Business Media LLC
Herausgeber URL
http://dx.doi.org/10.1007/s00392-023-02297-y
Datum der Datenerfassung
2023
Titel
Acute exposure to simulated nocturnal traffic noise and cardiovascular complications and sleep disturbance—results from a pooled analysis of human field studies
Ausgabe der Zeitschrift
112

Datenquelle: Crossref

Andere Metadatenquellen:
Author's licence
CC-BY
Autoren
  • Omar Hahad
  • Frank P Schmidt
  • Jonas Hübner
  • Patrick Foos
  • Sadeer Al-Kindi
  • Volker H Schmitt
  • Lukas Hobohm
  • Karsten Keller
  • Christina Große-Dresselhaus
  • Julian Schmeißer
  • Franziska Koppe-Schmeißer
  • Markus Vosseler
  • Donya Gilan
  • Andreas Schulz
  • Julian Chalabi
  • Philipp S Wild
  • Andreas Daiber
  • Johannes Herzog
  • Thomas Münzel
Hosting institution
Universitätsbibliothek Mainz
Sammlungen
  • DFG-491381577-H
Resource version
Published version
DOI
10.1007/s00392-023-02297-y
File(s) embargoed
false
Open access
true
ISSN
1861-0692
Zeitschrift
Clinical research in cardiology
Schlüsselwörter
  • 610 Medizin
  • 610 Medical sciences
Sprache
eng
Open access status
Open Access
Paginierung
1690 - 1698
Datum der Veröffentlichung
2023
Public URL
https://openscience.ub.uni-mainz.de/handle/20.500.12030/9883
Herausgeber
Springer
Datum der Datenerfassung
2024
Datum, an dem der Datensatz öffentlich gemacht wurde
2024
Zugang
Public
Titel
Acute exposure to simulated nocturnal traffic noise and cardiovascular complications and sleep disturbance : results from a pooled analysis of human field studies
Ausgabe der Zeitschrift
112

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Datenquelle: OPENSCIENCE.UB

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