Protease detection in the biosensor era: A review
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Pratika Rai
- Sabrina N Hoba
- Celine Buchmann
- Robert J Subirana-Slotos
- Christian Kersten
- Tanja Schirmeister
- Kristina Endres
- Bernd Bufe
- Alexey Tarasov
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:001112281500001&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1016/j.bios.2023.115788
- eISSN
- 1873-4235
- Externe Identifier
- Clarivate Analytics Document Solution ID: Z5DN5
- PubMed Identifier: 37952320
- ISSN
- 0956-5663
- Zeitschrift
- BIOSENSORS & BIOELECTRONICS
- Schlüsselwörter
- Biosensors
- Proteases
- Peptides
- Electrochemical biosensors
- Optical biosensors
- Transducers
- Artikelnummer
- ARTN 115788
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Titel
- Protease detection in the biosensor era: A review
- Sub types
- Review
- Ausgabe der Zeitschrift
- 244
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Pratika Rai
- Sabrina N Hoba
- Celine Buchmann
- Robert J Subirana-Slotos
- Christian Kersten
- Tanja Schirmeister
- Kristina Endres
- Bernd Bufe
- Alexey Tarasov
- DOI
- 10.1016/j.bios.2023.115788
- ISSN
- 0956-5663
- Zeitschrift
- Biosensors and Bioelectronics
- Sprache
- en
- Artikelnummer
- 115788
- Paginierung
- 115788 - 115788
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Herausgeber
- Elsevier BV
- Herausgeber URL
- http://dx.doi.org/10.1016/j.bios.2023.115788
- Datum der Datenerfassung
- 2024
- Titel
- Protease detection in the biosensor era: A review
- Ausgabe der Zeitschrift
- 244
Datenquelle: Crossref
- Abstract
- Proteases have been proposed as potential biomarkers for several pathological conditions including cancers, multiple sclerosis and cardiovascular diseases, due to their ability to break down the components of extracellular matrix and basement membrane. The development of protease biosensors opened up the possibility to investigate the proteolytic activity of dysregulated proteases with higher efficiency over the traditional detection assays due to their quick detection capability, high sensitivity and selectivity, simple instrumentation and cost-effective fabrication processes. In contrast to the recently published review papers that primarily focused on one specific class of proteases or one specific detection method, this review article presents different optical and electrochemical detection methods that can be used to design biosensors for all major protease families. The benefits and drawbacks of various transducer techniques integrated into protease biosensing platforms are analyzed and compared. The main focus is on activity-based biosensors that use peptides as biorecognition elements. The effects of nanomaterials on biosensor performance are also discussed. This review should help readers to select the biosensor that best fits their needs, and contribute to the further development of this research field. Protease biosensors may allow better comprehension of protease overexperession and potentially enable novel devices for point-of-care testing.
- Addresses
- Faculty of Computer Sciences and Microsystems Technology, Kaiserslautern University of Applied Sciences, Amerikastr.1, 66482, Zweibrücken, Germany.
- Autoren
- Pratika Rai
- Sabrina N Hoba
- Celine Buchmann
- Robert J Subirana-Slotos
- Christian Kersten
- Tanja Schirmeister
- Kristina Endres
- Bernd Bufe
- Alexey Tarasov
- DOI
- 10.1016/j.bios.2023.115788
- eISSN
- 1873-4235
- Externe Identifier
- PubMed Identifier: 37952320
- Open access
- false
- ISSN
- 0956-5663
- Zeitschrift
- Biosensors & bioelectronics
- Schlüsselwörter
- Humans
- Peptide Hydrolases
- Endopeptidases
- Biosensing Techniques
- Nanostructures
- Electrochemical Techniques
- Biomarkers
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2023
- Paginierung
- 115788
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Datum der Datenerfassung
- 2023
- Titel
- Protease detection in the biosensor era: A review.
- Sub types
- Review
- Journal Article
- Ausgabe der Zeitschrift
- 244
Datenquelle: Europe PubMed Central
- Abstract
- Proteases have been proposed as potential biomarkers for several pathological conditions including cancers, multiple sclerosis and cardiovascular diseases, due to their ability to break down the components of extracellular matrix and basement membrane. The development of protease biosensors opened up the possibility to investigate the proteolytic activity of dysregulated proteases with higher efficiency over the traditional detection assays due to their quick detection capability, high sensitivity and selectivity, simple instrumentation and cost-effective fabrication processes. In contrast to the recently published review papers that primarily focused on one specific class of proteases or one specific detection method, this review article presents different optical and electrochemical detection methods that can be used to design biosensors for all major protease families. The benefits and drawbacks of various transducer techniques integrated into protease biosensing platforms are analyzed and compared. The main focus is on activity-based biosensors that use peptides as biorecognition elements. The effects of nanomaterials on biosensor performance are also discussed. This review should help readers to select the biosensor that best fits their needs, and contribute to the further development of this research field. Protease biosensors may allow better comprehension of protease overexperession and potentially enable novel devices for point-of-care testing.
- Date of acceptance
- 2023
- Autoren
- Pratika Rai
- Sabrina N Hoba
- Celine Buchmann
- Robert J Subirana-Slotos
- Christian Kersten
- Tanja Schirmeister
- Kristina Endres
- Bernd Bufe
- Alexey Tarasov
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/37952320
- DOI
- 10.1016/j.bios.2023.115788
- eISSN
- 1873-4235
- Zeitschrift
- Biosens Bioelectron
- Schlüsselwörter
- Biosensors
- Electrochemical biosensors
- Optical biosensors
- Peptides
- Proteases
- Transducers
- Humans
- Peptide Hydrolases
- Biosensing Techniques
- Nanostructures
- Endopeptidases
- Biomarkers
- Electrochemical Techniques
- Sprache
- eng
- Country
- England
- Paginierung
- 115788
- PII
- S0956-5663(23)00730-3
- Datum der Veröffentlichung
- 2024
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2023
- Titel
- Protease detection in the biosensor era: A review.
- Sub types
- Journal Article
- Review
- Ausgabe der Zeitschrift
- 244
Datenquelle: PubMed
- Beziehungen:
- Eigentum von