Somatosensory amplification moderates the efficacy of internet-delivered CBT for somatic symptom distress in emerging adults: Exploratory analysis of a randomized controlled trial

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Severin Hennemann
  • Michael Witthoeft
  • Maria Kleinstaeuber
  • Katja Boehme
  • Harald Baumeister
  • David Daniel Ebert
  • Thomas Probst
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000793129100003&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1016/j.jpsychores.2022.110761
eISSN
1879-1360
Externe Identifier
  • Clarivate Analytics Document Solution ID: 1C4ZL
  • PubMed Identifier: 35182889
ISSN
0022-3999
Zeitschrift
JOURNAL OF PSYCHOSOMATIC RESEARCH
Schlüsselwörter
  • Internet-delivered cognitive behavioral therapy
  • Randomized controlled trial
  • Moderators
  • Somatic symptom distress
  • Somatosensory amplification
Artikelnummer
ARTN 110761
Datum der Veröffentlichung
2022
Status
Published
Titel
Somatosensory amplification moderates the efficacy of internet-delivered CBT for somatic symptom distress in emerging adults: Exploratory analysis of a randomized controlled trial
Sub types
  • Article
Ausgabe der Zeitschrift
155

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Autoren
  • Severin Hennemann
  • Michael Witthöft
  • Maria Kleinstäuber
  • Katja Böhme
  • Harald Baumeister
  • David Daniel Ebert
  • Thomas Probst
DOI
10.1016/j.jpsychores.2022.110761
ISSN
0022-3999
Zeitschrift
Journal of Psychosomatic Research
Sprache
en
Artikelnummer
110761
Paginierung
110761 - 110761
Datum der Veröffentlichung
2022
Status
Published
Herausgeber
Elsevier BV
Herausgeber URL
http://dx.doi.org/10.1016/j.jpsychores.2022.110761
Datum der Datenerfassung
2022
Titel
Somatosensory amplification moderates the efficacy of internet-delivered CBT for somatic symptom distress in emerging adults: Exploratory analysis of a randomized controlled trial
Ausgabe der Zeitschrift
155

Datenquelle: Crossref

Abstract
<h4>Objective</h4>While studies mainly provide positive evidence for the efficacy of internet-delivered cognitive-behavioral therapy (ICBT) for various persistent somatic symptoms, it remains largely unclear for whom these interventions work or not. This exploratory analysis aimed to identify moderators for the outcome between ICBT for somatic symptom distres and a waitlist control group (WL) in a vulnerable target group of emerging adults.<h4>Methods</h4>Based on data from a randomized controlled trial on 156 university students with varying degrees of somatic symptom distress who were allocated to either an eight-week, therapist guided ICBT (iSOMA) or to the WL, we examined pretreatment demographic characteristics, health-related variables (e.g., somatic symptom duration), mental distress (e.g., depression, anxiety) and cognitive-emotional factors (emotional reactivity, somatosensory amplification) as candidate moderators of the outcome, somatic symptom distress (assessed by the Patient Health Questionnaire, PHQ-15) from pre- to posttreatment.<h4>Results</h4>Somatosensory amplification (assessed by the Somatosensory Amplification Scale, SSAS) moderated the outcome in favor of iSOMA (B = -0.17, SE = 0.08, p = 0.031), i.e., higher pretreatment somatosensory amplification was associated with better outcome in the active compared to the control intervention. No significant moderation effects were found among demographic characteristics, health-related variables, or mental distress.<h4>Conclusion</h4>Our findings suggest that an internet-delivered CBT for somatic symptom distress should be preferred over no active treatment particularly in individuals with moderate to high levels of somatosensory amplification, which as a next step should be tested against further treatments and in clinical populations.<h4>Trial registration</h4>German Clinical Trials Register (DRKS00014375).
Addresses
  • Johannes Gutenberg University Mainz, Department of Clinical Psychology, Psychotherapy and Experimental Psychopathology, Mainz, Germany. Electronic address: s.hennemann@uni-mainz.de.
Autoren
  • Severin Hennemann
  • Michael Witthöft
  • Maria Kleinstäuber
  • Katja Böhme
  • Harald Baumeister
  • David Daniel Ebert
  • Thomas Probst
DOI
10.1016/j.jpsychores.2022.110761
eISSN
1879-1360
Externe Identifier
  • PubMed Identifier: 35182889
Open access
false
ISSN
0022-3999
Zeitschrift
Journal of psychosomatic research
Schlüsselwörter
  • Humans
  • Treatment Outcome
  • Anxiety Disorders
  • Internet
  • Adult
  • Medically Unexplained Symptoms
  • Cognitive Behavioral Therapy
Sprache
eng
Medium
Print-Electronic
Online publication date
2022
Paginierung
110761
Datum der Veröffentlichung
2022
Status
Published
Datum der Datenerfassung
2022
Titel
Somatosensory amplification moderates the efficacy of internet-delivered CBT for somatic symptom distress in emerging adults: Exploratory analysis of a randomized controlled trial.
Sub types
  • Research Support, Non-U.S. Gov't
  • Randomized Controlled Trial
  • Journal Article
Ausgabe der Zeitschrift
155

