A systematic diagnostic and therapeutic approach for the treatment of patients after cardio-pulmonary resuscitation: a prospective evaluation of 212 patients over 5 years
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Hubertus von Korn
- Victor Stefan
- Reyn van Ewijk
- Kamalesh Chakraborty
- Burkhard Sanwald
- Jan Hemker
- Ulrich Hink
- Marc Ohlow
- Bernward Lauer
- Dierk Vagts
- Stefan Gruene
- Thomas Muenzel
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000401633900011&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1007/s11739-016-1480-0
- eISSN
- 1970-9366
- Externe Identifier
- Clarivate Analytics Document Solution ID: EV3CF
- PubMed Identifier: 27273245
- ISSN
- 1828-0447
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- INTERNAL AND EMERGENCY MEDICINE
- Schlüsselwörter
- Therapy and diagnosis
- Resuscitation
- Paginierung
- 503 - 511
- Datum der Veröffentlichung
- 2017
- Status
- Published
- Titel
- A systematic diagnostic and therapeutic approach for the treatment of patients after cardio-pulmonary resuscitation: a prospective evaluation of 212 patients over 5 years
- Sub types
- Article
- Ausgabe der Zeitschrift
- 12
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Hubertus von Korn
- Victor Stefan
- Reyn van Ewijk
- Kamalesh Chakraborty
- Burkhard Sanwald
- Jan Hemker
- Ulrich Hink
- Marc Ohlow
- Bernward Lauer
- Dierk Vagts
- Stefan Gruene
- Thomas Münzel
- DOI
- 10.1007/s11739-016-1480-0
- eISSN
- 1970-9366
- ISSN
- 1828-0447
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Internal and Emergency Medicine
- Sprache
- en
- Online publication date
- 2016
- Paginierung
- 503 - 511
- Datum der Veröffentlichung
- 2017
- Status
- Published
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1007/s11739-016-1480-0
- Datum der Datenerfassung
- 2017
- Titel
- A systematic diagnostic and therapeutic approach for the treatment of patients after cardio-pulmonary resuscitation: a prospective evaluation of 212 patients over 5 years
- Ausgabe der Zeitschrift
- 12
Datenquelle: Crossref
- Abstract
- A literature on systematic treatment protocols for patients after resuscitation for cardiac arrest is lacking. We evaluated a systematic protocol, including ECG, echocardiogram, urgent cardiac catheterisation ("STEMI-like" workflow), CT scans, laboratory findings, IABP, hypothermia, and cMRI, prospectively over 5 years. The primary endpoint was the Cerebral Performance Category Scale (CPCS). During the period from January 2008 to December 2012, 212 patients were included. The mean age was 66.7 years, n = 151 (71.2 %) were male, mean time from the first medical contact to start of catheterisation was 76.6 min, and ventricular fibrillation (VF) was present in n = 99 (46.7 %). A significant coronary artery stenosis was seen in n = 130 (61.3 %), PCI was performed in n = 101 (47.6 %), an ACS was found in n = 100 (47.2 %), n = 91 patients (42.9 %) had another cardiac cause, an extra-cardiac cause was found in n = 12 (5.7 %, mostly a cerebral process), and in 9 patients (4.3 %), no cause was identifiable. A significant difference in mortality was found for patients with TIMI flow 2/3 vs. 0/1 (65.4 vs. 95.7 %, p < 0.01). The difference of intra-aortic balloon pumping vs. no pumping was not significant, performing hypothermia reduced mortality significantly (52.7 vs. 68.2 %, p = 0.04). The survival rate was n = 76 (35.9 %), a CPCS of 1/2 was reached in n = 68 pts (32.1 %), patients with ongoing resuscitation had a 100 % mortality (n = 41), and VF had a lower mortality (54.6 vs. 72.6 %, p < 0.01). A systematic algorithm may improve the outcome of patients after reanimation compared with classically reported outcomes. The data are hypothesis generating for further studies.
- Addresses
- Department of Cardiology, Hetzelstift, Stiftstr. 10, 67434, Neustadt, Germany. h.vonkorn@new.marienhaus-gmbh.de.
