The influence of parasite load on transcriptional activity and morphology of a cestode and its ant intermediate host
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Tom Sistermans
- Juliane Hartke
- Marah Stoldt
- Romain Libbrecht
- Susanne Foitzik
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000994141500001&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1111/mec.16995
- eISSN
- 1365-294X
- Externe Identifier
- Clarivate Analytics Document Solution ID: M6YV4
- PubMed Identifier: 37222006
- ISSN
- 0962-1083
- Ausgabe der Veröffentlichung
- 15
- Zeitschrift
- MOLECULAR ECOLOGY
- Schlüsselwörter
- cestode
- host-parasite interaction
- manipulation
- parasite burden
- parasite escape
- Paginierung
- 4412 - 4426
- Datum der Veröffentlichung
- 2023
- Status
- Published
- Titel
- The influence of parasite load on transcriptional activity and morphology of a cestode and its ant intermediate host
- Sub types
- Article
- Ausgabe der Zeitschrift
- 32
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:p>Parasites with complex life cycles are known to induce phenotypic changes in their intermediate hosts to increase transmission to the final host. The magnitude of these changes could increase with the number of parasites, which would be beneficial to co‐infecting parasites. Yet, adverse effects of high parasite load (i.e. many parasites in a single host) might stress both hosts and parasites (e.g. through an increased immune response). We investigated the consequences of parasite load on the transcriptional activity and morphology of the cestode<jats:italic>Anomotaenia brevis</jats:italic>and its intermediate host, the ant<jats:italic>Temnothorax nylanderi</jats:italic>. We demonstrated that many differentially expressed host genes shifted with parasite load, and their functions indicate a stronger immune response and fight against oxidative stress in heavily infected hosts. The expression of other host genes responded to infection in an all‐or‐nothing manner, as did the morphology of the host workers. However, the cestodes became smaller when they competed with other parasites for resources from a single host. Their expression profile further indicated shifts in host immune avoidance, starvation resistance and vesicle‐mediated transport. In summary, our study reveals clear consequences of parasite load and highlights specific processes and traits affected by this.</jats:p>
- Autoren
- Tom Sistermans
- Juliane Hartke
- Marah Stoldt
- Romain Libbrecht
- Susanne Foitzik
- DOI
- 10.1111/mec.16995
- eISSN
- 1365-294X
- ISSN
- 0962-1083
- Ausgabe der Veröffentlichung
- 15
- Zeitschrift
- Molecular Ecology
- Sprache
- en
- Online publication date
- 2023
- Paginierung
- 4412 - 4426
- Datum der Veröffentlichung
- 2023
- Status
- Published
- Herausgeber
- Wiley
- Herausgeber URL
- http://dx.doi.org/10.1111/mec.16995
- Datum der Datenerfassung
- 2023
- Titel
- The influence of parasite load on transcriptional activity and morphology of a cestode and its ant intermediate host
- Ausgabe der Zeitschrift
- 32
Datenquelle: Crossref
- Abstract
- Parasites with complex life cycles are known to induce phenotypic changes in their intermediate hosts to increase transmission to the final host. The magnitude of these changes could increase with the number of parasites, which would be beneficial to co-infecting parasites. Yet, adverse effects of high parasite load (i.e. many parasites in a single host) might stress both hosts and parasites (e.g. through an increased immune response). We investigated the consequences of parasite load on the transcriptional activity and morphology of the cestode Anomotaenia brevis and its intermediate host, the ant Temnothorax nylanderi. We demonstrated that many differentially expressed host genes shifted with parasite load, and their functions indicate a stronger immune response and fight against oxidative stress in heavily infected hosts. The expression of other host genes responded to infection in an all-or-nothing manner, as did the morphology of the host workers. However, the cestodes became smaller when they competed with other parasites for resources from a single host. Their expression profile further indicated shifts in host immune avoidance, starvation resistance and vesicle-mediated transport. In summary, our study reveals clear consequences of parasite load and highlights specific processes and traits affected by this.
- Addresses
- Institute of Organismic and Molecular Evolution, Johannes Gutenberg University Mainz, Mainz, Germany.
