Individualized Web-Based Exercise for the Treatment of Depression: Randomized Controlled Trial

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Nils Haller
  • Sonja Lorenz
  • Daniel Pfirrmann
  • Cora Koch
  • Klaus Lieb
  • Ulrich Dettweiler
  • Perikles Simon
  • Patrick Jung
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000449390400001&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.2196/10698
Externe Identifier
  • Clarivate Analytics Document Solution ID: GZ4SI
  • PubMed Identifier: 30314962
ISSN
2368-7959
Ausgabe der Veröffentlichung
4
Zeitschrift
JMIR MENTAL HEALTH
Schlüsselwörter
  • depression
  • exercise
  • Web-based intervention
  • eHealth
Artikelnummer
ARTN e10698
Datum der Veröffentlichung
2018
Status
Published
Titel
Individualized Web-Based Exercise for the Treatment of Depression: Randomized Controlled Trial
Sub types
  • Article
Ausgabe der Zeitschrift
5

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Abstract
<jats:sec> <jats:title>Background</jats:title> <jats:p>Due to the high prevalence of depressive disorders, it is mandatory to develop therapeutic strategies that provide universal access and require limited financial and human resources. Web-based therapeutic approaches fulfill these conditions.</jats:p> </jats:sec> <jats:sec> <jats:title>Objective</jats:title> <jats:p>The objective of our study was to assess the feasibility, acceptability, and efficacy of a supervised, individualized 8-week Web-based exercise intervention conducted for patients with moderate to severe depression.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>We recruited 20 patients with unipolar depression and randomly assigned them into 2 groups (intervention, exercise program group, n=14, and control, treatment-as-usual group, n=6). At baseline, depressive symptoms were rated via the Quick Inventory of Depressive Symptomatology (QIDS) by patients themselves (QIDS–self-report, QIDS-SR) and by a blinded psychiatrist (QIDS–clinician rating, QIDS-C). In addition, performance diagnostics (lactate analysis, spiroergometry during a treadmill walking test) were conducted. Quality of life was assessed via the Short Form-36 questionnaire (SF-36) and self-efficacy via the General Self-Efficacy scale (GSE). In addition, habitual physical activity (HPA) was determined via the Baecke questionnaire. Participants of the intervention group received exercise schedules once weekly with endurance and strength training instructions. Rating of depressive symptoms was repeated after 6-12 days and 8 weeks; performance diagnostics and the completion of all the questionnaires were repeated after 8 weeks only.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>The severity of depression subsided significantly in the intervention group after 8 weeks (median change in QIDS-SR: −5; interquartile range, IQR: −2 to −10), although it was already evident within the first 6-12 days (median change in QIDS-SR: −6; IQR: −2 to −8). During the intervention, participants undertook a median of 75 (IQR: 63 to 98) minutes of endurance training per week or 84% (16 [IQR: 9 to 19] of 19 [IQR: 15 to 21]) recommended endurance units in total. In addition, 9 (IQR: 4 to 12) of 10 (IQR: 8 to 13) recommended strength training exercise units were conducted during the 8 weeks. Performance diagnostics revealed a substantial increase in the maximum output in Watt for the intervention group after 8 weeks. Moreover, the intervention showed a favorable effect on SF-36 items “emotional well-being” and “social functioning” as well as on GSE and HPA scores.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Our individualized Web-based exercise intervention for moderate to severe depression was highly accepted by the patients and led to a significant and clinically relevant improvement of depressive symptoms.</jats:p> </jats:sec> <jats:sec> <jats:title>Trial Registration</jats:title> <jats:p>ClinicalTrials.gov NCT02874833; https://clinicaltrials.gov/ct2/show/NCT02874833 (Archived by WebCite at http://www.webcitation.org/72ZUUR4tE)</jats:p> </jats:sec>
Autoren
  • Nils Haller
  • Sonja Lorenz
  • Daniel Pfirrmann
  • Cora Koch
  • Klaus Lieb
  • Ulrich Dettweiler
  • Perikles Simon
  • Patrick Jung
DOI
10.2196/10698
eISSN
2368-7959
Ausgabe der Veröffentlichung
4
Zeitschrift
JMIR Mental Health
Sprache
en
Online publication date
2018
Paginierung
e10698 - e10698
Status
Published online
Herausgeber
JMIR Publications Inc.
Herausgeber URL
http://dx.doi.org/10.2196/10698
Datum der Datenerfassung
2019
Titel
Individualized Web-Based Exercise for the Treatment of Depression: Randomized Controlled Trial
Ausgabe der Zeitschrift
5

