Intramuscular Injection of Combined Calf Blood Compound (CFC) and Homeopathic Drug Tr14 Accelerates Muscle Regeneration In Vivo
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Abstract
- <jats:p>Skeletal muscle injuries in competitive sports cause lengthy absences of athletes from tournaments. This is of tremendous competitive and economic relevance for both the athletes and their respective clubs. Therapy for structural muscle lesions aims to promote regeneration and fast-track return-to-play. A common clinical treatment strategy for muscle injuries is the intramuscular injection of calf blood compound and the homeopathic drug, Tr14. Although the combination of these two agents was reported to reduce recovery time, the regulatory mechanism whereby this occurs remains unknown. In this in vivo study, we selected a rat model of mechanical muscle injury to investigate the effect of this combination therapy on muscle regeneration. Gene expression analysis and histological images revealed that this combined intramuscular injection for muscle lesions can enhance the expression of pro-myogenic genes and proteins and accelerate muscle regeneration. These findings are novel and depict the positive effects of calf blood compound and the homeopathic drug, Tr14, which are utilized in the field of Sports medicine.</jats:p>
- Autoren
- Patrick Belikan
- Lisa Nauth
- Lars-Christopher Färber
- Frédéric Abel
- Eva Langendorf
- Philipp Drees
- Pol Maria Rommens
- Ulrike Ritz
- Stefan G Mattyasovszky
- DOI
- 10.3390/ijms21062112
- eISSN
- 1422-0067
- Ausgabe der Veröffentlichung
- 6
- Zeitschrift
- International Journal of Molecular Sciences
- Sprache
- en
- Online publication date
- 2020
- Paginierung
- 2112 - 2112
- Status
- Published online
- Herausgeber
- MDPI AG
- Herausgeber URL
- http://dx.doi.org/10.3390/ijms21062112
- Datum der Datenerfassung
- 2022
- Titel
- Intramuscular Injection of Combined Calf Blood Compound (CFC) and Homeopathic Drug Tr14 Accelerates Muscle Regeneration In Vivo
- Ausgabe der Zeitschrift
- 21
Datenquelle: Crossref
- Andere Metadatenquellen:
-
- Author's licence
- CC-BY
- Autoren
- Patrick Belikan
- Lisa Nauth
- Lars-Christopher Färber
- Frédéric Abel
- Eva Langendorf
- Philipp Drees
- Pol M Rommens
- Ulrike Ritz
- Stefan G Mattyasovszky
- Hosting institution
- Universitätsbibliothek Mainz
- Sammlungen
- JGU-Publikationen
- Resource version
- Published version
- DOI
- 10.3390/ijms21062112
- Funding acknowledgements
- DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin Mainz
- File(s) embargoed
- false
- Open access
- true
- ISSN
- 1422-0067
- Ausgabe der Veröffentlichung
- 6
- Zeitschrift
- International journal of molecular sciences
- Schlüsselwörter
- 570 Biowissenschaften
- 570 Life sciences
- 610 Medizin
- 610 Medical sciences
- Sprache
- eng
- Open access status
- Open Access
- Paginierung
- 2112
- Datum der Veröffentlichung
- 2020
- Public URL
- https://openscience.ub.uni-mainz.de/handle/20.500.12030/5096
- Herausgeber
- MDPI
- Herausgeber URL
- https://doi.org/10.3390/ijms21062112
- Datum der Datenerfassung
- 2020
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2020
- Zugang
- Public
- Titel
- Intramuscular injection of combined calf blood compound (CFC) and homeopathic drug Tr14 accelerates muscle regeneration in vivo
- Ausgabe der Zeitschrift
- 21
Files
belikan_patrick-intramuscular_-20200820174030374.pdf
Datenquelle: OPENSCIENCE.UB