- Autoren
- Tom Sistermans
- Juliane Hartke
- Marah Stoldt
- Romain Libbrecht
- Susanne Foitzik
- DOI
- 10.1111/mec.16995
- eISSN
- 1365-294X
- Externe Identifier
- PubMed Identifier: 37222006
- Funding acknowledgements
- Deutsche Forschungsgemeinschaft: GRK2526/1
- Open access
- false
- ISSN
- 0962-1083
- Ausgabe der Veröffentlichung
- 15
- Zeitschrift
- Molecular ecology
- Schlüsselwörter
- Animals
- Ants
- Cestoda
- Parasites
- Host-Parasite Interactions
- Parasite Load
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2023
- Paginierung
- 4412 - 4426
- Datum der Veröffentlichung
- 2023
- Status
- Published
- Publisher licence
- CC BY-NC-ND
- Datum der Datenerfassung
- 2023
- Titel
- The influence of parasite load on transcriptional activity and morphology of a cestode and its ant intermediate host.
- Sub types
- Research Support, Non-U.S. Gov't
- Journal Article
- Ausgabe der Zeitschrift
- 32
Datenquelle: Europe PubMed Central
- Abstract
- Parasites with complex life cycles are known to induce phenotypic changes in their intermediate hosts to increase transmission to the final host. The magnitude of these changes could increase with the number of parasites, which would be beneficial to co-infecting parasites. Yet, adverse effects of high parasite load (i.e. many parasites in a single host) might stress both hosts and parasites (e.g. through an increased immune response). We investigated the consequences of parasite load on the transcriptional activity and morphology of the cestode Anomotaenia brevis and its intermediate host, the ant Temnothorax nylanderi. We demonstrated that many differentially expressed host genes shifted with parasite load, and their functions indicate a stronger immune response and fight against oxidative stress in heavily infected hosts. The expression of other host genes responded to infection in an all-or-nothing manner, as did the morphology of the host workers. However, the cestodes became smaller when they competed with other parasites for resources from a single host. Their expression profile further indicated shifts in host immune avoidance, starvation resistance and vesicle-mediated transport. In summary, our study reveals clear consequences of parasite load and highlights specific processes and traits affected by this.
- Date of acceptance
- 2023
- Autoren
- Tom Sistermans
- Juliane Hartke
- Marah Stoldt
- Romain Libbrecht
- Susanne Foitzik
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/37222006
- DOI
- 10.1111/mec.16995
- eISSN
- 1365-294X
- Ausgabe der Veröffentlichung
- 15
- Zeitschrift
- Mol Ecol
- Schlüsselwörter
- cestode
- host-parasite interaction
- manipulation
- parasite burden
- parasite escape
- Animals
- Ants
- Host-Parasite Interactions
- Cestoda
- Parasites
- Parasite Load
- Sprache
- eng
- Country
- England
- Paginierung
- 4412 - 4426
- Datum der Veröffentlichung
- 2023
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2023
- Titel
- The influence of parasite load on transcriptional activity and morphology of a cestode and its ant intermediate host.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 32
Datenquelle: PubMed
- Author's licence
- CC-BY-NC-ND
- Autoren
- Tom Sistermans
- Juliane Hartke
- Marah Stoldt
- Romain Libbrecht
- Susanne Foitzik
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- DFG-491381577-H
- Resource version
- Published version
- DOI
- 10.1111/mec.16995
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 1365-294X
- Ausgabe der Veröffentlichung
- 15
- Zeitschrift
- Molecular ecology
- Schlüsselwörter
- 570 Biowissenschaften
- 570 Life sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 4412 - 4426
- Datum der Veröffentlichung
- 2023
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/9544
- Herausgeber
- Wiley-Blackwell
- Datum der Datenerfassung
- 2023
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2023
- Zugang
- Public
- Titel
- The influence of parasite load on transcriptional activity and morphology of a cestode and its ant intermediate host
- Ausgabe der Zeitschrift
- 32
Files
the_influence_of_parasite_loa-20230901153853257.pdf
Datenquelle: OPENSCIENCE.UB