Datenquelle: Europe PubMed Central

Abstract
OBJECTIVE: While studies mainly provide positive evidence for the efficacy of internet-delivered cognitive-behavioral therapy (ICBT) for various persistent somatic symptoms, it remains largely unclear for whom these interventions work or not. This exploratory analysis aimed to identify moderators for the outcome between ICBT for somatic symptom distres and a waitlist control group (WL) in a vulnerable target group of emerging adults. METHODS: Based on data from a randomized controlled trial on 156 university students with varying degrees of somatic symptom distress who were allocated to either an eight-week, therapist guided ICBT (iSOMA) or to the WL, we examined pretreatment demographic characteristics, health-related variables (e.g., somatic symptom duration), mental distress (e.g., depression, anxiety) and cognitive-emotional factors (emotional reactivity, somatosensory amplification) as candidate moderators of the outcome, somatic symptom distress (assessed by the Patient Health Questionnaire, PHQ-15) from pre- to posttreatment. RESULTS: Somatosensory amplification (assessed by the Somatosensory Amplification Scale, SSAS) moderated the outcome in favor of iSOMA (B = -0.17, SE = 0.08, p = 0.031), i.e., higher pretreatment somatosensory amplification was associated with better outcome in the active compared to the control intervention. No significant moderation effects were found among demographic characteristics, health-related variables, or mental distress. CONCLUSION: Our findings suggest that an internet-delivered CBT for somatic symptom distress should be preferred over no active treatment particularly in individuals with moderate to high levels of somatosensory amplification, which as a next step should be tested against further treatments and in clinical populations. TRIAL REGISTRATION: German Clinical Trials Register (DRKS00014375).
Date of acceptance
2022
Autoren
  • Severin Hennemann
  • Michael Witthöft
  • Maria Kleinstäuber
  • Katja Böhme
  • Harald Baumeister
  • David Daniel Ebert
  • Thomas Probst
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/35182889
DOI
10.1016/j.jpsychores.2022.110761
eISSN
1879-1360
Zeitschrift
J Psychosom Res
Schlüsselwörter
  • Internet-delivered cognitive behavioral therapy
  • Moderators
  • Randomized controlled trial
  • Somatic symptom distress
  • Somatosensory amplification
  • Adult
  • Anxiety Disorders
  • Cognitive Behavioral Therapy
  • Humans
  • Internet
  • Medically Unexplained Symptoms
  • Treatment Outcome
Sprache
eng
Country
England
Paginierung
110761
PII
S0022-3999(22)00046-0
Datum der Veröffentlichung
2022
Status
Published
Datum, an dem der Datensatz öffentlich gemacht wurde
2022
Titel
Somatosensory amplification moderates the efficacy of internet-delivered CBT for somatic symptom distress in emerging adults: Exploratory analysis of a randomized controlled trial.
Sub types
  • Journal Article
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
Ausgabe der Zeitschrift
155

Datenquelle: PubMed

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