Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • P Kehayias
  • A Jarmola
  • N Mosavian
  • I Fescenko
  • FM Benito
  • A Laraoui
  • J Smits
  • L Bougas
  • D Budker
  • A Neumann
  • SRJ Brueck
  • VM Acosta
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000406947700006&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1038/s41467-017-00266-4
Externe Identifier
  • Clarivate Analytics Document Solution ID: FC6JZ
  • PubMed Identifier: 28775280
ISSN
2041-1723
Zeitschrift
NATURE COMMUNICATIONS
Artikelnummer
ARTN 188
Datum der Veröffentlichung
2017
Status
Published
Titel
Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip
Sub types
  • Article
Ausgabe der Zeitschrift
8

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Abstract
<jats:title>Abstract</jats:title><jats:p>Sensors using nitrogen-vacancy centers in diamond are a promising tool for small-volume nuclear magnetic resonance (NMR) spectroscopy, but the limited sensitivity remains a challenge. Here we show nearly two orders of magnitude improvement in concentration sensitivity over previous nitrogen-vacancy and picoliter NMR studies. We demonstrate NMR spectroscopy of picoliter-volume solutions using a nanostructured diamond chip with dense, high-aspect-ratio nanogratings, enhancing the surface area by 15 times. The nanograting sidewalls are doped with nitrogen-vacancies located a few nanometers from the diamond surface to detect the NMR spectrum of roughly 1 pl of fluid lying within adjacent nanograting grooves. We perform <jats:sup>1</jats:sup>H and <jats:sup>19</jats:sup>F nuclear magnetic resonance spectroscopy at room temperature in magnetic fields below 50 mT. Using a solution of CsF in glycerol, we determine that 4 ± 2 × 10<jats:sup>12 19</jats:sup>F spins in a 1 pl volume can be detected with a signal-to-noise ratio of 3 in 1 s of integration.</jats:p>
Autoren
  • P Kehayias
  • A Jarmola
  • N Mosavian
  • I Fescenko
  • FM Benito
  • A Laraoui
  • J Smits
  • L Bougas
  • D Budker
  • A Neumann
  • SRJ Brueck
  • VM Acosta
DOI
10.1038/s41467-017-00266-4
eISSN
2041-1723
Ausgabe der Veröffentlichung
1
Zeitschrift
Nature Communications
Sprache
en
Artikelnummer
188
Online publication date
2017
Status
Published online
Herausgeber
Springer Science and Business Media LLC
Herausgeber URL
http://dx.doi.org/10.1038/s41467-017-00266-4
Datum der Datenerfassung
2022
Titel
Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip
Ausgabe der Zeitschrift
8

