Effect of chain topology on the self-organization and dynamics of block copolypeptides: From diblock copolymers to stars
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- A Gitsas
- G Floudas
- M Mondeshki
- H-J Butt
- HW Spiess
- H Iatrou
- N Hadjichristidis
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000257639500032&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1021/bm800221n
- eISSN
- 1526-4602
- Externe Identifier
- Clarivate Analytics Document Solution ID: 326DX
- PubMed Identifier: 18564873
- ISSN
- 1525-7797
- Ausgabe der Veröffentlichung
- 7
- Zeitschrift
- BIOMACROMOLECULES
- Paginierung
- 1959 - 1966
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Titel
- Effect of chain topology on the self-organization and dynamics of block copolypeptides: From diblock copolymers to stars
- Sub types
- Article
- Ausgabe der Zeitschrift
- 9
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- A Gitsas
- G Floudas
- M Mondeshki
- H-J Butt
- HW Spiess
- H Iatrou
- N Hadjichristidis
- DOI
- 10.1021/bm800221n
- eISSN
- 1526-4602
- ISSN
- 1525-7797
- Ausgabe der Veröffentlichung
- 7
- Zeitschrift
- Biomacromolecules
- Sprache
- en
- Online publication date
- 2008
- Paginierung
- 1959 - 1966
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Herausgeber
- American Chemical Society (ACS)
- Herausgeber URL
- http://dx.doi.org/10.1021/bm800221n
- Datum der Datenerfassung
- 2024
- Titel
- Effect of Chain Topology on the Self-Organization and Dynamics of Block Copolypeptides: From Diblock Copolymers to Stars
- Ausgabe der Zeitschrift
- 9
Datenquelle: Crossref
- Abstract
- The effect of chain topology on (i) the peptide secondary structure, (ii) the nanophase self-assembly, and (iii) the local segmental and global peptide relaxations has been studied in a series of model diblock and 3-arm star copolypeptides of poly(epsilon-carbobenzyloxy-L-lysine) (PZLL) and poly(gamma-benzyl-L-glutamate) (PBLG) with PZLL forming the core. Diblock copolypeptides are nanophase separated with PBLG and PZLL domains comprising alpha-helices packed in a hexagonal lattice. Star copolypeptides are only weakly phase separated, comprising PBLG and PZLL alpha-helices in a pseudohexagonal lattice. Phase mixing has profound consequences on the local and global dynamics. The relaxation of the peptide secondary structure speeds up, and the helix persistence length is further reduced in the stars, signifying an increased concentration of helical defects.
- Addresses
- Department of Physics, University of Ioannina, Post Office Box 1186, 45110 Ioannina, Greece. gfloudas@cc.uoi.gr
- Autoren
- A Gitsas
- G Floudas
- M Mondeshki
- H-J Butt
- HW Spiess
- H Iatrou
- N Hadjichristidis
- DOI
- 10.1021/bm800221n
- eISSN
- 1526-4602
- Externe Identifier
- PubMed Identifier: 18564873
- Open access
- false
- ISSN
- 1525-7797
- Ausgabe der Veröffentlichung
- 7
- Zeitschrift
- Biomacromolecules
- Schlüsselwörter
- Polymers
- Polyglutamic Acid
- Polylysine
- Peptides
- Protein Structure, Secondary
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2008
- Paginierung
- 1959 - 1966
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Datum der Datenerfassung
- 2008
- Titel
- Effect of chain topology on the self-organization and dynamics of block copolypeptides: from diblock copolymers to stars.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 9
Datenquelle: Europe PubMed Central
- Abstract
- The effect of chain topology on (i) the peptide secondary structure, (ii) the nanophase self-assembly, and (iii) the local segmental and global peptide relaxations has been studied in a series of model diblock and 3-arm star copolypeptides of poly(epsilon-carbobenzyloxy-L-lysine) (PZLL) and poly(gamma-benzyl-L-glutamate) (PBLG) with PZLL forming the core. Diblock copolypeptides are nanophase separated with PBLG and PZLL domains comprising alpha-helices packed in a hexagonal lattice. Star copolypeptides are only weakly phase separated, comprising PBLG and PZLL alpha-helices in a pseudohexagonal lattice. Phase mixing has profound consequences on the local and global dynamics. The relaxation of the peptide secondary structure speeds up, and the helix persistence length is further reduced in the stars, signifying an increased concentration of helical defects.
- Autoren
- A Gitsas
- G Floudas
- M Mondeshki
- H-J Butt
- HW Spiess
- H Iatrou
- N Hadjichristidis
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/18564873
- DOI
- 10.1021/bm800221n
- eISSN
- 1526-4602
- Ausgabe der Veröffentlichung
- 7
- Zeitschrift
- Biomacromolecules
- Schlüsselwörter
- Peptides
- Polyglutamic Acid
- Polylysine
- Polymers
- Protein Structure, Secondary
- Sprache
- eng
- Country
- United States
- Paginierung
- 1959 - 1966
- Datum der Veröffentlichung
- 2008
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2008
- Titel
- Effect of chain topology on the self-organization and dynamics of block copolypeptides: from diblock copolymers to stars.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 9
Datenquelle: PubMed
- Beziehungen:
- Eigentum von