Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations over Evolutionary Timescales

Autoren

Talia L Karasov
Juliana Almario
Claudia Friedemann
Wei Ding
Michael Giolai
Darren Heavens
Sonja Kersten
Derek S Lundberg
Manuela Neumann
Julian Regalado
Richard A Neher
Eric Kemen
Detlef Weigel

DOI

10.1016/j.chom.2018.06.011

ISSN

1931-3128

Ausgabe der Veröffentlichung

1

Zeitschrift

Cell Host & Microbe

Sprache

en

Paginierung

168 - 179.e4

Datum der Veröffentlichung

2018

Status

Published

Herausgeber

Elsevier BV

Herausgeber URL

http://dx.doi.org/10.1016/j.chom.2018.06.011

Datum der Datenerfassung

2020

Titel

Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations over Evolutionary Timescales

Ausgabe der Zeitschrift

24

Datenquelle: Crossref

Abstract

Crop disease outbreaks are often associated with clonal expansions of single pathogenic lineages. To determine whether similar boom-and-bust scenarios hold for wild pathosystems, we carried out a multi-year, multi-site survey of Pseudomonas in its natural host Arabidopsis thaliana. The most common Pseudomonas lineage corresponded to a ubiquitous pathogenic clade. Sequencing of 1,524 genomes revealed this lineage to have diversified approximately 300,000 years ago, containing dozens of genetically identifiable pathogenic sublineages. There is differentiation at the level of both gene content and disease phenotype, although the differentiation may not provide fitness advantages to specific sublineages. The coexistence of sublineages indicates that in contrast to crop systems, no single strain has been able to overtake the studied A. thaliana populations in the recent past. Our results suggest that selective pressures acting on a plant pathogen in wild hosts are likely to be much more complex than those in agricultural systems.

Addresses

Department of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.

Autoren

Talia L Karasov
Juliana Almario
Claudia Friedemann
Wei Ding
Michael Giolai
Darren Heavens
Sonja Kersten
Derek S Lundberg
Manuela Neumann
Julian Regalado
Richard A Neher
Eric Kemen
Detlef Weigel

DOI

10.1016/j.chom.2018.06.011

eISSN

1934-6069

Externe Identifier

PubMed Identifier: 30001519
PubMed Central ID: PMC6054916

Funding acknowledgements

Max Planck Society:
HFSP: LT000348/2016-L
EMBO: 1483-2015
HFSP: LT000565/2015-L
European Research Council:
Earlham Institute (Funder): EI-G-RL

Open access

true

ISSN

1931-3128

Ausgabe der Veröffentlichung

1

Zeitschrift

Cell host & microbe

Schlüsselwörter

Pseudomonas
Arabidopsis
Plant Leaves
Crops, Agricultural
Pseudomonas Infections
DNA, Bacterial
RNA, Ribosomal, 16S
Phylogeny
Plant Diseases
Metagenome
Biological Evolution
Whole Genome Sequencing

Sprache

eng

Medium

Print

Open access status

Open Access

Paginierung

168 - 179.e4

Datum der Veröffentlichung

2018

Status

Published

Publisher licence

CC BY

Datum der Datenerfassung

2018

Titel

Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations over Evolutionary Timescales.

Sub types

Research Support, Non-U.S. Gov't
research-article
Journal Article

Ausgabe der Zeitschrift

24

Datenquelle: Europe PubMed Central

Abstract

Crop disease outbreaks are often associated with clonal expansions of single pathogenic lineages. To determine whether similar boom-and-bust scenarios hold for wild pathosystems, we carried out a multi-year, multi-site survey of Pseudomonas in its natural host Arabidopsis thaliana. The most common Pseudomonas lineage corresponded to a ubiquitous pathogenic clade. Sequencing of 1,524 genomes revealed this lineage to have diversified approximately 300,000 years ago, containing dozens of genetically identifiable pathogenic sublineages. There is differentiation at the level of both gene content and disease phenotype, although the differentiation may not provide fitness advantages to specific sublineages. The coexistence of sublineages indicates that in contrast to crop systems, no single strain has been able to overtake the studied A. thaliana populations in the recent past. Our results suggest that selective pressures acting on a plant pathogen in wild hosts are likely to be much more complex than those in agricultural systems.

Date of acceptance

2018

Autoren

Talia L Karasov
Juliana Almario
Claudia Friedemann
Wei Ding
Michael Giolai
Darren Heavens
Sonja Kersten
Derek S Lundberg
Manuela Neumann
Julian Regalado
Richard A Neher
Eric Kemen
Detlef Weigel

Autoren-URL

https://www.ncbi.nlm.nih.gov/pubmed/30001519

DOI

10.1016/j.chom.2018.06.011

eISSN

1934-6069

Externe Identifier

PubMed Central ID: PMC6054916

Funding acknowledgements

European Research Council:

Ausgabe der Veröffentlichung

1

Zeitschrift

Cell Host Microbe

Schlüsselwörter

A. thaliana
clonal expansion
microbial population genomics
pathogenicity
pseudomonas
Arabidopsis
Biological Evolution
Crops, Agricultural
DNA, Bacterial
Metagenome
Phylogeny
Plant Diseases
Plant Leaves
Pseudomonas
Pseudomonas Infections
RNA, Ribosomal, 16S
Whole Genome Sequencing

Sprache

eng

Country

United States

Paginierung

168 - 179.e4

PII

S1931-3128(18)30323-8

Datum der Veröffentlichung

2018

Status

Published

Datum, an dem der Datensatz öffentlich gemacht wurde

2019

Titel

Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations over Evolutionary Timescales.

Sub types

Journal Article
Research Support, Non-U.S. Gov't

Ausgabe der Zeitschrift

24

Datenquelle: PubMed

Arabidopsis thaliana and Pseudomonas Pathogens Exhibit Stable Associations over Evolutionary Timescales

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