Anterior Chamber Angle in Adults Born Extremely, Very, and Moderately Preterm with and without Retinopathy of Prematurity—Results of the Gutenberg Prematurity Eye Study

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Abstract
<jats:p>Purpose: To determine whether prematurity and associated factors affect the anterior chamber angle (ACA) width in adulthood. Methods: The Gutenberg Prematurity Eye Study (GPES) is a retrospective cohort study with a prospective ophthalmologic examination of adults (age 18–52 years) in Germany. All participants were examined with Scheimpflug imaging (Pentacam HR, Oculus Optikgeräte GmbH, Wetzlar, Germany) using linear regression analysis to assess the associations of ACA in the different sectors with gestational age (GA), birth weight, birth weight percentile, retinopathy of prematurity (ROP), ROP treatment, placental insufficiency, preeclampsia, and breastfeeding. Results: In total, 516 eyes of 319 preterm and full-term individuals (aged 28.9 ± 8.8 years, 188 females) were examined. ROP treatment was associated with smaller ACA width in the nasal (B = −9.6 [95%CI: −14.7; −4.5] degree; p &lt; 0.001) and temporal positions (B = −11.5 [95%CI: −17.7; −5.3] degree; p = 0.001), whereas non-treated individuals with ROP had an unaltered ACA width, as did individuals with low gestational age without ROP. Conclusion: Advanced stages of ROP following treatment with laser- and cryocoagulation lead to a smaller ACA width until adulthood, and hence may increase the risk of angle closure in later life.</jats:p>
Autoren
  • Achim Fieß
  • Sandra Gißler
  • Eva Mildenberger
  • Michael S Urschitz
  • Agnes Fauer
  • Heike M Elflein
  • Fred Zepp
  • Bernhard Stoffelns
  • Norbert Pfeiffer
  • Alexander K Schuster
DOI
10.3390/children9020281
eISSN
2227-9067
Ausgabe der Veröffentlichung
2
Zeitschrift
Children
Sprache
en
Online publication date
2022
Paginierung
281 - 281
Status
Published online
Herausgeber
MDPI AG
Herausgeber URL
http://dx.doi.org/10.3390/children9020281
Datum der Datenerfassung
2022
Titel
Anterior Chamber Angle in Adults Born Extremely, Very, and Moderately Preterm with and without Retinopathy of Prematurity—Results of the Gutenberg Prematurity Eye Study
Ausgabe der Zeitschrift
9

Datenquelle: Crossref

Andere Metadatenquellen:
Author's licence
CC-BY
Autoren
  • Achim Fieß
  • Sandra Gißler
  • Eva Mildenberger
  • Michael S Urschitz
  • Agnes Fauer
  • Heike M Elflein
  • Fred Zepp
  • Bernhard Stoffelns
  • Norbert Pfeiffer
  • Alexander K Schuster
Hosting institution
Universitätsbibliothek Mainz
Sammlungen
  • DFG-491381577-G
Resource version
Published version
DOI
10.3390/children9020281
Funding acknowledgements
  • Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 491381577
File(s) embargoed
false
Open access
true
ISSN
2227-9067
Ausgabe der Veröffentlichung
2
Zeitschrift
Children
Schlüsselwörter
  • 610 Medizin
  • 610 Medical sciences
Sprache
eng
Open access status
Open Access
Paginierung
281
Datum der Veröffentlichung
2022
Public URL
https://openscience.ub.uni-mainz.de/handle/20.500.12030/8684
Herausgeber
MDPI
Datum der Datenerfassung
2023
Datum, an dem der Datensatz öffentlich gemacht wurde
2023
Zugang
Public
Titel
Anterior chamber angle in adults born extremely, very, and moderately preterm with and without retinopathy of prematurity : results of the Gutenberg Prematurity Eye Study
Ausgabe der Zeitschrift
9

Files

anterior_chamber_angle_in_adu-20230126113423581.pdf

Datenquelle: OPENSCIENCE.UB

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