- Autoren
- Hubertus von Korn
- Victor Stefan
- Reyn van Ewijk
- Kamalesh Chakraborty
- Burkhard Sanwald
- Jan Hemker
- Ulrich Hink
- Marc Ohlow
- Bernward Lauer
- Dierk Vagts
- Stefan Gruene
- Thomas Münzel
- DOI
- 10.1007/s11739-016-1480-0
- eISSN
- 1970-9366
- Externe Identifier
- PubMed Identifier: 27273245
- Open access
- false
- ISSN
- 1828-0447
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Internal and emergency medicine
- Schlüsselwörter
- Humans
- Treatment Outcome
- Cardiopulmonary Resuscitation
- Intra-Aortic Balloon Pumping
- Severity of Illness Index
- Chi-Square Distribution
- Survival Analysis
- Prospective Studies
- Time Factors
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Middle Aged
- Germany
- Female
- Male
- Out-of-Hospital Cardiac Arrest
- Cardiac Catheterization
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2016
- Paginierung
- 503 - 511
- Datum der Veröffentlichung
- 2017
- Status
- Published
- Datum der Datenerfassung
- 2016
- Titel
- A systematic diagnostic and therapeutic approach for the treatment of patients after cardio-pulmonary resuscitation: a prospective evaluation of 212 patients over 5 years.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 12
Datenquelle: Europe PubMed Central
- Abstract
- A literature on systematic treatment protocols for patients after resuscitation for cardiac arrest is lacking. We evaluated a systematic protocol, including ECG, echocardiogram, urgent cardiac catheterisation ("STEMI-like" workflow), CT scans, laboratory findings, IABP, hypothermia, and cMRI, prospectively over 5 years. The primary endpoint was the Cerebral Performance Category Scale (CPCS). During the period from January 2008 to December 2012, 212 patients were included. The mean age was 66.7 years, n = 151 (71.2 %) were male, mean time from the first medical contact to start of catheterisation was 76.6 min, and ventricular fibrillation (VF) was present in n = 99 (46.7 %). A significant coronary artery stenosis was seen in n = 130 (61.3 %), PCI was performed in n = 101 (47.6 %), an ACS was found in n = 100 (47.2 %), n = 91 patients (42.9 %) had another cardiac cause, an extra-cardiac cause was found in n = 12 (5.7 %, mostly a cerebral process), and in 9 patients (4.3 %), no cause was identifiable. A significant difference in mortality was found for patients with TIMI flow 2/3 vs. 0/1 (65.4 vs. 95.7 %, p < 0.01). The difference of intra-aortic balloon pumping vs. no pumping was not significant, performing hypothermia reduced mortality significantly (52.7 vs. 68.2 %, p = 0.04). The survival rate was n = 76 (35.9 %), a CPCS of 1/2 was reached in n = 68 pts (32.1 %), patients with ongoing resuscitation had a 100 % mortality (n = 41), and VF had a lower mortality (54.6 vs. 72.6 %, p < 0.01). A systematic algorithm may improve the outcome of patients after reanimation compared with classically reported outcomes. The data are hypothesis generating for further studies.
- Date of acceptance
- 2016
- Autoren
- Hubertus von Korn
- Victor Stefan
- Reyn van Ewijk
- Kamalesh Chakraborty
- Burkhard Sanwald
- Jan Hemker
- Ulrich Hink
- Marc Ohlow
- Bernward Lauer
- Dierk Vagts
- Stefan Gruene
- Thomas Münzel
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/27273245
- DOI
- 10.1007/s11739-016-1480-0
- eISSN
- 1970-9366
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Intern Emerg Med
- Schlüsselwörter
- Resuscitation
- Therapy and diagnosis
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Cardiac Catheterization
- Cardiopulmonary Resuscitation
- Chi-Square Distribution
- Female
- Germany
- Humans
- Intra-Aortic Balloon Pumping
- Male
- Middle Aged
- Out-of-Hospital Cardiac Arrest
- Prospective Studies
- Severity of Illness Index
- Survival Analysis
- Time Factors
- Treatment Outcome
- Sprache
- eng
- Country
- Italy
- Paginierung
- 503 - 511
- PII
- 10.1007/s11739-016-1480-0
- Datum der Veröffentlichung
- 2017
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2017
- Titel
- A systematic diagnostic and therapeutic approach for the treatment of patients after cardio-pulmonary resuscitation: a prospective evaluation of 212 patients over 5 years.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 12
Datenquelle: PubMed
- Beziehungen:
- Eigentum von