α-Cyanation of Aromatic Tertiary Amines using Ferricyanide as a Non-Toxic Cyanide Source

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Alexander M Nauth
  • Nicola Otto
  • Till Opatz
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000368342400003&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1002/adsc.201500698
eISSN
1615-4169
Externe Identifier
  • Clarivate Analytics Document Solution ID: DB2MH
ISSN
1615-4150
Ausgabe der Veröffentlichung
16-17
Zeitschrift
ADVANCED SYNTHESIS & CATALYSIS
Schlüsselwörter
  • amines
  • C-H activation
  • cross-dehydrogenative coupling
  • cyanides
  • green chemistry
Paginierung
3424 - 3428
Datum der Veröffentlichung
2015
Status
Published
Titel
α-Cyanation of Aromatic Tertiary Amines using Ferricyanide as a Non-Toxic Cyanide Source
Sub types
  • Article
Ausgabe der Zeitschrift
357

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Abstract
<jats:title>Abstract</jats:title><jats:p>The reaction of aromatic tertiary amines with potassium ferricyanide directly provides the useful α‐amino nitriles. The inexpensive iron complex functions both as an oxidant and as a cyanide source. The presence of molecular oxygen speeds up the reaction which can be performed in aqueous <jats:italic>tert</jats:italic>‐butanol or even in ethanol‐based mixtures like Tequila. While amine cyanations usually employ highly toxic cyanide sources, potassium ferricyanide is even less toxic than table salt. No expensive metal complexes are required as catalysts and the co‐product of the cyanation, Prussian blue, has no known toxicity and is rather used as an antidote.</jats:p><jats:p><jats:boxed-text content-type="graphic" position="anchor"><jats:graphic xmlns:xlink="http://www.w3.org/1999/xlink" mimetype="image/gif" position="anchor" specific-use="enlarged-web-image" xlink:href="graphic/mcontent.gif"><jats:alt-text>magnified image</jats:alt-text></jats:graphic></jats:boxed-text></jats:p>
Autoren
  • Alexander M Nauth
  • Nicola Otto
  • Till Opatz
DOI
10.1002/adsc.201500698
eISSN
1615-4169
ISSN
1615-4150
Ausgabe der Veröffentlichung
16-17
Zeitschrift
Advanced Synthesis &amp; Catalysis
Sprache
en
Online publication date
2015
Paginierung
3424 - 3428
Datum der Veröffentlichung
2015
Status
Published
Herausgeber
Wiley
Herausgeber URL
http://dx.doi.org/10.1002/adsc.201500698
Datum der Datenerfassung
2023
Titel
α‐Cyanation of Aromatic Tertiary Amines using Ferricyanide as a Non‐Toxic Cyanide Source
Ausgabe der Zeitschrift
357

Datenquelle: Crossref

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