Datenquelle: Crossref

Abstract
<h4>Background</h4>Due to the high prevalence of depressive disorders, it is mandatory to develop therapeutic strategies that provide universal access and require limited financial and human resources. Web-based therapeutic approaches fulfill these conditions.<h4>Objective</h4>The objective of our study was to assess the feasibility, acceptability, and efficacy of a supervised, individualized 8-week Web-based exercise intervention conducted for patients with moderate to severe depression.<h4>Methods</h4>We recruited 20 patients with unipolar depression and randomly assigned them into 2 groups (intervention, exercise program group, n=14, and control, treatment-as-usual group, n=6). At baseline, depressive symptoms were rated via the Quick Inventory of Depressive Symptomatology (QIDS) by patients themselves (QIDS-self-report, QIDS-SR) and by a blinded psychiatrist (QIDS-clinician rating, QIDS-C). In addition, performance diagnostics (lactate analysis, spiroergometry during a treadmill walking test) were conducted. Quality of life was assessed via the Short Form-36 questionnaire (SF-36) and self-efficacy via the General Self-Efficacy scale (GSE). In addition, habitual physical activity (HPA) was determined via the Baecke questionnaire. Participants of the intervention group received exercise schedules once weekly with endurance and strength training instructions. Rating of depressive symptoms was repeated after 6-12 days and 8 weeks; performance diagnostics and the completion of all the questionnaires were repeated after 8 weeks only.<h4>Results</h4>The severity of depression subsided significantly in the intervention group after 8 weeks (median change in QIDS-SR: -5; interquartile range, IQR: -2 to -10), although it was already evident within the first 6-12 days (median change in QIDS-SR: -6; IQR: -2 to -8). During the intervention, participants undertook a median of 75 (IQR: 63 to 98) minutes of endurance training per week or 84% (16 [IQR: 9 to 19] of 19 [IQR: 15 to 21]) recommended endurance units in total. In addition, 9 (IQR: 4 to 12) of 10 (IQR: 8 to 13) recommended strength training exercise units were conducted during the 8 weeks. Performance diagnostics revealed a substantial increase in the maximum output in Watt for the intervention group after 8 weeks. Moreover, the intervention showed a favorable effect on SF-36 items "emotional well-being" and "social functioning" as well as on GSE and HPA scores.<h4>Conclusions</h4>Our individualized Web-based exercise intervention for moderate to severe depression was highly accepted by the patients and led to a significant and clinically relevant improvement of depressive symptoms.<h4>Trial registration</h4>ClinicalTrials.gov NCT02874833; https://clinicaltrials.gov/ct2/show/NCT02874833 (Archived by WebCite at http://www.webcitation.org/72ZUUR4tE).
Addresses
  • Department of Sports Medicine, Rehabilitation and Disease Prevention, Johannes Gutenberg-University, Mainz, Germany.
Autoren
  • Nils Haller
  • Sonja Lorenz
  • Daniel Pfirrmann
  • Cora Koch
  • Klaus Lieb
  • Ulrich Dettweiler
  • Perikles Simon
  • Patrick Jung
DOI
10.2196/10698
eISSN
2368-7959
Externe Identifier
  • PubMed Identifier: 30314962
  • PubMed Central ID: PMC6234340
Open access
true
ISSN
2368-7959
Ausgabe der Veröffentlichung
4
Zeitschrift
JMIR mental health
Sprache
eng
Medium
Electronic
Online publication date
2018
Open access status
Open Access
Paginierung
e10698
Datum der Veröffentlichung
2018
Status
Published
Publisher licence
CC BY
Datum der Datenerfassung
2018
Titel
Individualized Web-Based Exercise for the Treatment of Depression: Randomized Controlled Trial.
Sub types
  • research-article
  • Journal Article
Ausgabe der Zeitschrift
5

