pH-Switchable Self-Assembled Materials
- Publikationstyp:
- Zeitschriftenaufsatz
- Metadaten:
-
- Autoren
- Hendrik Frisch
- Pol Besenius
- Autoren-URL
- https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=fis-test-1&SrcAuth=WosAPI&KeyUT=WOS:000349989400001&DestLinkType=FullRecord&DestApp=WOS_CPL
- DOI
- 10.1002/marc.201400623
- eISSN
- 1521-3927
- Externe Identifier
- Clarivate Analytics Document Solution ID: CB9YC
- PubMed Identifier: 25534871
- ISSN
- 1022-1336
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- MACROMOLECULAR RAPID COMMUNICATIONS
- Schlüsselwörter
- supramolecular materials
- stimuli-responsive
- pH-regulation
- self-assembly in water
- molecular recognition
- Paginierung
- 346 - 363
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Titel
- pH-Switchable Self-Assembled Materials
- Sub types
- Article
- Ausgabe der Zeitschrift
- 36
Datenquelle: Web of Science (Lite)
- Andere Metadatenquellen:
-
- Abstract
- <jats:p>Self‐assembled materials, which are able to respond to external stimuli, have been extensively studied over the last decades. A particularly exciting stimulus for a wide range of biomedical applications is the pH value of aqueous solutions, since deprotonation‐protonation events are crucial for structural and functional properties of biopolymers. In living cells and tissues, intra‐ and extracellular pH values are stringently regulated, but can deviate from pH neutral as observed for example in tumorous, inflammatory sites, in endocytic pathways, and specific cellular compartments. By using a pH‐switch as a stimulus, it is thereby possible to address specific targets in order to cause a programmed response of the supramolecular material. This strategy has not only been successfully applied in fundamental research but also in clinical studies. In this feature article, current strategies that have been used in order to design materials with pH‐responsive properties are illustrated. This discussion only addresses selected examples from the last four years, the self‐assembly of polymer‐based building blocks, assemblies emerging from small molecules including surfactants or derived from biological macromolecules, and finally the controlled self‐assembly of oligopeptides. <jats:boxed-text content-type="graphic" position="anchor"><jats:graphic xmlns:xlink="http://www.w3.org/1999/xlink" mimetype="image/png" position="anchor" specific-use="enlarged-web-image" xlink:href="graphic/marc201400623-abs-0001-m.png"><jats:alt-text>image</jats:alt-text></jats:graphic></jats:boxed-text></jats:p>
- Autoren
- Hendrik Frisch
- Pol Besenius
- DOI
- 10.1002/marc.201400623
- eISSN
- 1521-3927
- ISSN
- 1022-1336
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Macromolecular Rapid Communications
- Sprache
- en
- Online publication date
- 2014
- Paginierung
- 346 - 363
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Herausgeber
- Wiley
- Herausgeber URL
- http://dx.doi.org/10.1002/marc.201400623
- Datum der Datenerfassung
- 2023
- Titel
- pH‐Switchable Self‐Assembled Materials
- Ausgabe der Zeitschrift
- 36
Datenquelle: Crossref
- Abstract
- Self-assembled materials, which are able to respond to external stimuli, have been extensively studied over the last decades. A particularly exciting stimulus for a wide range of biomedical applications is the pH value of aqueous solutions, since deprotonation-protonation events are crucial for structural and functional properties of biopolymers. In living cells and tissues, intra- and extracellular pH values are stringently regulated, but can deviate from pH neutral as observed for example in tumorous, inflammatory sites, in endocytic pathways, and specific cellular compartments. By using a pH-switch as a stimulus, it is thereby possible to address specific targets in order to cause a programmed response of the supramolecular material. This strategy has not only been successfully applied in fundamental research but also in clinical studies. In this feature article, current strategies that have been used in order to design materials with pH-responsive properties are illustrated. This discussion only addresses selected examples from the last four years, the self-assembly of polymer-based building blocks, assemblies emerging from small molecules including surfactants or derived from biological macromolecules, and finally the controlled self-assembly of oligopeptides.
- Addresses
- Organic Chemistry Institute and CeNTech, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, D-48149, Münster, Germany.
- Autoren
- Hendrik Frisch
- Pol Besenius
- DOI
- 10.1002/marc.201400623
- eISSN
- 1521-3927
- Externe Identifier
- PubMed Identifier: 25534871
- Open access
- false
- ISSN
- 1022-1336
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Macromolecular rapid communications
- Schlüsselwörter
- Crown Ethers
- Macromolecular Substances
- Polymers
- Tannins
- Oligopeptides
- Capsid Proteins
- Hydrogels
- Fluorescent Dyes
- Hydrogen-Ion Concentration
- Nanotubes
- Sprache
- eng
- Medium
- Print-Electronic
- Online publication date
- 2014
- Paginierung
- 346 - 363
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Datum der Datenerfassung
- 2014
- Titel
- pH-switchable self-assembled materials.
- Sub types
- Research Support, Non-U.S. Gov't
- Journal Article
- Ausgabe der Zeitschrift
- 36
Datenquelle: Europe PubMed Central
- Abstract
- Self-assembled materials, which are able to respond to external stimuli, have been extensively studied over the last decades. A particularly exciting stimulus for a wide range of biomedical applications is the pH value of aqueous solutions, since deprotonation-protonation events are crucial for structural and functional properties of biopolymers. In living cells and tissues, intra- and extracellular pH values are stringently regulated, but can deviate from pH neutral as observed for example in tumorous, inflammatory sites, in endocytic pathways, and specific cellular compartments. By using a pH-switch as a stimulus, it is thereby possible to address specific targets in order to cause a programmed response of the supramolecular material. This strategy has not only been successfully applied in fundamental research but also in clinical studies. In this feature article, current strategies that have been used in order to design materials with pH-responsive properties are illustrated. This discussion only addresses selected examples from the last four years, the self-assembly of polymer-based building blocks, assemblies emerging from small molecules including surfactants or derived from biological macromolecules, and finally the controlled self-assembly of oligopeptides.
- Autoren
- Hendrik Frisch
- Pol Besenius
- Autoren-URL
- https://www.ncbi.nlm.nih.gov/pubmed/25534871
- DOI
- 10.1002/marc.201400623
- eISSN
- 1521-3927
- Ausgabe der Veröffentlichung
- 4
- Zeitschrift
- Macromol Rapid Commun
- Schlüsselwörter
- molecular recognition
- pH-regulation
- self-assembly in water
- stimuli-responsive
- supramolecular materials
- Capsid Proteins
- Crown Ethers
- Fluorescent Dyes
- Hydrogels
- Hydrogen-Ion Concentration
- Macromolecular Substances
- Nanotubes
- Oligopeptides
- Polymers
- Tannins
- Sprache
- eng
- Country
- Germany
- Paginierung
- 346 - 363
- Datum der Veröffentlichung
- 2015
- Status
- Published
- Datum, an dem der Datensatz öffentlich gemacht wurde
- 2015
- Titel
- pH-switchable self-assembled materials.
- Sub types
- Journal Article
- Research Support, Non-U.S. Gov't
- Ausgabe der Zeitschrift
- 36
Datenquelle: PubMed
- Beziehungen:
-