Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Fabian Springer
  • Stefan Ehehalt
  • Julia Sommer
  • Verena Ballweg
  • Jurgen Machann
  • Gerhard Binder
  • Claus D Claussen
  • Fritz Schick
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000304590300022&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/j.ejrad.2011.04.006
eISSN
1872-7727
Externe Identifier
  • Clarivate Analytics Document Solution ID: 949QI
  • PubMed Identifier: 21543171
ISSN
0720-048X
Ausgabe der Veröffentlichung
7
Zeitschrift
EUROPEAN JOURNAL OF RADIOLOGY
Schlüsselwörter
  • Magnetic resonance imaging
  • Adipose tissue distribution
  • Overweight and obesity
  • Adolescents
  • Anthropometry
Paginierung
1488 - 1494
Datum der Veröffentlichung
2012
Status
Published
Titel
Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry
Sub types
  • Article
Ausgabe der Zeitschrift
81

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Autoren
  • Fabian Springer
  • Stefan Ehehalt
  • Julia Sommer
  • Verena Ballweg
  • Jürgen Machann
  • Gerhard Binder
  • Claus D Claussen
  • Fritz Schick
DOI
10.1016/j.ejrad.2011.04.006
ISSN
0720-048X
Ausgabe der Veröffentlichung
7
Zeitschrift
European Journal of Radiology
Sprache
en
Paginierung
1488 - 1494
Datum der Veröffentlichung
2012
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/j.ejrad.2011.04.006
Datum der Datenerfassung
2019
Titel
Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry
Ausgabe der Zeitschrift
81

Datenquelle: Crossref

Abstract
<h4>Objectives</h4>To evaluate 5-slice stack/single-slice MRI approaches and anthropometric measures as predictors for metabolically relevant whole-body adipose tissue (AT) compartments in overweight/obese adolescents.<h4>Methods</h4>Forty adolescents (22 males, age 11.4-16.1 years) were included with a BMI above the 90th percentile. Volumes of whole-body AT compartments, i.e. total AT (TAT), subcutaneous AT (SCAT) and visceral AT (VAT), were determined using a breath-hold T1-weighted-FSE-MR-sequence and semi-automated segmentation serving as the gold standard. SCAT, VAT and TAT was estimated by either axially oriented single-slices or 5-slice-stacks centred at specific anatomic landmarks (umbilicus, head of femur and humerus). Furthermore, anthropometric measures were also evaluated as predictors of whole-body AT compartments.<h4>Results</h4>Strong correlations were found for both genders between TAT/SCAT and single-slice evaluation (e.g. whole-body SCAT-SCAT at umbilicus level: r = 0.91 (m), r = 0.92 (f)) or anthropometry (SCAT-BMI: r = 0.93 (m, f)). VAT was correlated to VAT at umbilicus (r = 0.71 (m), r = 0.94 (f)) but only weakly to anthropometry.<h4>Conclusions</h4>Anthropometric measures and single-slice MRI can accurately predict TAT/SCAT which cannot be improved by evaluation of 5-slice stacks. Prediction of VAT by 5-slice stack/single-slice MRI protocols seems only to be accurate in females. Anthropometry cannot be reliably used for prediction of VAT in both genders. Thus, MRI seems to be necessary for quantification of VAT in overweight/obese adolescents of both genders.
Addresses
  • Section on Experimental Radiology, University Hospital Tübingen, Hoppe-Seyler-Str 3, 72076 Tübingen, Germany. Fabian.Springer@med.uni-tuebingen.de
Autoren
  • Fabian Springer
  • Stefan Ehehalt
  • Julia Sommer
  • Verena Ballweg
  • Jürgen Machann
  • Gerhard Binder
  • Claus D Claussen
  • Fritz Schick
  • DISKUS-Study Group
DOI
10.1016/j.ejrad.2011.04.006
eISSN
1872-7727
Externe Identifier
  • PubMed Identifier: 21543171
Open access
false
ISSN
0720-048X
Ausgabe der Veröffentlichung
7
Zeitschrift
European journal of radiology
Schlüsselwörter
  • DISKUS-Study Group
  • Adipose Tissue
  • Humans
  • Obesity
  • Magnetic Resonance Imaging
  • Anthropometry
  • Body Mass Index
  • Linear Models
  • Predictive Value of Tests
  • Image Processing, Computer-Assisted
  • Adolescent
  • Child
  • Female
  • Male
  • Overweight
Sprache
eng
Medium
Print-Electronic
Online publication date
2011
Paginierung
1488 - 1494
Datum der Veröffentlichung
2012
Status
Published
Datum der Datenerfassung
2011
Titel
Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
81

Datenquelle: Europe PubMed Central

Abstract
OBJECTIVES: To evaluate 5-slice stack/single-slice MRI approaches and anthropometric measures as predictors for metabolically relevant whole-body adipose tissue (AT) compartments in overweight/obese adolescents. METHODS: Forty adolescents (22 males, age 11.4-16.1 years) were included with a BMI above the 90th percentile. Volumes of whole-body AT compartments, i.e. total AT (TAT), subcutaneous AT (SCAT) and visceral AT (VAT), were determined using a breath-hold T1-weighted-FSE-MR-sequence and semi-automated segmentation serving as the gold standard. SCAT, VAT and TAT was estimated by either axially oriented single-slices or 5-slice-stacks centred at specific anatomic landmarks (umbilicus, head of femur and humerus). Furthermore, anthropometric measures were also evaluated as predictors of whole-body AT compartments. RESULTS: Strong correlations were found for both genders between TAT/SCAT and single-slice evaluation (e.g. whole-body SCAT-SCAT at umbilicus level: r = 0.91 (m), r = 0.92 (f)) or anthropometry (SCAT-BMI: r = 0.93 (m, f)). VAT was correlated to VAT at umbilicus (r = 0.71 (m), r = 0.94 (f)) but only weakly to anthropometry. CONCLUSIONS: Anthropometric measures and single-slice MRI can accurately predict TAT/SCAT which cannot be improved by evaluation of 5-slice stacks. Prediction of VAT by 5-slice stack/single-slice MRI protocols seems only to be accurate in females. Anthropometry cannot be reliably used for prediction of VAT in both genders. Thus, MRI seems to be necessary for quantification of VAT in overweight/obese adolescents of both genders.
Date of acceptance
2011
Autoren
  • Fabian Springer
  • Stefan Ehehalt
  • Julia Sommer
  • Verena Ballweg
  • Jürgen Machann
  • Gerhard Binder
  • Claus D Claussen
  • Fritz Schick
  • DISKUS-Study Group
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/21543171
DOI
10.1016/j.ejrad.2011.04.006
eISSN
1872-7727
Ausgabe der Veröffentlichung
7
Zeitschrift
Eur J Radiol
Schlüsselwörter
  • Adipose Tissue
  • Adolescent
  • Anthropometry
  • Body Mass Index
  • Child
  • Female
  • Humans
  • Image Processing, Computer-Assisted
  • Linear Models
  • Magnetic Resonance Imaging
  • Male
  • Obesity
  • Overweight
  • Predictive Value of Tests
Sprache
eng
Country
Ireland
Paginierung
1488 - 1494
PII
S0720-048X(11)00383-4
Datum der Veröffentlichung
2012
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2012
Titel
Predicting volumes of metabolically important whole-body adipose tissue compartments in overweight and obese adolescents by different MRI approaches and anthropometry.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
81

Datenquelle: PubMed

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