Children's Cortisol and Cell-Free DNA Trajectories in Relation to Sedentary Behavior and Physical Activity in School: A Pilot Study

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Christoph Becker
  • Sebastian Schmidt
  • Elmo WI Neuberger
  • Peter Kirsch
  • Perikles Simone
  • Ulrich Dettweiler
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000460579600001&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.3389/fpubh.2019.00026
Externe Identifier
  • Clarivate Analytics Document Solution ID: HO0GJ
  • PubMed Identifier: 30873396
ISSN
2296-2565
Zeitschrift
FRONTIERS IN PUBLIC HEALTH
Schlüsselwörter
  • cortisol
  • cfDNA
  • physical activity
  • health
  • outdoor environment
  • Bayesian inference
Artikelnummer
ARTN 26
Datum der Veröffentlichung
2019
Status
Published
Titel
Children's Cortisol and Cell-Free DNA Trajectories in Relation to Sedentary Behavior and Physical Activity in School: A Pilot Study
Sub types
  • Article
Ausgabe der Zeitschrift
7

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Autoren
  • Christoph Becker
  • Sebastian Schmidt
  • Elmo WI Neuberger
  • Peter Kirsch
  • Perikles Simon
  • Ulrich Dettweiler
DOI
10.3389/fpubh.2019.00026
eISSN
2296-2565
Zeitschrift
Frontiers in Public Health
Online publication date
2019
Status
Published online
Herausgeber
Frontiers Media SA
Herausgeber URL
http://dx.doi.org/10.3389/fpubh.2019.00026
Datum der Datenerfassung
2020
Titel
Children's Cortisol and Cell-Free DNA Trajectories in Relation to Sedentary Behavior and Physical Activity in School: A Pilot Study
Ausgabe der Zeitschrift
7

Datenquelle: Crossref

Abstract
The worldwide prevalence of mental disorders in children and adolescents increased constantly. Additionally, the recommended amount of physical activity (PA) is not achieved by this age group. These circumstances are associated with negative impacts on their health status in later life and can lead to public health issues. The exposure to natural green environments (NGE) seems to be beneficial for human health. The compulsory school system offers great opportunities to reach every child with suitable health-related contents and interventions at an early stage. The concept of Education Outside the Classroom (EOtC) uses NGE and sets focus on PA. Therefore, EOtC might be a beneficial educational intervention to promote students health. The association between biological stress markers and sedentary behavior (SB) plus PA is insufficiently evaluated in school settings. This exploratory study aims to evaluate the association between students' cortisol, plus circulating cell-free deoxyribonucleic acid (cfDNA) levels, and their SB, light PA (LPA), and moderate-to-vigorous PA (MVPA). We assessed data from an EOtC program (intervention group [IG], <i>n</i> = 37; control group [CG], <i>n</i> = 11) in three seasons (fall/spring/summer) in outdoor lessons (IG) in a NGE and normal indoor lessons (CG). SB and PA were evaluated by accelerometry, and cortisol and cfDNA levels by saliva samples. Fitted Bayesian hierarchical linear models evaluated the association between cortisol and cfDNA, and compositional SB/LPA/MVPA. A steady decline of cortisol in the IG is associated with relatively high levels of LPA (posterior mean = -0.728; credible interval [CRI 95%]: -1.268; -0.190). SB and MVPA tended to exhibit a similar effect in the CG. A high amount of cfDNA is positively associated with a relatively high amount of SB in the IG (posterior mean, 1.285; CRI: 0.390; 2.191), the same association is likely for LPA and MVPA in both groups. To conclude, LPA seems to support a healthy cortisol decrease in children during outdoor lessons in NGEs. Associations between cfDNA and SB/PA need to be evaluated in further research. This study facilitates the formulation of straightforward and directed hypotheses for further research with a focus on the potential health promotion of EOtC.
Addresses
  • Department of Sport and Health Sciences, Technical University of Munich, Munich, Germany.
Autoren
  • Christoph Becker
  • Sebastian Schmidt
  • Elmo WI Neuberger
  • Peter Kirsch
  • Perikles Simon
  • Ulrich Dettweiler
DOI
10.3389/fpubh.2019.00026
eISSN
2296-2565
Externe Identifier
  • PubMed Identifier: 30873396
  • PubMed Central ID: PMC6400867
Funding acknowledgements
  • Dietmar Hopp Stiftung:
Open access
true
ISSN
2296-2565
Zeitschrift
Frontiers in public health
Sprache
eng
Medium
Electronic-eCollection
Online publication date
2019
Open access status
Open Access
Paginierung
26
Datum der Veröffentlichung
2019
Status
Published
Publisher licence
CC BY
Datum der Datenerfassung
2019
Titel
Children's Cortisol and Cell-Free DNA Trajectories in Relation to Sedentary Behavior and Physical Activity in School: A Pilot Study.
Sub types
  • research-article
  • Journal Article
Ausgabe der Zeitschrift
7

