The association of chronic anxiousness with cardiovascular disease and mortality in the community: results from the Gutenberg Health Study
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Abstract
- <jats:title>Abstract</jats:title><jats:p>In a large German community sample of adults, we investigated the association of chronic anxiousness with cardiovascular disease and mortality. Self-reported anxiousness from 11,643 German adults between 40 and 80 years of age from the Gutenberg Health Study (GHS) was analyzed over 5 years. Multivariable regression modeling assessed the relation between the variables, cardiovascular disease and mortality. Twelve percent of the participants reported consistently raised (chronic) anxiousness over at least 2.5 years. Anxiousness was more often reported by female, younger participants with a lower socioeconomic status, smokers and those with a family history of stroke and myocardial infarction. New onset of cardiovascular disease was linked to chronic anxiousness in men and new onset of anxiousness in women. However, chronic anxiousness did not predict all-cause mortality. Our results revealed that anxiousness is highly prevalent in German adults from middle to old age, affecting women in particular. In our study, we found sex-specific associations between new onset of cardiovascular disease and different forms of anxiousness in men and women. We suggest that even subclinical levels of anxiety need to be considered as cardiovascular risk factors. To elucidate potential harm of anxiousness for mental and physical health, we propose sex-specific analyses in further research studies, taking age and the course of anxiousness into account.</jats:p>
- Autoren
- Iris C Reiner
- Ana N Tibubos
- Antonia M Werner
- Mareike Ernst
- Elmar Brähler
- Jörg Wiltink
- Matthias Michal
- Andreas Schulz
- Philipp S Wild
- Thomas Münzel
- Natalie Arnold
- Seyed Hamidreza Mahmoudpour
- Karl J Lackner
- Norbert Pfeiffer
- Manfred E Beutel
- DOI
- 10.1038/s41598-020-69427-8
- eISSN
- 2045-2322
- Ausgabe der Veröffentlichung
- 1
- Zeitschrift
- Scientific Reports
- Sprache
- en
- Artikelnummer
- 12436
- Online publication date
- 2020
- Status
- Published online
- Herausgeber
- Springer Science and Business Media LLC
- Herausgeber URL
- http://dx.doi.org/10.1038/s41598-020-69427-8
- Datum der Datenerfassung
- 2022
- Titel
- The association of chronic anxiousness with cardiovascular disease and mortality in the community: results from the Gutenberg Health Study
- Ausgabe der Zeitschrift
- 10
Datenquelle: Crossref
- Andere Metadatenquellen:
-
- Author's licence
- CC-BY
- Autoren
- Iris Reiner
- Ana N Tibubos
- Antonia M Werner
- Mareike Ernst
- Elmar Brähler
- Jörg Wiltink
- Matthias Michal
- Andreas Schulz
- Philipp S Wild
- Thomas Münzel
- Natalie Arnold
- Seyed Hamidreza Mahmoudpour
- Karl J Lackner
- Norbert Pfeiffer
- Manfred E Beutel
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- JGU-Publikationen
- Resource version
- Published version
- DOI
- 10.1038/s41598-020-69427-8
- Funding acknowledgements
- DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin Mainz
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 2045-2322
- Zeitschrift
- Scientific Reports
- Schlüsselwörter
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 12436
- Datum der Veröffentlichung
- 2020
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/5510
- Herausgeber
- Macmillan Publishers Limited, part of Springer Nature
- Herausgeber URL
- https://doi.org/10.1038/s41598-020-69427-8
- Datum der Datenerfassung
- 2020
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2020
- Zugang
- Public
- Titel
- The association of chronic anxiousness with cardiovascular disease and mortality in the community : results from the Gutenberg Health Study
- Ausgabe der Zeitschrift
- 10
Files
reiner_iris-the_associatio-20201216104304149.pdf
Datenquelle: OPENSCIENCE.UB