Antimicrobial Activity of Polyoxometalate Ionic Liquids against Clinically Relevant Pathogens

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Anna-Liisa Kubo
  • Lea Kremer
  • Sven Herrmann
  • Scott G Mitchell
  • Olesja M Bondarenko
  • Anne Kahru
  • Carsten Streb
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000405185000008&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1002/cplu.201700251
Externe Identifier
  • Clarivate Analytics Document Solution ID: FA1FP
  • PubMed Identifier: 31961570
ISSN
2192-6506
Ausgabe der Veröffentlichung
6
Zeitschrift
CHEMPLUSCHEM
Schlüsselwörter
  • antimicrobial agents
  • ionic liquids
  • materials chemistry
  • metal oxides
  • polyoxometalates
Paginierung
867 - 871
Datum der Veröffentlichung
2017
Status
Published
Titel
Antimicrobial Activity of Polyoxometalate Ionic Liquids against Clinically Relevant Pathogens
Sub types
  • Article
Ausgabe der Zeitschrift
82

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Abstract
<jats:title>Abstract</jats:title><jats:p>The activity of a new class of antimicrobials—polyoxometalate ionic liquids (POM‐ILs)—is systematically investigated. The prototype POM‐ILs feature Keggin‐type anions (α‐SiW<jats:sub>11</jats:sub>O<jats:sub>39</jats:sub><jats:sup>8−</jats:sup>) and tetraalkylammonium ions as active cationic species. Antimicrobial tests of the POM‐ILs against important human pathogens show that variation of the alkyl chain length of the cation leads to significant changes in antimicrobial activity against the medically relevant Gram‐negative bacteria <jats:italic>Escherichia coli</jats:italic> and <jats:italic>Pseudomonas aeruginosa,</jats:italic> and especially against the Gram‐positive <jats:italic>Staphylococcus aureus</jats:italic>. Owing to the unique materials properties of the POM‐ILs, such as high viscosity and water immiscibility, applications of antimicrobial surface coatings against airborne pathogens or for water decontamination can be envisaged. Furthermore, the combination of antimicrobially active cations with POM anions might afford new POM‐ILs with two active components.</jats:p>
Autoren
  • Anna‐Liisa Kubo
  • Lea Kremer
  • Sven Herrmann
  • Scott G Mitchell
  • Olesja M Bondarenko
  • Anne Kahru
  • Carsten Streb
DOI
10.1002/cplu.201700251
eISSN
2192-6506
ISSN
2192-6506
Ausgabe der Veröffentlichung
6
Zeitschrift
ChemPlusChem
Sprache
en
Online publication date
2017
Paginierung
867 - 871
Datum der Veröffentlichung
2017
Status
Published
Herausgeber
Wiley
Herausgeber URL
http://dx.doi.org/10.1002/cplu.201700251
Datum der Datenerfassung
2023
Titel
Antimicrobial Activity of Polyoxometalate Ionic Liquids against Clinically Relevant Pathogens
Ausgabe der Zeitschrift
82

Datenquelle: Crossref

Abstract
The activity of a new class of antimicrobials-polyoxometalate ionic liquids (POM-ILs)-is systematically investigated. The prototype POM-ILs feature Keggin-type anions (α-SiW<sub>11</sub> O<sub>39</sub> <sup>8-</sup> ) and tetraalkylammonium ions as active cationic species. Antimicrobial tests of the POM-ILs against important human pathogens show that variation of the alkyl chain length of the cation leads to significant changes in antimicrobial activity against the medically relevant Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa, and especially against the Gram-positive Staphylococcus aureus. Owing to the unique materials properties of the POM-ILs, such as high viscosity and water immiscibility, applications of antimicrobial surface coatings against airborne pathogens or for water decontamination can be envisaged. Furthermore, the combination of antimicrobially active cations with POM anions might afford new POM-ILs with two active components.
Addresses
  • National Institute of Chemical Physics and Biophysics, Laboratory of Environmental Toxicology, Akadeemia tee 23, Tallinn, 12618, Estonia.
Autoren
  • Anna-Liisa Kubo
  • Lea Kremer
  • Sven Herrmann
  • Scott G Mitchell
  • Olesja M Bondarenko
  • Anne Kahru
  • Carsten Streb
DOI
10.1002/cplu.201700251
eISSN
2192-6506
Externe Identifier
  • PubMed Identifier: 31961570
Funding acknowledgements
  • European Cooperation in Science and Technology (COST): CM1203
  • Fonds der chemischen Industrie:
  • Estonian Ministry of Education and Research: IUT23-5; PUT1015
Open access
false
ISSN
2192-6506
Ausgabe der Veröffentlichung
6
Zeitschrift
ChemPlusChem
Sprache
eng
Medium
Print
Paginierung
867 - 871
Datum der Veröffentlichung
2017
Status
Published
Datum der Datenerfassung
2020
Titel
Antimicrobial Activity of Polyoxometalate Ionic Liquids against Clinically Relevant Pathogens.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
82

Datenquelle: Europe PubMed Central

Abstract
The activity of a new class of antimicrobials-polyoxometalate ionic liquids (POM-ILs)-is systematically investigated. The prototype POM-ILs feature Keggin-type anions (α-SiW11 O39 8- ) and tetraalkylammonium ions as active cationic species. Antimicrobial tests of the POM-ILs against important human pathogens show that variation of the alkyl chain length of the cation leads to significant changes in antimicrobial activity against the medically relevant Gram-negative bacteria Escherichia coli and Pseudomonas aeruginosa, and especially against the Gram-positive Staphylococcus aureus. Owing to the unique materials properties of the POM-ILs, such as high viscosity and water immiscibility, applications of antimicrobial surface coatings against airborne pathogens or for water decontamination can be envisaged. Furthermore, the combination of antimicrobially active cations with POM anions might afford new POM-ILs with two active components.
Autoren
  • Anna-Liisa Kubo
  • Lea Kremer
  • Sven Herrmann
  • Scott G Mitchell
  • Olesja M Bondarenko
  • Anne Kahru
  • Carsten Streb
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/31961570
DOI
10.1002/cplu.201700251
eISSN
2192-6506
Funding acknowledgements
  • Estonian Ministry of Education and Research: IUT23-5; PUT1015
  • Fonds der chemischen Industrie:
  • European Cooperation in Science and Technology (COST): CM1203
Ausgabe der Veröffentlichung
6
Zeitschrift
Chempluschem
Schlüsselwörter
  • antimicrobial agents
  • ionic liquids
  • materials chemistry
  • metal oxides
  • polyoxometalates
Sprache
eng
Country
Germany
Paginierung
867 - 871
Datum der Veröffentlichung
2017
Status
Published
Titel
Antimicrobial Activity of Polyoxometalate Ionic Liquids against Clinically Relevant Pathogens.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
82

Datenquelle: PubMed

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