Response and adaptation of skeletal muscle to exercise - the role of reactive oxygen species
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Andreas Michael Niess
- Perikles Simon
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000253943900005&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.2741/2431
- eISSN
- 1093-4715
- Externe Identifier
- Clarivate Analytics Document Solution ID: 273PJ
- PubMed Identifier: 17569613
- ISSN
- 1093-9946
- Zeitschrift
- FRONTIERS IN BIOSCIENCE-LANDMARK
- Schlüsselwörter
- skeletal muscle
- exercise
- training
- reactive oxygen species
- ros
- oxidative stress
- redox-regulation
- adaptation
- review
- Paginierung
- 4826 - 4838
- Datum der Veröffentlichung
- 2007
- Status
- Published
- Titel
- Response and adaptation of skeletal muscle to exercise - the role of reactive oxygen species
- Sub types
- Review
- Ausgabe der Zeitschrift
- 12
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Andreas Michael Niess
- DOI
- 10.2741/2431
- eISSN
- 1093-4715
- ISSN
- 1093-9946
- Ausgabe der Veröffentlichung
- 12
- Zeitschrift
- Frontiers in Bioscience
- Sprache
- en
- Paginierung
- 4826 - 4826
- Datum der Veröffentlichung
- 2007
- Status
- Published
- Herausgeber
- IMR Press
- Herausgeber URL
- http://dx.doi.org/10.2741/2431
- Datum der Datenerfassung
- 2022
- Titel
- Response and adaptation of skeletal muscle to exercise - the role of reactive oxygen species
- Ausgabe der Zeitschrift
- 12
Datenquelle: Crossref
- Abstract
- In the last 30 years, the role of reactive oxygen species (ROS) in exercise physiology has received considerable attention. Acute physical exertion has been shown to induce an augmented generation of ROS in skeletal muscle via different mechanisms. There is evidence that ROS formation in response to vigorous physical exertion can result in oxidative stress. More recent research has revealed the important role of ROS as signaling molecules. ROS modulate contractile function in unfatigued and fatigued skeletal muscle. Furthermore, involvement of ROS in the modulation of gene expression via redox-sensitive transcription pathways represents an important regulatory mechanism, which has been suggested to be involved in the process of training adaptation. In this context, the adaptation of endogenous antioxidant systems in response to regular training reflects a potential mechanism responsible for augmented tolerance of skeletal muscle to exercise-induced stress. The present review outlines current knowledge and more recent findings in this area by focussing on major sources of ROS production, oxidative stress, tissue damage, contractile force, and redox-regulated gene expression in exercising skeletal muscle.
- Addresses
- Medical Clinic, Department of Sports Medicine, University of Tuebingen, Germany. andreas.niess@med.uni-tuebingen.de
- Autoren
- Andreas Michael Niess
- Perikles Simon
- DOI
- 10.2741/2431
- Externe Identifier
- PubMed Identifier: 17569613
- Open access
- false
- ISSN
- 1093-9946
- Zeitschrift
- Frontiers in bioscience : a journal and virtual library
- Schlüsselwörter
- Muscle, Skeletal
- Animals
- Humans
- DNA Damage
- Reactive Oxygen Species
- Antioxidants
- Exercise Test
- Exercise
- Adaptation, Physiological
- Signal Transduction
- Oxidation-Reduction
- Lipid Peroxidation
- Oxidative Stress
- Biomechanical Phenomena
- Sprache
- eng
- Medium
- Electronic
- Online publication date
- 2007
- Paginierung
- 4826 - 4838
- Datum der Veröffentlichung
- 2007
- Status
- Published
- Datum der Datenerfassung
- 2007
- Titel
- Response and adaptation of skeletal muscle to exercise--the role of reactive oxygen species.
- Sub types
- Review
- Journal Article
- Ausgabe der Zeitschrift
- 12
Datenquelle: Europe PubMed Central
- Abstract
- In the last 30 years, the role of reactive oxygen species (ROS) in exercise physiology has received considerable attention. Acute physical exertion has been shown to induce an augmented generation of ROS in skeletal muscle via different mechanisms. There is evidence that ROS formation in response to vigorous physical exertion can result in oxidative stress. More recent research has revealed the important role of ROS as signaling molecules. ROS modulate contractile function in unfatigued and fatigued skeletal muscle. Furthermore, involvement of ROS in the modulation of gene expression via redox-sensitive transcription pathways represents an important regulatory mechanism, which has been suggested to be involved in the process of training adaptation. In this context, the adaptation of endogenous antioxidant systems in response to regular training reflects a potential mechanism responsible for augmented tolerance of skeletal muscle to exercise-induced stress. The present review outlines current knowledge and more recent findings in this area by focussing on major sources of ROS production, oxidative stress, tissue damage, contractile force, and redox-regulated gene expression in exercising skeletal muscle.
- Autoren
- Andreas Michael Niess
- Perikles Simon
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/17569613
- DOI
- 10.2741/2431
- ISSN
- 1093-9946
- Zeitschrift
- Front Biosci
- Schlüsselwörter
- Adaptation, Physiological
- Animals
- Antioxidants
- Biomechanical Phenomena
- DNA Damage
- Exercise
- Exercise Test
- Humans
- Lipid Peroxidation
- Muscle, Skeletal
- Oxidation-Reduction
- Oxidative Stress
- Reactive Oxygen Species
- Signal Transduction
- Sprache
- eng
- Country
- United States
- Paginierung
- 4826 - 4838
- PII
- 2431
- Datum der Veröffentlichung
- 2007
- Status
- Published online
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2007
- Titel
- Response and adaptation of skeletal muscle to exercise--the role of reactive oxygen species.
- Sub types
- Journal Article
- Review
- Ausgabe der Zeitschrift
- 12
Datenquelle: PubMed
- Beziehungen:
- Eigentum von