Relayed hyperpolarization for zero-field nuclear magnetic resonance

Publikationstyp:
Zeitschriftenaufsatz
Metadaten:
Autoren
  • Erik T Van Dyke
  • James Eills
  • Roman Picazo-Frutos
  • Kirill F Sheberstov
  • Yinan Hu
  • Dmitry Budker
  • Danila A Barskiy
Autoren-URL
https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000828233900023&DestLinkType=FullRecord&DestApp=WOS_CPL
DOI
10.1126/sciadv.abp9242
Externe Identifier
  • Clarivate Analytics Document Solution ID: 3B9CW
  • PubMed Identifier: 35857837
ISSN
2375-2548
Ausgabe der Veröffentlichung
29
Zeitschrift
SCIENCE ADVANCES
Artikelnummer
ARTN eabp9242
Datum der Veröffentlichung
2022
Status
Published
Titel
Relayed hyperpolarization for zero-field nuclear magnetic resonance
Sub types
  • Article
Ausgabe der Zeitschrift
8

Datenquelle: Web of Science (Lite)

Andere Metadatenquellen:
Abstract
<jats:p> Zero- to ultralow-field nuclear magnetic resonance (ZULF NMR) is a rapidly developing form of spectroscopy that provides rich spectroscopic information in the absence of large magnetic fields. However, signal acquisition still requires a mechanism for generating a bulk magnetic moment for detection, and the currently used methods only apply to a limited pool of chemicals or come at prohibitively high cost. We demonstrate that the parahydrogen-based SABRE (signal amplification by reversible exchange)–Relay method can be used as a more general means of generating hyperpolarized analytes for ZULF NMR by observing zero-field <jats:italic>J</jats:italic> -spectra of [ <jats:sup>13</jats:sup> C]-methanol, [1- <jats:sup>13</jats:sup> C]-ethanol, and [2- <jats:sup>13</jats:sup> C]-ethanol in both <jats:sup>13</jats:sup> C-isotopically enriched and natural abundance samples. We explore the magnetic field dependence of the SABRE-Relay efficiency and show the existence of a second maximum at 19.0 ± 0.3 mT. Despite presence of water, SABRE-Relay is used to hyperpolarize ethanol extracted from a store-bought sample of vodka (% <jats:italic>P</jats:italic> <jats:sub>H</jats:sub> ~ 0.1%). </jats:p>
Autoren
  • Erik T Van Dyke
  • James Eills
  • Román Picazo-Frutos
  • Kirill F Sheberstov
  • Yinan Hu
  • Dmitry Budker
  • Danila A Barskiy
DOI
10.1126/sciadv.abp9242
eISSN
2375-2548
Ausgabe der Veröffentlichung
29
Zeitschrift
Science Advances
Sprache
en
Datum der Veröffentlichung
2022
Status
Published
Herausgeber
American Association for the Advancement of Science (AAAS)
Herausgeber URL
http://dx.doi.org/10.1126/sciadv.abp9242
Datum der Datenerfassung
2024
Titel
Relayed hyperpolarization for zero-field nuclear magnetic resonance
Ausgabe der Zeitschrift
8

Datenquelle: Crossref

Abstract
Zero- to ultralow-field nuclear magnetic resonance (ZULF NMR) is a rapidly developing form of spectroscopy that provides rich spectroscopic information in the absence of large magnetic fields. However, signal acquisition still requires a mechanism for generating a bulk magnetic moment for detection, and the currently used methods only apply to a limited pool of chemicals or come at prohibitively high cost. We demonstrate that the parahydrogen-based SABRE (signal amplification by reversible exchange)-Relay method can be used as a more general means of generating hyperpolarized analytes for ZULF NMR by observing zero-field <i>J</i>-spectra of [<sup>13</sup>C]-methanol, [1-<sup>13</sup>C]-ethanol, and [2-<sup>13</sup>C]-ethanol in both <sup>13</sup>C-isotopically enriched and natural abundance samples. We explore the magnetic field dependence of the SABRE-Relay efficiency and show the existence of a second maximum at 19.0 ± 0.3 mT. Despite presence of water, SABRE-Relay is used to hyperpolarize ethanol extracted from a store-bought sample of vodka (%<i>P</i><sub>H</sub> ~ 0.1%).
Addresses
  • Institut für Physik, Johannes Gutenberg Universität Mainz, 55128 Mainz, Germany.
Autoren
  • Erik T Van Dyke
  • James Eills
  • Román Picazo-Frutos
  • Kirill F Sheberstov
  • Yinan Hu
  • Dmitry Budker
  • Danila A Barskiy
DOI
10.1126/sciadv.abp9242
eISSN
2375-2548
Externe Identifier
  • PubMed Identifier: 35857837
  • PubMed Central ID: PMC9299534
Open access
true
ISSN
2375-2548
Ausgabe der Veröffentlichung
29
Zeitschrift
Science advances
Sprache
eng
Medium
Print-Electronic
Online publication date
2022
Open access status
Open Access
Paginierung
eabp9242
Datum der Veröffentlichung
2022
Status
Published
Publisher licence
CC BY-NC
Datum der Datenerfassung
2022
Titel
Relayed hyperpolarization for zero-field nuclear magnetic resonance.
Sub types
  • research-article
  • Journal Article
Ausgabe der Zeitschrift
8