Datenquelle: Europe PubMed Central

Abstract
BACKGROUND: Due to the high prevalence of depressive disorders, it is mandatory to develop therapeutic strategies that provide universal access and require limited financial and human resources. Web-based therapeutic approaches fulfill these conditions. OBJECTIVE: The objective of our study was to assess the feasibility, acceptability, and efficacy of a supervised, individualized 8-week Web-based exercise intervention conducted for patients with moderate to severe depression. METHODS: We recruited 20 patients with unipolar depression and randomly assigned them into 2 groups (intervention, exercise program group, n=14, and control, treatment-as-usual group, n=6). At baseline, depressive symptoms were rated via the Quick Inventory of Depressive Symptomatology (QIDS) by patients themselves (QIDS-self-report, QIDS-SR) and by a blinded psychiatrist (QIDS-clinician rating, QIDS-C). In addition, performance diagnostics (lactate analysis, spiroergometry during a treadmill walking test) were conducted. Quality of life was assessed via the Short Form-36 questionnaire (SF-36) and self-efficacy via the General Self-Efficacy scale (GSE). In addition, habitual physical activity (HPA) was determined via the Baecke questionnaire. Participants of the intervention group received exercise schedules once weekly with endurance and strength training instructions. Rating of depressive symptoms was repeated after 6-12 days and 8 weeks; performance diagnostics and the completion of all the questionnaires were repeated after 8 weeks only. RESULTS: The severity of depression subsided significantly in the intervention group after 8 weeks (median change in QIDS-SR: -5; interquartile range, IQR: -2 to -10), although it was already evident within the first 6-12 days (median change in QIDS-SR: -6; IQR: -2 to -8). During the intervention, participants undertook a median of 75 (IQR: 63 to 98) minutes of endurance training per week or 84% (16 [IQR: 9 to 19] of 19 [IQR: 15 to 21]) recommended endurance units in total. In addition, 9 (IQR: 4 to 12) of 10 (IQR: 8 to 13) recommended strength training exercise units were conducted during the 8 weeks. Performance diagnostics revealed a substantial increase in the maximum output in Watt for the intervention group after 8 weeks. Moreover, the intervention showed a favorable effect on SF-36 items "emotional well-being" and "social functioning" as well as on GSE and HPA scores. CONCLUSIONS: Our individualized Web-based exercise intervention for moderate to severe depression was highly accepted by the patients and led to a significant and clinically relevant improvement of depressive symptoms. TRIAL REGISTRATION: ClinicalTrials.gov NCT02874833; https://clinicaltrials.gov/ct2/show/NCT02874833 (Archived by WebCite at http://www.webcitation.org/72ZUUR4tE).
Date of acceptance
2018
Autoren
  • Nils Haller
  • Sonja Lorenz
  • Daniel Pfirrmann
  • Cora Koch
  • Klaus Lieb
  • Ulrich Dettweiler
  • Perikles Simon
  • Patrick Jung
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/30314962
DOI
10.2196/10698
Externe Identifier
  • PubMed Central ID: PMC6234340
ISSN
2368-7959
Ausgabe der Veröffentlichung
4
Zeitschrift
JMIR Ment Health
Schlüsselwörter
  • Web-based intervention
  • depression
  • eHealth
  • exercise
Sprache
eng
Country
Canada
Paginierung
e10698
PII
v5i4e10698
Datum der Veröffentlichung
2018
Status
Published online
Titel
Individualized Web-Based Exercise for the Treatment of Depression: Randomized Controlled Trial.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
5

Datenquelle: PubMed

Author's licence
CC-BY
Autoren
  • Nils Haller
  • Sonja Lorenz
  • Daniel Pfirrmann
  • Cora Koch
  • Klaus Lieb
  • Ulrich Dettweiler
  • Perikles Simon
  • Patrick Jung
Hosting institution
Universitätsbibliothek Mainz
Sammlungen
  • JGU-Publikationen
Resource version
Published version
URN
urn:nbn:de:hebis:77-publ-586603
DOI
10.2196/10698
Funding acknowledgements
  • DFG, Open Access-Publizieren Universität Mainz / Universitätsmedizin
File(s) embargoed
false
Open access
true
ISSN
2368-7959
Ausgabe der Veröffentlichung
4
Zeitschrift
Journal of medical internet research : Mental Health
Schlüsselwörter
  • 610 Medizin
  • 610 Medical sciences
Sprache
eng
Open access status
Open Access
Paginierung
e10698
Datum der Veröffentlichung
2018
Public URL
https://openscience.ub.uni-mainz.de/handle/20.500.12030/763
Herausgeber
JMIR Publications Inc.
Herausgeber URL
http://dx.doi.org/10.2196/10698
Datum der Datenerfassung
2018
Datum, an dem der Datensatz öffentlich gemacht wurde
2018
Zugang
Public
Titel
Individualized web-based exercise for the treatment of depression : randomized controlled trial
Ausgabe der Zeitschrift
5

Files

58660.pdf

Datenquelle: OPENSCIENCE.UB

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