Ramadan Exposure In Utero and Child Mortality in Burkina Faso: Analysis of a Population-Based Cohort Including 41,025 Children
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Anja Schoeps
- Reyn van Ewijk
- Gisela Kynast-Wolf
- Eric Nebie
- Pascal Zabre
- Ali Sie
- Sabine Gabrysch
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000446084200004&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1093/aje/kwy091
- eISSN
- 1476-6256
- Externe Identifier
- Clarivate Analytics Document Solution ID: GV4QB
- PubMed Identifier: 29741574
- ISSN
- 0002-9262
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- AMERICAN JOURNAL OF EPIDEMIOLOGY
- Schlüsselwörter
- child mortality
- difference in differences
- population-based cohort
- prenatal exposure delayed effects
- pregnancy
- Ramadan
- sub-Saharan Africa
- Paginierung
- 2085 - 2092
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Titel
- Ramadan Exposure In Utero and Child Mortality in Burkina Faso: Analysis of a Population-Based Cohort Including 41,025 Children
- Sub types
- Article
- Ausgabe der Zeitschrift
- 187
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Anja Schoeps
- Reyn van Ewijk
- Gisela Kynast-Wolf
- Eric Nebié
- Pascal Zabré
- Ali Sié
- Sabine Gabrysch
- DOI
- 10.1093/aje/kwy091
- eISSN
- 1476-6256
- ISSN
- 0002-9262
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- American Journal of Epidemiology
- Sprache
- en
- Online publication date
- 2018
- Paginierung
- 2085 - 2092
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Herausgeber
- Oxford University Press (OUP)
- Herausgeber URL
- http://dx.doi.org/10.1093/aje/kwy091
- Datum der Datenerfassung
- 2019
- Titel
- Ramadan Exposure In Utero and Child Mortality in Burkina Faso: Analysis of a Population-Based Cohort Including 41,025 Children
- Ausgabe der Zeitschrift
- 187
Datenquelle: Crossref
- Abstract
- Ramadan exposure in utero can be regarded as a natural experiment with which to study how nutritional conditions in utero influence susceptibility to disease later in life. We analyzed data from rural Burkina Faso on 41,025 children born between 1993 and 2012, of whom 25,093 were born to Muslim mothers. Ramadan exposure was assigned on the basis of overlap between Ramadan dates and gestation, creating 7 exclusive categories. We used proportional hazards regression with difference-in-differences analysis to estimate the association between Ramadan exposure at different gestational ages and mortality among children under 5 years of age. Under-5 mortality was 32 deaths per 1,000 child-years. Under-5 mortality among Muslims was 15% higher than that among non-Muslims (P < 0.001). In the difference-in-differences analysis, the occurrence of Ramadan during conception or the first or second trimester was associated with higher under-5 mortality rates among Muslims only. The mortality rates of children born to Muslim mothers were 33%, 29%, and 22% higher when Ramadan occurred during conception, the first trimester, and the second trimester, respectively, compared with children of non-Muslim mothers born at the same time (P = 0.01, P < 0.001, and P = 0.007). Having a Muslim mother was not associated with mortality when the child was not exposed to Ramadan, born during Ramadan, or exposed during the third trimester. Observance of Ramadan during early pregnancy can have detrimental consequences for the future health of the unborn child.
- Addresses
- Unit of Epidemiology and Biostatistics, Institute of Public Health, Heidelberg University, Heidelberg, Germany.
- Autoren
- Anja Schoeps
- Reyn van Ewijk
- Gisela Kynast-Wolf
- Eric Nebié
- Pascal Zabré
- Ali Sié
- Sabine Gabrysch
- DOI
- 10.1093/aje/kwy091
- eISSN
- 1476-6256
- Externe Identifier
- PubMed Identifier: 29741574
- Funding acknowledgements
- German Research Foundation: 260639091
- Nouna Health and Demographic Surveillance System: SFB 544
- Open access
- false
- ISSN
- 0002-9262
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- American journal of epidemiology
- Schlüsselwörter
- Humans
- Prenatal Exposure Delayed Effects
- Fasting
- Child Mortality
- Proportional Hazards Models
- Regression Analysis
- Cohort Studies
- Demography
- Gestational Age
- Pregnancy
- Islam
- Child, Preschool
- Infant
- Infant, Newborn
- Rural Population
- Burkina Faso
- Female
- Maternal Nutritional Physiological Phenomena
- Sprache
- eng
- Medium
- Paginierung
- 2085 - 2092
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Datum der Datenerfassung
- 2018
- Titel
- Ramadan Exposure In Utero and Child Mortality in Burkina Faso: Analysis of a Population-Based Cohort Including 41,025 Children.
- Sub types
- Research Support, Non-U.S. Gov't
- Journal Article
- Ausgabe der Zeitschrift
- 187
Datenquelle: Europe PubMed Central
- Abstract
- Ramadan exposure in utero can be regarded as a natural experiment with which to study how nutritional conditions in utero influence susceptibility to disease later in life. We analyzed data from rural Burkina Faso on 41,025 children born between 1993 and 2012, of whom 25,093 were born to Muslim mothers. Ramadan exposure was assigned on the basis of overlap between Ramadan dates and gestation, creating 7 exclusive categories. We used proportional hazards regression with difference-in-differences analysis to estimate the association between Ramadan exposure at different gestational ages and mortality among children under 5 years of age. Under-5 mortality was 32 deaths per 1,000 child-years. Under-5 mortality among Muslims was 15% higher than that among non-Muslims (P < 0.001). In the difference-in-differences analysis, the occurrence of Ramadan during conception or the first or second trimester was associated with higher under-5 mortality rates among Muslims only. The mortality rates of children born to Muslim mothers were 33%, 29%, and 22% higher when Ramadan occurred during conception, the first trimester, and the second trimester, respectively, compared with children of non-Muslim mothers born at the same time (P = 0.01, P < 0.001, and P = 0.007). Having a Muslim mother was not associated with mortality when the child was not exposed to Ramadan, born during Ramadan, or exposed during the third trimester. Observance of Ramadan during early pregnancy can have detrimental consequences for the future health of the unborn child.
- Date of acceptance
- 2018
- Autoren
- Anja Schoeps
- Reyn van Ewijk
- Gisela Kynast-Wolf
- Eric Nebié
- Pascal Zabré
- Ali Sié
- Sabine Gabrysch
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/29741574
- DOI
- 10.1093/aje/kwy091
- eISSN
- 1476-6256
- Ausgabe der Veröffentlichung
- 10
- Zeitschrift
- Am J Epidemiol
- Schlüsselwörter
- Burkina Faso
- Child Mortality
- Child, Preschool
- Cohort Studies
- Demography
- Fasting
- Female
- Gestational Age
- Humans
- Infant
- Infant, Newborn
- Islam
- Maternal Nutritional Physiological Phenomena
- Pregnancy
- Prenatal Exposure Delayed Effects
- Proportional Hazards Models
- Regression Analysis
- Rural Population
- Sprache
- eng
- Country
- United States
- Paginierung
- 2085 - 2092
- PII
- 4993217
- Datum der Veröffentlichung
- 2018
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2019
- Titel
- Ramadan Exposure In Utero and Child Mortality in Burkina Faso: Analysis of a Population-Based Cohort Including 41,025 Children.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 187
Datenquelle: PubMed
- Beziehungen:
- Eigentum von