Files

https://www.science.org/doi/pdf/10.1126/sciadv.abp9242?download=true https://europepmc.org/articles/PMC9299534?pdf=render

Datenquelle: Europe PubMed Central

Abstract
Zero- to ultralow-field nuclear magnetic resonance (ZULF NMR) is a rapidly developing form of spectroscopy that provides rich spectroscopic information in the absence of large magnetic fields. However, signal acquisition still requires a mechanism for generating a bulk magnetic moment for detection, and the currently used methods only apply to a limited pool of chemicals or come at prohibitively high cost. We demonstrate that the parahydrogen-based SABRE (signal amplification by reversible exchange)-Relay method can be used as a more general means of generating hyperpolarized analytes for ZULF NMR by observing zero-field J-spectra of [13C]-methanol, [1-13C]-ethanol, and [2-13C]-ethanol in both 13C-isotopically enriched and natural abundance samples. We explore the magnetic field dependence of the SABRE-Relay efficiency and show the existence of a second maximum at 19.0 ± 0.3 mT. Despite presence of water, SABRE-Relay is used to hyperpolarize ethanol extracted from a store-bought sample of vodka (%PH ~ 0.1%).
Autoren
  • Erik T Van Dyke
  • James Eills
  • Román Picazo-Frutos
  • Kirill F Sheberstov
  • Yinan Hu
  • Dmitry Budker
  • Danila A Barskiy
Autoren-URL
https://www.ncbi.nlm.nih.gov/pubmed/35857837
DOI
10.1126/sciadv.abp9242
eISSN
2375-2548
Externe Identifier
  • PubMed Central ID: PMC9299534
Ausgabe der Veröffentlichung
29
Zeitschrift
Sci Adv
Sprache
eng
Country
United States
Paginierung
eabp9242
Datum der Veröffentlichung
2022
Status
Published
Titel
Relayed hyperpolarization for zero-field nuclear magnetic resonance.
Sub types
  • Journal Article
Ausgabe der Zeitschrift
8

Datenquelle: PubMed

Author's licence
CC-BY-NC
Autoren
  • Erik T Van Dyke
  • James Eills
  • Román Picazo-Frutos
  • Kirill F Sheberstov
  • Yinan Hu
  • Dmitry Budker
  • Danila A Barskiy
Hosting institution
Universitätsbibliothek Mainz
Sammlungen
  • DFG-491381577-G
Resource version
Published version
DOI
10.1126/sciadv.abp9242
File(s) embargoed
false
Open access
true
ISSN
2375-2548
Ausgabe der Veröffentlichung
29
Zeitschrift
Science advances
Schlüsselwörter
  • 530 Physik
  • 530 Physics
Sprache
eng
Open access status
Open Access
Paginierung
eabp9242
Datum der Veröffentlichung
2022
Public URL
https://openscience.ub.uni-mainz.de/handle/20.500.12030/10076
Herausgeber
American Association for the Advancement of Science
Datum der Datenerfassung
2024
Datum, an dem der Datensatz öffentlich gemacht wurde
2024
Zugang
Public
Titel
Relayed hyperpolarization for zero-field nuclear magnetic resonance
Ausgabe der Zeitschrift
8

Files

relayed_hyperpolarization_for-20231017205646224.pdf

Datenquelle: OPENSCIENCE.UB

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