Files

https://www.frontiersin.org/articles/10.3389/fpubh.2019.00026/pdf https://europepmc.org/articles/PMC6400867?pdf=render

Datenquelle: Europe PubMed Central

Abstract
The worldwide prevalence of mental disorders in children and adolescents increased constantly. Additionally, the recommended amount of physical activity (PA) is not achieved by this age group. These circumstances are associated with negative impacts on their health status in later life and can lead to public health issues. The exposure to natural green environments (NGE) seems to be beneficial for human health. The compulsory school system offers great opportunities to reach every child with suitable health-related contents and interventions at an early stage. The concept of Education Outside the Classroom (EOtC) uses NGE and sets focus on PA. Therefore, EOtC might be a beneficial educational intervention to promote students health. The association between biological stress markers and sedentary behavior (SB) plus PA is insufficiently evaluated in school settings. This exploratory study aims to evaluate the association between students' cortisol, plus circulating cell-free deoxyribonucleic acid (cfDNA) levels, and their SB, light PA (LPA), and moderate-to-vigorous PA (MVPA). We assessed data from an EOtC program (intervention group [IG], n = 37; control group [CG], n = 11) in three seasons (fall/spring/summer) in outdoor lessons (IG) in a NGE and normal indoor lessons (CG). SB and PA were evaluated by accelerometry, and cortisol and cfDNA levels by saliva samples. Fitted Bayesian hierarchical linear models evaluated the association between cortisol and cfDNA, and compositional SB/LPA/MVPA. A steady decline of cortisol in the IG is associated with relatively high levels of LPA (posterior mean = -0.728; credible interval [CRI 95%]: -1.268; -0.190). SB and MVPA tended to exhibit a similar effect in the CG. A high amount of cfDNA is positively associated with a relatively high amount of SB in the IG (posterior mean, 1.285; CRI: 0.390; 2.191), the same association is likely for LPA and MVPA in both groups. To conclude, LPA seems to support a healthy cortisol decrease in children during outdoor lessons in NGEs. Associations between cfDNA and SB/PA need to be evaluated in further research. This study facilitates the formulation of straightforward and directed hypotheses for further research with a focus on the potential health promotion of EOtC.
Date of acceptance
2019
Autoren
  • Christoph Becker
  • Sebastian Schmidt
  • Elmo WI Neuberger
  • Peter Kirsch
  • Perikles Simon
  • Ulrich Dettweiler
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/30873396
DOI
10.3389/fpubh.2019.00026
Externe Identifier
  • PubMed Central ID: PMC6400867
ISSN
2296-2565
Zeitschrift
Front Public Health
Schlüsselwörter
  • Bayesian inference
  • cfDNA
  • cortisol
  • health
  • outdoor environment
  • physical activity
Sprache
eng
Country
Switzerland
Paginierung
26
Datum der Veröffentlichung
2019
Status
Published online
Titel
Children's Cortisol and Cell-Free DNA Trajectories in Relation to Sedentary Behavior and Physical Activity in School: A Pilot Study.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
7

Datenquelle: PubMed

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