Datenquelle: Crossref

Abstract
Sensors using nitrogen-vacancy centers in diamond are a promising tool for small-volume nuclear magnetic resonance (NMR) spectroscopy, but the limited sensitivity remains a challenge. Here we show nearly two orders of magnitude improvement in concentration sensitivity over previous nitrogen-vacancy and picoliter NMR studies. We demonstrate NMR spectroscopy of picoliter-volume solutions using a nanostructured diamond chip with dense, high-aspect-ratio nanogratings, enhancing the surface area by 15 times. The nanograting sidewalls are doped with nitrogen-vacancies located a few nanometers from the diamond surface to detect the NMR spectrum of roughly 1 pl of fluid lying within adjacent nanograting grooves. We perform <sup>1</sup>H and <sup>19</sup>F nuclear magnetic resonance spectroscopy at room temperature in magnetic fields below 50 mT. Using a solution of CsF in glycerol, we determine that 4 ± 2 × 10<sup>12 19</sup>F spins in a 1 pl volume can be detected with a signal-to-noise ratio of 3 in 1 s of integration.Nitrogen vacancy (NV) centres in diamond can be used for NMR spectroscopy, but increased sensitivity is needed to avoid long measurement times. Kehayias et al. present a nanostructured diamond grating with a high density of NV centres, enabling NMR spectroscopy of picoliter-volume solutions.
Addresses
  • Department of Physics, Harvard University, Cambridge, 02138, MA, USA.
Autoren
  • P Kehayias
  • A Jarmola
  • N Mosavian
  • I Fescenko
  • FM Benito
  • A Laraoui
  • J Smits
  • L Bougas
  • D Budker
  • A Neumann
  • SRJ Brueck
  • VM Acosta
DOI
10.1038/s41467-017-00266-4
eISSN
2041-1723
Externe Identifier
  • PubMed Identifier: 28775280
  • PubMed Central ID: PMC5543112
Funding acknowledgements
  • NIGMS NIH HHS: R41 GM119925
Open access
true
ISSN
2041-1723
Ausgabe der Veröffentlichung
1
Zeitschrift
Nature communications
Schlüsselwörter
  • Diamond
  • Magnetic Resonance Spectroscopy
  • Nanostructures
Sprache
eng
Medium
Electronic
Online publication date
2017
Open access status
Open Access
Paginierung
188
Datum der Veröffentlichung
2017
Status
Published
Publisher licence
CC BY
Datum der Datenerfassung
2017
Titel
Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip.
Sub types
  • Research Support, Non-U.S. Gov't
  • research-article
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Journal Article
  • Research Support, N.I.H., Extramural
Ausgabe der Zeitschrift
8

Files

https://www.nature.com/articles/s41467-017-00266-4.pdf https://europepmc.org/articles/PMC5543112?pdf=render

Datenquelle: Europe PubMed Central

Abstract
Sensors using nitrogen-vacancy centers in diamond are a promising tool for small-volume nuclear magnetic resonance (NMR) spectroscopy, but the limited sensitivity remains a challenge. Here we show nearly two orders of magnitude improvement in concentration sensitivity over previous nitrogen-vacancy and picoliter NMR studies. We demonstrate NMR spectroscopy of picoliter-volume solutions using a nanostructured diamond chip with dense, high-aspect-ratio nanogratings, enhancing the surface area by 15 times. The nanograting sidewalls are doped with nitrogen-vacancies located a few nanometers from the diamond surface to detect the NMR spectrum of roughly 1 pl of fluid lying within adjacent nanograting grooves. We perform 1H and 19F nuclear magnetic resonance spectroscopy at room temperature in magnetic fields below 50 mT. Using a solution of CsF in glycerol, we determine that 4 ± 2 × 1012 19F spins in a 1 pl volume can be detected with a signal-to-noise ratio of 3 in 1 s of integration.Nitrogen vacancy (NV) centres in diamond can be used for NMR spectroscopy, but increased sensitivity is needed to avoid long measurement times. Kehayias et al. present a nanostructured diamond grating with a high density of NV centres, enabling NMR spectroscopy of picoliter-volume solutions.
Date of acceptance
2017
Autoren
  • P Kehayias
  • A Jarmola
  • N Mosavian
  • I Fescenko
  • FM Benito
  • A Laraoui
  • J Smits
  • L Bougas
  • D Budker
  • A Neumann
  • SRJ Brueck
  • VM Acosta
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/28775280
DOI
10.1038/s41467-017-00266-4
eISSN
2041-1723
Externe Identifier
  • PubMed Central ID: PMC5543112
Funding acknowledgements
  • NIGMS NIH HHS: R41 GM119925
Ausgabe der Veröffentlichung
1
Zeitschrift
Nat Commun
Schlüsselwörter
  • Diamond
  • Magnetic Resonance Spectroscopy
  • Nanostructures
Sprache
eng
Country
England
Paginierung
188
PII
10.1038/s41467-017-00266-4
Datum der Veröffentlichung
2017
Status
Published online
Datum, an dem der Datensatz öffentlich gemacht wurde
2018
Titel
Solution nuclear magnetic resonance spectroscopy on a nanostructured diamond chip.
Sub types
  • Journal Article
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
Ausgabe der Zeitschrift
8

Datenquelle: PubMed

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