Depressive symptoms predict the incidence of common chronic diseases in women and men in a representative community sample

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Abstract
<jats:title>Abstract</jats:title><jats:sec id="S0033291722000861_sec_a1"><jats:title>Background</jats:title><jats:p>Depression, the most frequent and harmful mental disorder, has been associated with specific somatic diseases as the leading cause of death. The purposes of this prospective study were to predict incident chronic diseases based on baseline depressive symptoms and to test sex-dependent effects.</jats:p></jats:sec><jats:sec id="S0033291722000861_sec_a2" sec-type="methods"><jats:title>Methods</jats:title><jats:p>In a representative German community sample of over 12 000 participants, baseline depressive symptoms (assessed using the Patient Health Questionnaire-9) were tested as a predictor of new onset of cardiovascular disease (CVD), chronic obstructive lung disease, diabetes, cancer, and migraine at 5-year follow-up. To study disease incidence, we created subsamples for each chronic disease by excluding participants who already had the respective disease at baseline. Potential confounders were included in logistic regression models and sex-specific analyses were performed.</jats:p></jats:sec><jats:sec id="S0033291722000861_sec_a3" sec-type="results"><jats:title>Results</jats:title><jats:p>Controlling for demographic characteristics and loneliness, in men and women, baseline depressive symptoms were predictive of CVD, chronic obstructive lung disease, diabetes, and migraine, but not of cancer. When we additionally adjusted for metabolic and lifestyle risk factors, there was an 8% increase of chronic obstructive lung disease and migraine per point of depressive symptoms. There was a trend for CVD (4%; <jats:italic>p</jats:italic> = 0.053). Sex-sensitive analyses revealed trends for the relevance of depressive symptoms for CVD in men (<jats:italic>p</jats:italic> = 0.065), and for diabetes in women (<jats:italic>p</jats:italic> = 0.077).</jats:p></jats:sec><jats:sec id="S0033291722000861_sec_a4" sec-type="conclusions"><jats:title>Conclusions</jats:title><jats:p>These findings underscore the need to implement screening for depression in the treatment of major somatic illnesses. At the same time, depressed patients should be screened for metabolic and lifestyle risk factors and for somatic diseases and offered lifestyle interventions.</jats:p></jats:sec>
Autoren
  • Daniëlle Otten
  • Mareike Ernst
  • Antonia M Werner
  • Ana N Tibubos
  • Iris Reiner
  • Elmar Brähler
  • Jörg Wiltink
  • Matthias Michal
  • Markus Nagler
  • Philipp S Wild
  • Thomas Münzel
  • Jochem König
  • Karl J Lackner
  • Norbert Peiffer
  • Manfred E Beutel
DOI
10.1017/s0033291722000861
eISSN
1469-8978
ISSN
0033-2917
Ausgabe der Veröffentlichung
9
Zeitschrift
Psychological Medicine
Sprache
en
Online publication date
2022
Paginierung
4172 - 4180
Datum der Veröffentlichung
2023
Status
Published
Herausgeber
Cambridge University Press (CUP)
Herausgeber URL
http://dx.doi.org/10.1017/s0033291722000861
Datum der Datenerfassung
2023
Titel
Depressive symptoms predict the incidence of common chronic diseases in women and men in a representative community sample
Ausgabe der Zeitschrift
53

Datenquelle: Crossref

Andere Metadatenquellen:
Author's licence
CC-BY
Autoren
  • Daniëlle Otten
  • Mareike Ernst
  • Antonia M Werner
  • Ana N Tibubos
  • Iris Reiner
  • Elmar Brähler
  • Jörg Wiltink
  • Matthias Michal
  • Markus Nagler
  • Philipp S Wild
  • Thomas Münzel
  • Jochem König
  • Karl J Lackner
  • Norbert Peiffer
  • Manfred E Beutel
Hosting institution
Universitätsbibliothek Mainz
Sammlungen
  • DFG-491381577-H
Resource version
Published version
DOI
10.1017/S0033291722000861
File(s) embargoed
false
Open access
true
ISSN
1469-8978
Zeitschrift
Psychological Medicine
Schlüsselwörter
  • 610 Medizin
  • 610 Medical sciences
Sprache
eng
Open access status
Open Access
Datum der Veröffentlichung
2022
Public URL
https://openscience.ub.uni-mainz.de/handle/20.500.12030/8844
Herausgeber
Cambridge University Press
Datum der Datenerfassung
2023
Datum, an dem der Datensatz öffentlich gemacht wurde
2023
Zugang
Public
Titel
Depressive symptoms predict the incidence of common chronic diseases in women and men in a representative community sample
Ausgabe der Zeitschrift
Version of Record (VoR)

Files

depressive_symptoms_predict_t-20230221134423181.pdf

Datenquelle: OPENSCIENCE.UB

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