Neo-clerodane diterpenoids from Conyza pyrrhopappa Sch.Bip. ex A.Rich
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Gabin Thierry M Bitchagno
- Anja Schueffler
- Ingrid K Simo
- Matthias Krumb
- Pierre Tane
- Till Opatz
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000496635900001&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1080/14786419.2019.1690490
- eISSN
- 1478-6427
- Externe Identifier
- Clarivate Analytics Document Solution ID: UZ3OG
- PubMed Identifier: 31726857
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 19
- Zeitschrift
- NATURAL PRODUCT RESEARCH
- Schlüsselwörter
- Isolation
- Structure elucidation
- Neo-clerodanes
- Conyza pyrrhopappa
- Asteraceae
- Cytotoxicity
- Antimicrobial
- Paginierung
- 3210 - 3219
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Titel
- <i>Neo</i>-clerodane diterpenoids from <i>Conyza pyrrhopappa</i> Sch.Bip. ex A.Rich
- Sub types
- Article
- Ausgabe der Zeitschrift
- 35
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Gabin Thierry M Bitchagno
- Anja Schüffler
- Ingrid K Simo
- Matthias Krumb
- Pierre Tane
- Till Opatz
- DOI
- 10.1080/14786419.2019.1690490
- eISSN
- 1478-6427
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 19
- Zeitschrift
- Natural Product Research
- Sprache
- en
- Online publication date
- 2019
- Paginierung
- 3210 - 3219
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Herausgeber
- Informa UK Limited
- Herausgeber URL
- http://dx.doi.org/10.1080/14786419.2019.1690490
- Datum der Datenerfassung
- 2022
- Titel
- <i>Neo</i>-clerodane diterpenoids from <i>Conyza pyrrhopappa</i> Sch.Bip. ex A.Rich
- Ausgabe der Zeitschrift
- 35
Datenquelle: Crossref
- Abstract
- Two hitherto unknown <i>neo</i>-clerodane-type diterpenoids along with twelve known compounds have been isolated from <i>Conyza pyrrhopappa</i> Sch.Bip. ex A.Rich, a medicinal plant traditionally used across tropical Africa to relieve fever. The structures of isolates have been elucidated by a combination of spectroscopic techniques. The crude extract and the isolated compounds were evaluated in the Hela-S3 cell line and in a panel of microorganisms (bacteria and fungi) at concentrations up to 50 µg/mL. The new compounds were inactive while the pentamethylated flavonoids showed low to significant activity against the cancer cell line used. However, none of the samples showed any activity against the tested microorganisms at this concentration. The present manuscript is the first investigation of the cytotoxicity of phytochemicals and extract from <i>C. pyrrhopappa</i>.
- Addresses
- Department of Chemistry, University of Dschang, Dschang, Cameroon.
- Autoren
- Gabin Thierry M Bitchagno
- Anja Schüffler
- Ingrid K Simo
- Matthias Krumb
- Pierre Tane
- Till Opatz
- DOI
- 10.1080/14786419.2019.1690490
- eISSN
- 1478-6427
- Externe Identifier
- PubMed Identifier: 31726857
- Funding acknowledgements
- German Academic Exchange Service: 57381410
- University Johannes Gutenberg of Mainz:
- Open access
- false
- ISSN
- 1478-6419
- Ausgabe der Veröffentlichung
- 19
- Zeitschrift
- Natural product research
- Schlüsselwörter
- Hela Cells
- Humans
- Conyza
- Plants, Medicinal
- Diterpenes, Clerodane
- Plant Extracts
- Molecular Structure
- Phytochemicals
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2019
- Paginierung
- 3210 - 3219
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Datum der Datenerfassung
- 2019
- Titel
- <i>Neo</i>-clerodane diterpenoids from <i>Conyza pyrrhopappa</i> Sch.Bip. ex A.Rich.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 35
Datenquelle: Europe PubMed Central
- Abstract
- Two hitherto unknown neo-clerodane-type diterpenoids along with twelve known compounds have been isolated from Conyza pyrrhopappa Sch.Bip. ex A.Rich, a medicinal plant traditionally used across tropical Africa to relieve fever. The structures of isolates have been elucidated by a combination of spectroscopic techniques. The crude extract and the isolated compounds were evaluated in the Hela-S3 cell line and in a panel of microorganisms (bacteria and fungi) at concentrations up to 50 µg/mL. The new compounds were inactive while the pentamethylated flavonoids showed low to significant activity against the cancer cell line used. However, none of the samples showed any activity against the tested microorganisms at this concentration. The present manuscript is the first investigation of the cytotoxicity of phytochemicals and extract from C. pyrrhopappa.
- Autoren
- Gabin Thierry M Bitchagno
- Anja Schüffler
- Ingrid K Simo
- Matthias Krumb
- Pierre Tane
- Till Opatz
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/31726857
- DOI
- 10.1080/14786419.2019.1690490
- eISSN
- 1478-6427
- Ausgabe der Veröffentlichung
- 19
- Zeitschrift
- Nat Prod Res
- Schlüsselwörter
- Antimicrobial
- Asteraceae
- Conyza pyrrhopappa
- Cytotoxicity
- Isolation
- Neo-clerodanes
- Structure elucidation
- Conyza
- Diterpenes, Clerodane
- HeLa Cells
- Humans
- Molecular Structure
- Phytochemicals
- Plant Extracts
- Plants, Medicinal
- Sprache
- eng
- Country
- England
- Paginierung
- 3210 - 3219
- Datum der Veröffentlichung
- 2021
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2021
- Titel
- Neo-clerodane diterpenoids from Conyza pyrrhopappa Sch.Bip. ex A.Rich.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 35
Datenquelle: PubMed
- Beziehungen:
- Eigentum von