Rabifier2: an improved bioinformatic classifier of Rab GTPases

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000397264100020&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1093/bioinformatics/btw654
eISSN
1367-4811
Externe Identifier
  • Clarivate Analytics Document Solution ID: EP3DY
  • PubMed Identifier: 27797763
ISSN
1367-4803
Ausgabe der Veröffentlichung
4
Zeitschrift
BIOINFORMATICS
Paginierung
568 - 570
Datum der Veröffentlichung
2017
Status
Published
Titel
Rabifier2: an improved bioinformatic classifier of Rab GTPases
Sub types
  • Article
Ausgabe der Zeitschrift
33

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Abstract
<jats:title>Abstract</jats:title> <jats:sec> <jats:title>Summary</jats:title> <jats:p>The Rab family of small GTPases regulates and provides specificity to the endomembrane trafficking system; each Rab subfamily is associated with specific pathways. Thus, characterization of Rab repertoires provides functional information about organisms and evolution of the eukaryotic cell. Yet, the complex structure of the Rab family limits the application of existing methods for protein classification. Here, we present a major redesign of the Rabifier, a bioinformatic pipeline for detection and classification of Rab GTPases. It is more accurate, significantly faster than the original version and is now open source, both the code and the data, allowing for community participation.</jats:p> </jats:sec> <jats:sec> <jats:title>Availability and Implementation</jats:title> <jats:p>Rabifier and RabDB are freely available through the web at http://rabdb.org. The Rabifier package can be downloaded from the Python Package Index at https://pypi.python.org/pypi/rabifier, the source code is available at Github https://github.com/evocell/rabifier.</jats:p> </jats:sec> <jats:sec> <jats:title>Supplementary information</jats:title> <jats:p>Supplementary data are available at Bioinformatics online.</jats:p> </jats:sec>
Autoren
DOI
10.1093/bioinformatics/btw654
eISSN
1367-4811
ISSN
1367-4803
Ausgabe der Veröffentlichung
4
Zeitschrift
Bioinformatics
Sprache
en
Online publication date
2016
Paginierung
568 - 570
Datum der Veröffentlichung
2017
Status
Published
Herausgeber
Oxford University Press (OUP)
Herausgeber URL
http://dx.doi.org/10.1093/bioinformatics/btw654
Datum der Datenerfassung
2023
Titel
Rabifier2: an improved bioinformatic classifier of Rab GTPases
Ausgabe der Zeitschrift
33

Datenquelle: Crossref

Abstract
<h4>Summary</h4>The Rab family of small GTPases regulates and provides specificity to the endomembrane trafficking system; each Rab subfamily is associated with specific pathways. Thus, characterization of Rab repertoires provides functional information about organisms and evolution of the eukaryotic cell. Yet, the complex structure of the Rab family limits the application of existing methods for protein classification. Here, we present a major redesign of the Rabifier, a bioinformatic pipeline for detection and classification of Rab GTPases. It is more accurate, significantly faster than the original version and is now open source, both the code and the data, allowing for community participation.<h4>Availability and implementation</h4>Rabifier and RabDB are freely available through the web at http://rabdb.org . The Rabifier package can be downloaded from the Python Package Index at https://pypi.python.org/pypi/rabifier , the source code is available at Github https://github.com/evocell/rabifier .<h4>Contact</h4>jsurkont@igc.gulbenkian.pt or jleal@igc.gulbenkian.pt.<h4>Supplementary information</h4>Supplementary data are available at Bioinformatics online.
Addresses
  • Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
Autoren
DOI
10.1093/bioinformatics/btw654
eISSN
1367-4811
Externe Identifier
  • PubMed Identifier: 27797763
Funding acknowledgements
  • Fundação para a Ciência e a Tecnologia: PTDC/EBB-BIO/119006/2010
  • Fundação para a Ciência e a Tecnologia: SFRH/BD/51880/2012
Open access
false
ISSN
1367-4803
Ausgabe der Veröffentlichung
4
Zeitschrift
Bioinformatics (Oxford, England)
Schlüsselwörter
  • Animals
  • Humans
  • rab GTP-Binding Proteins
  • Computational Biology
  • Software
  • Eukaryota
Sprache
eng
Medium
Print
Paginierung
568 - 570
Datum der Veröffentlichung
2017
Status
Published
Datum der Datenerfassung
2016
Titel
Rabifier2: an improved bioinformatic classifier of Rab GTPases.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
33

Datenquelle: Europe PubMed Central

Abstract
SUMMARY: The Rab family of small GTPases regulates and provides specificity to the endomembrane trafficking system; each Rab subfamily is associated with specific pathways. Thus, characterization of Rab repertoires provides functional information about organisms and evolution of the eukaryotic cell. Yet, the complex structure of the Rab family limits the application of existing methods for protein classification. Here, we present a major redesign of the Rabifier, a bioinformatic pipeline for detection and classification of Rab GTPases. It is more accurate, significantly faster than the original version and is now open source, both the code and the data, allowing for community participation. AVAILABILITY AND IMPLEMENTATION: Rabifier and RabDB are freely available through the web at http://rabdb.org . The Rabifier package can be downloaded from the Python Package Index at https://pypi.python.org/pypi/rabifier , the source code is available at Github https://github.com/evocell/rabifier . CONTACT: jsurkont@igc.gulbenkian.pt or jleal@igc.gulbenkian.pt. SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Date of acceptance
2016
Autoren
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/27797763
DOI
10.1093/bioinformatics/btw654
eISSN
1367-4811
Ausgabe der Veröffentlichung
4
Zeitschrift
Bioinformatics
Schlüsselwörter
  • Animals
  • Computational Biology
  • Eukaryota
  • Humans
  • Software
  • rab GTP-Binding Proteins
Sprache
eng
Country
England
Paginierung
568 - 570
PII
btw654
Datum der Veröffentlichung
2017
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2017
Titel
Rabifier2: an improved bioinformatic classifier of Rab GTPases.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
33

Datenquelle: PubMed

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