Characterization of new proteins found by analysis of short open reading frames from the full yeast genome
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- MA Andrade
- A Daruvar
- G Casari
- R Schneider
- M Termier
- C Sander
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:A1997YE88500008&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1002/(SICI)1097-0061(199711)13:14<1363::AID-YEA182>3.0.CO;2-8
- Externe Identifier
- Clarivate Analytics Document Solution ID: YE885
- PubMed Identifier: 9392081
- ISSN
- 0749-503X
- Ausgabe der Veröffentlichung
- 14
- Zeitschrift
- YEAST
- Schlüsselwörter
- Saccharomyces cerevisiae
- short ORFs
- computational ORF verification
- ORF properties
- sequence similarity
- Paginierung
- 1363 - 1374
- Datum der Veröffentlichung
- 1997
- Status
- Published
- Titel
- Characterization of new proteins found by analysis of short open reading frames from the full yeast genome
- Sub types
- Article
- Ausgabe der Zeitschrift
- 13
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Autoren
- Miguel A Andrade
- Antoine Daruvar
- Georg Casari
- Reinhard Schneider
- Michel Termier
- Chris Sander
- DOI
- 10.1002/(sici)1097-0061(199711)13:14<1363::aid-yea182>3.0.co;2-8
- eISSN
- 1097-0061
- ISSN
- 0749-503X
- Ausgabe der Veröffentlichung
- 14
- Zeitschrift
- Yeast
- Sprache
- en
- Paginierung
- 1363 - 1374
- Datum der Veröffentlichung
- 1997
- Status
- Published
- Herausgeber
- Wiley
- Herausgeber URL
- http://dx.doi.org/10.1002/(sici)1097-0061(199711)13:14%3C1363::aid-yea182%3E3.0.co;2-8
- Datum der Datenerfassung
- 2021
- Titel
- Characterization of new proteins found by analysis of short open reading frames from the full yeast genome
- Ausgabe der Zeitschrift
- 13
Datenquelle: Crossref
- Abstract
- We have analysed short open reading frames (between 150 and 300 base pairs long) of the yeast genome (Saccharomyces cerevisiae) with a two-step strategy. The first step selects a candidate set of open reading frames from the DNA sequence based on statistical evaluation of DNA and protein sequence properties. The second step filters the candidate set by selecting open reading frames with high similarity to other known sequences (from any organism). As a result, we report ten new predicted proteins not present in the current sequence databases. These include a new alcohol dehydrogenase, a protein probably related to the cell cycle, as well as a homolog of the prokaryotic ribosomal protein L36 likely to be a mitochondrial ribosomal protein coded in the nuclear genome. We conclude that the analysis of short open reading frames leads to biologically interesting discoveries, even though the quantitative yield of new proteins is relatively low.
- Addresses
- European Bioinformatics Institute, European Molecular Biology Laboratory, Cambridge, U.K.
- Autoren
- MA Andrade
- A Daruvar
- G Casari
- R Schneider
- M Termier
- C Sander
- DOI
- 10.1002/(sici)1097-0061(199711)13:14<1363::aid-yea182>3.0.co;2-8
- eISSN
- 1097-0061
- Externe Identifier
- PubMed Identifier: 9392081
- Funding acknowledgements
- Wellcome Trust:
- Open access
- false
- ISSN
- 0749-503X
- Ausgabe der Veröffentlichung
- 14
- Zeitschrift
- Yeast (Chichester, England)
- Schlüsselwörter
- Saccharomyces cerevisiae
- Alcohol Dehydrogenase
- Cell Cycle Proteins
- Fungal Proteins
- Ribosomal Proteins
- Codon
- Evolution, Molecular
- Protein Biosynthesis
- Amino Acid Sequence
- Sequence Homology, Amino Acid
- Frameshift Mutation
- Genome, Fungal
- Open Reading Frames
- Molecular Sequence Data
- Sprache
- eng
- Medium
- Paginierung
- 1363 - 1374
- Datum der Veröffentlichung
- 1997
- Status
- Published
- Datum der Datenerfassung
- 1997
- Titel
- Characterization of new proteins found by analysis of short open reading frames from the full yeast genome.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 13
Datenquelle: Europe PubMed Central
- Abstract
- We have analysed short open reading frames (between 150 and 300 base pairs long) of the yeast genome (Saccharomyces cerevisiae) with a two-step strategy. The first step selects a candidate set of open reading frames from the DNA sequence based on statistical evaluation of DNA and protein sequence properties. The second step filters the candidate set by selecting open reading frames with high similarity to other known sequences (from any organism). As a result, we report ten new predicted proteins not present in the current sequence databases. These include a new alcohol dehydrogenase, a protein probably related to the cell cycle, as well as a homolog of the prokaryotic ribosomal protein L36 likely to be a mitochondrial ribosomal protein coded in the nuclear genome. We conclude that the analysis of short open reading frames leads to biologically interesting discoveries, even though the quantitative yield of new proteins is relatively low.
- Autoren
- MA Andrade
- A Daruvar
- G Casari
- R Schneider
- M Termier
- C Sander
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/9392081
- DOI
- 10.1002/(SICI)1097-0061(199711)13:14<1363::AID-YEA182>3.0.CO;2-8
- Funding acknowledgements
- Wellcome Trust:
- ISSN
- 0749-503X
- Ausgabe der Veröffentlichung
- 14
- Zeitschrift
- Yeast
- Schlüsselwörter
- Alcohol Dehydrogenase
- Amino Acid Sequence
- Cell Cycle Proteins
- Codon
- Evolution, Molecular
- Frameshift Mutation
- Fungal Proteins
- Genome, Fungal
- Molecular Sequence Data
- Open Reading Frames
- Protein Biosynthesis
- Ribosomal Proteins
- Saccharomyces cerevisiae
- Sequence Homology, Amino Acid
- Sprache
- eng
- Country
- England
- Paginierung
- 1363 - 1374
- PII
- 10.1002/(SICI)1097-0061(199711)13:14<1363::AID-YEA182>3.0.CO;2-8
- Datum der Veröffentlichung
- 1997
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 1998
- Titel
- Characterization of new proteins found by analysis of short open reading frames from the full yeast genome.
- Sub types
- Journal Article
- Ausgabe der Zeitschrift
- 13
Datenquelle: PubMed
- Beziehungen:
- Eigentum von